Strongyloides stercoralis Infection at Different Altitudes of the Cusco Region in Peru

Baca-Turpo, Benicia; Fernandez-Baca, Martha Vanessa; Farfan-Gonzales, Nedhy; Mamani-Licona, Frecia Maribel; Anjum, Seher; Chaman-Illanes, Yeshica; Lopez, Martha; Ly, Priscilla; Morales Fernández, María Luisa; Valdivia-Rodriguez, Angela Maria; Cabada, Miguel Mauricio

dc.contributor.author	Morales Fernández, María Luisa
dc.contributor.author	Lopez, Martha
dc.contributor.author	Ly, Priscilla
dc.contributor.author	Anjum, Seher
dc.contributor.author	Fernandez-Baca, Martha Vanessa
dc.contributor.author	Valdivia-Rodriguez, Angela Maria
dc.contributor.author	Mamani-Licona, Frecia Maribel
dc.contributor.author	Baca-Turpo, Benicia
dc.contributor.author	Farfan-Gonzales, Nedhy
dc.contributor.author	Chaman-Illanes, Yeshica
dc.contributor.author	Cabada, Miguel Mauricio
dc.date.accessioned	2019-08-08T15:23:44Z
dc.date.available	2019-08-08T15:23:44Z
dc.date.issued	2019
dc.identifier.uri	https://hdl.handle.net/20.500.12866/7121
dc.description.abstract	Strongyloides stercoralis affects 30-100 million people worldwide. The burden is underestimated because of the paucity of studies, limited geographical areas surveyed, and poor quality of diagnostic tests. This study aimed at determining the epidemiology of strongyloidiasis using sensitive microscopy testing in rural populations living at different altitudes in Cusco, Peru. Data were collected from subjects aged > 3 years living in Quellouno (elevation 2,600 ft) and Limatambo (elevation 8,379 ft) districts. Subjects provided one fresh stool sample and answer a standardized questionnaire. Fresh stool was tested on site using the Baermann's test and agar plate culture. Formalin-preserved stool was tested by rapid sedimentation. Eighty percent (585/715) of eligible subjects consented to participate; after excluding subjects with missing data, 65% (462/715) were included. Fifty-five percentage were female; the median age was 33 years (interquartile range 13-52), and 72% had government health insurance. Half had intestinal parasites, and Strongyloides was the most common (24.5%) followed by Giardia (15.5%), Blastocystis (14.9%), and hookworm (11.5%). The agar plate culture detected more cases of Strongyloides than Baermann's or sedimentation tests. Strongyloides infection was more common at low altitude (26.4%) than at high altitude (18.6%), but the difference was not statistically significant (P = 0.08). Older age, walking barefoot, bathing in rivers/streams, and using municipal sewage were associated with strongyloidiasis. Strongyloides was the most prevalent parasite in the areas studied and was associated with demographic, socioeconomic, and sanitary factors.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	adolescent	en_US
dc.subject	adult	en_US
dc.subject	altitude	en_US
dc.subject	Article	en_US
dc.subject	Blastocystis	en_US
dc.subject	disease association	en_US
dc.subject	feces analysis	en_US
dc.subject	female	en_US
dc.subject	formaldehyde	en_US
dc.subject	Giardia	en_US
dc.subject	health insurance	en_US
dc.subject	hookworm	en_US
dc.subject	human	en_US
dc.subject	major clinical study	en_US
dc.subject	male	en_US
dc.subject	nonhuman	en_US
dc.subject	parasite examination	en_US
dc.subject	Peru	en_US
dc.subject	rural population	en_US
dc.subject	sedimentation	en_US
dc.subject	sewage	en_US
dc.subject	stream (river)	en_US
dc.subject	Strongyloides	en_US
dc.subject	strongyloidiasis	en_US
dc.subject	walking	en_US
dc.title	Strongyloides stercoralis Infection at Different Altitudes of the Cusco Region in Peru	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.18-0568
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645