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dc.contributor.author Zaldivar Villon, M.L.F.
dc.contributor.author de la Rocha, J.A.L.
dc.contributor.author Espinoza, L.R.
dc.date.accessioned 2019-08-08T15:23:45Z
dc.date.available 2019-08-08T15:23:45Z
dc.date.issued 2019
dc.identifier.uri https://hdl.handle.net/20.500.12866/7136
dc.description.abstract Purpose of Review: Takayasu arteritis (TA) is a granulomatous inflammatory disorder that affects large vessels, especially aorta and its proximal branches. Its diagnosis can be extremely challenging due to the non-specificity of the systemic inflammatory manifestations during the early phase of the disease and usually follows an insidious clinical course until the emergence of vascular ischemic complications. Recent Findings: Its pathogenesis has been better delineated in recent years, especially the role of HLA-B*52 allele in certain ethnic groups, as well as the use of biological therapy, and surgical revascularization. Recent findings are discussed in depth. Summary: Clinical and epidemiological aspects of TA, recent developments in pathogenesis, and therapy are presented. en_US
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartofseries Current Rheumatology Reports
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject epidemiology en_US
dc.subject human en_US
dc.subject ethnicity en_US
dc.subject Review en_US
dc.subject heart muscle revascularization en_US
dc.subject Aortitis en_US
dc.subject fluorodeoxyglucose f 18 en_US
dc.subject positron emission tomography en_US
dc.subject allele en_US
dc.subject tumor necrosis factor en_US
dc.subject biological therapy en_US
dc.subject clinical feature en_US
dc.subject nuclear magnetic resonance imaging en_US
dc.subject pathogenesis en_US
dc.subject disease activity en_US
dc.subject glucocorticoid en_US
dc.subject computer assisted tomography en_US
dc.subject disease classification en_US
dc.subject cyclophosphamide en_US
dc.subject methotrexate en_US
dc.subject echography en_US
dc.subject interleukin 17 en_US
dc.subject interleukin 6 en_US
dc.subject interleukin 8 en_US
dc.subject laboratory test en_US
dc.subject interleukin 9 en_US
dc.subject abatacept en_US
dc.subject azathioprine en_US
dc.subject leflunomide en_US
dc.subject rituximab en_US
dc.subject mycophenolate mofetil en_US
dc.subject angiography en_US
dc.subject aortic arch syndrome en_US
dc.subject artery lesion en_US
dc.subject Biologic therapy en_US
dc.subject cardiac imaging en_US
dc.subject CD19 antigen en_US
dc.subject CD20 antigen en_US
dc.subject CD27 antigen en_US
dc.subject Granulomatous disease en_US
dc.subject HLA B52 antigen en_US
dc.subject Imaging studies en_US
dc.subject interleukin 18 en_US
dc.subject magnetic resonance angiography en_US
dc.subject Surgical revascularization en_US
dc.subject tocilizumab en_US
dc.subject Vasculitis en_US
dc.title Takayasu Arteritis: Recent Developments en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1007/s11926-019-0848-3
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.17
dc.relation.issn 1534-6307


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