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Detection of human Metapneumovirus infection in children under 18 years old hospitalized in Lima-Peru.

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dc.contributor.author Del Valle-Mendoza, Juana
dc.contributor.author Orellana-Peralta, Fiorella
dc.contributor.author Del Valle, Luis J.
dc.contributor.author Verne, Eduardo
dc.contributor.author Ugarte, Claudia
dc.contributor.author Weilg, Claudia
dc.contributor.author Silva-Caso, Wilmer
dc.contributor.author Valverde-Ezeta, Jorge
dc.contributor.author Carrillo-Ng, Hugo
dc.contributor.author Pena-Tuesta, Isaac
dc.contributor.author Palomares-Reyes, Carlos
dc.contributor.author Cornejo-Tapia, Angela
dc.contributor.author Aguilar-Luis, Miguel Angel
dc.date.accessioned 2019-12-06T20:57:46Z
dc.date.available 2019-12-06T20:57:46Z
dc.date.issued 2019
dc.identifier.uri https://hdl.handle.net/20.500.12866/7400
dc.description.abstract Background: Human Metapneumovirus (hMPV) is a negative single-stranded RNA virus. Infection by hMPV mainly affects the pediatric population and can cause upper or lower respiratory tract pathologies which can develop life threating complications. This study was carried out between 2009 and 2010 in a high complexity national hospital in Lima, Peru. The time frame corresponds to the pandemic of influenza A H1N1. Methods: A prospective study was performed between September 2009 and September 2010. Patients with a clinical diagnosis suggestive of an acute respiratory infection were included. RT-PCR was utilized to attain the amplification and identification of the hMPV. Results: A total of 539 samples were analyzed from patients with a clinical context suggestive of an acute respiratory tract infection. Of these samples 73, (13.54%) were positive for hMPV. Out of the positive cases, 63% were under one year old, and increased to nearly 80% when considering children younger than two years old. Cough was the most frequent symptom presented by our population with a number of 62 cases (84.93%). Viral seasonality was also established, noting its predominance during the months of summer in the southern hemisphere. The infection by hMPV has an important prevalence in Peru. It mainly affects children under one year old and should be considered an important differential diagnosis in a patient with an acute respiratory infection. en_US
dc.language.iso eng
dc.publisher PeerJ
dc.relation.ispartof urn:issn:2167-8359
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject acute disease en_US
dc.subject Acute obstructive bronchitis en_US
dc.subject Acute respiratory tract infection en_US
dc.subject adolescent en_US
dc.subject Article en_US
dc.subject child en_US
dc.subject coughing en_US
dc.subject differential diagnosis en_US
dc.subject hospitalized child en_US
dc.subject human en_US
dc.subject Human metapneumovirus en_US
dc.subject Human metapneumovirus infection en_US
dc.subject major clinical study en_US
dc.subject nonhuman en_US
dc.subject Pediatrics en_US
dc.subject Peru en_US
dc.subject Polymerase chain reaction en_US
dc.subject prevalence en_US
dc.subject prospective study en_US
dc.subject respiratory tract infection en_US
dc.subject reverse transcription polymerase chain reaction en_US
dc.subject seasonal variation en_US
dc.subject summer en_US
dc.subject symptom en_US
dc.subject viral respiratory tract infection en_US
dc.subject virus detection en_US
dc.subject virus RNA en_US
dc.title Detection of human Metapneumovirus infection in children under 18 years old hospitalized in Lima-Peru. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.7717/peerj.7266
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE


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