Soil-transmitted helminthiasis in children from a rural community taking part in a periodic deworming program in the Peruvian Amazon

Duque, Kevin R.; Gallegos, Rodrigo; Vasquez-Rios, George; Baca, Katia P.; Samalvides Cuba, Frine; Errea, Renato A.; Canales, Marco; Marcos, Luis A.; Uriol, Celene; Terashima, Angelica; Fabian, Rosario J.; Calderon, Maria L.; Siu, Diego; Juarez, Luciana H.; Rondon, Claudia R.

dc.contributor.author	Errea, Renato A.
dc.contributor.author	Vasquez-Rios, George
dc.contributor.author	Calderon, Maria L.
dc.contributor.author	Siu, Diego
dc.contributor.author	Duque, Kevin R.
dc.contributor.author	Juarez, Luciana H.
dc.contributor.author	Gallegos, Rodrigo
dc.contributor.author	Uriol, Celene
dc.contributor.author	Rondon, Claudia R.
dc.contributor.author	Baca, Katia P.
dc.contributor.author	Fabian, Rosario J.
dc.contributor.author	Canales, Marco
dc.contributor.author	Terashima, Angelica
dc.contributor.author	Marcos, Luis A.
dc.contributor.author	Samalvides Cuba, Frine
dc.date.accessioned	2019-12-06T20:57:48Z
dc.date.available	2019-12-06T20:57:48Z
dc.date.issued	2019
dc.identifier.uri	https://hdl.handle.net/20.500.12866/7427
dc.description.abstract	Children in the Peruvian Amazon Basin are at risk of soil-transmitted helminths (STH) infections. This study aimed to determine the prevalence of STH infection in children from a rural Amazonian community of Peru and to elucidate epidemiological risk factors associated with its perpetuation while on a school-based deworming program with mebendazole. Stool samples of children aged 2–14 years and their mothers were analyzed through direct smear analysis, Kato–Katz, spontaneous sedimentation in tube, Baermann’s method, and agar plate culture. A questionnaire was administered to collect epidemiological information of interest. Among 124 children, 25.8% had one or more STH. Individual prevalence rates were as follows: Ascaris lumbricoides, 16.1%; Strongyloides stercoralis, 10.5%; hookworm, 1.6%; and Trichuris trichiura, (1.6%). The prevalence of common STH (A. lumbricoides, T. trichiura, and hookworm) was higher among children aged 2–5 years than older children (31.6% versus 12.8%; P = 0.01). In terms of sanitation deficits, walking barefoot was significantly associated with STH infection (OR = 3.28; CI 95% = 1.11–12.07). Furthermore, STH-infected children more frequently had a mother who was concomitantly infected by STH than the non-STH–infected counterpart (36.4% versus 14.1%, P = 0.02). In conclusion, STH infection is highly prevalent in children from this Amazonian community despite routine deworming. Institutional health policies may include hygiene and sanitation improvements and screening/deworming of mothers to limit the dissemination of STH. Further studies are needed to address the social and epidemiological mechanics perpetuating these infections.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	adolescent	en_US
dc.subject	age distribution	en_US
dc.subject	Article	en_US
dc.subject	Ascaris lumbricoides	en_US
dc.subject	child	en_US
dc.subject	controlled study	en_US
dc.subject	environmental sanitation	en_US
dc.subject	feces analysis	en_US
dc.subject	female	en_US
dc.subject	health care policy	en_US
dc.subject	helminth	en_US
dc.subject	helminthiasis	en_US
dc.subject	hookworm	en_US
dc.subject	human	en_US
dc.subject	KATO III cell line	en_US
dc.subject	major clinical study	en_US
dc.subject	male	en_US
dc.subject	mebendazole	en_US
dc.subject	mother	en_US
dc.subject	parasite transmission	en_US
dc.subject	personal hygiene	en_US
dc.subject	Peruvian	en_US
dc.subject	prevalence	en_US
dc.subject	rural population	en_US
dc.subject	school child	en_US
dc.subject	school health service	en_US
dc.subject	screening test	en_US
dc.subject	sedimentation	en_US
dc.subject	smear	en_US
dc.subject	soil microflora	en_US
dc.subject	Strongyloides stercoralis	en_US
dc.subject	total quality management	en_US
dc.subject	Trichuris trichiura	en_US
dc.title	Soil-transmitted helminthiasis in children from a rural community taking part in a periodic deworming program in the Peruvian Amazon	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.18-1011
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645