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Malaria vector species in amazonian Peru co-occur in larval habitats but have distinct larval microbial communities

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dc.contributor.author Prussing, Catharine
dc.contributor.author Saavedra, Marlon P.
dc.contributor.author Bickersmith, Sara A.
dc.contributor.author Alava, Freddy
dc.contributor.author Guzman, Mitchel
dc.contributor.author Manrique, Edgar
dc.contributor.author Carrasco-Escobar, Gabriel
dc.contributor.author Moreno, Marta
dc.contributor.author Gamboa, Dionicia
dc.contributor.author Vinetz, Joseph M.
dc.contributor.author Conn, Jan E.
dc.date.accessioned 2019-12-06T20:57:51Z
dc.date.available 2019-12-06T20:57:51Z
dc.date.issued 2019
dc.identifier.uri https://hdl.handle.net/20.500.12866/7449
dc.description.abstract In Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source management could be a useful supplementary intervention, but to determine its feasibility, more detailed studies on the larval ecology of Ny. darlingi are essential. We conducted a multi-level study of the larval ecology of Anophelinae mosquitoes in the peri-Iquitos region of Amazonian Peru, examining the environmental characteristics of the larval habitats of four species, comparing the larval microbiota among species and habitats, and placing Ny. darlingi larval habitats in the context of spatial heterogeneity in human malaria transmission. We collected Ny. darlingi, Nyssorhynchus rangeli (formerly Anopheles rangeli), Nyssorhynchus triannulatus s.l. (formerly Anopheles triannulatus s.l.), and Nyssorhynchus sp. nr. konderi (formerly Anopheles sp. nr. konderi) from natural and artificial water bodies throughout the rainy and dry seasons. We found that, consistent with previous studies in this region and in Brazil, the presence of Ny. darlingi was significantly associated with water bodies in landscapes with more recent deforestation and lower light intensity. Nyssorhynchus darlingi presence was also significantly associated with a lower vegetation index, other Anophelinae species, and emergent vegetation. Though they were collected in the same water bodies, the microbial communities of Ny. darlingi larvae were distinct from those of Ny. rangeli and Ny. triannulatus s.l., providing evidence either for a species-specific larval microbiome or for segregation of these species in distinct microhabitats within each water body. We demonstrated that houses with more reported malaria cases were located closer to Ny. darlingi larval habitats; thus, targeted control of these sites could help ameliorate malaria risk. The co-occurrence of Ny. darlingi larvae in water bodies with other putative malaria vectors increases the potential impact of larval source management in this region. en_US
dc.language.iso eng
dc.publisher PLoS
dc.relation.ispartof urn:issn:1935-2735
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject adult en_US
dc.subject algorithm en_US
dc.subject animal en_US
dc.subject Animals en_US
dc.subject Anopheles en_US
dc.subject Anopheles darlingi en_US
dc.subject aquatic species en_US
dc.subject Article en_US
dc.subject Bacteria en_US
dc.subject bacterium en_US
dc.subject bacterium contamination en_US
dc.subject biome en_US
dc.subject Brazil en_US
dc.subject classification en_US
dc.subject controlled study en_US
dc.subject cytochrome c oxidase en_US
dc.subject deforestation en_US
dc.subject disease transmission en_US
dc.subject ecosystem en_US
dc.subject Ecosystem en_US
dc.subject female en_US
dc.subject gene amplification en_US
dc.subject genetics en_US
dc.subject genomic DNA en_US
dc.subject human en_US
dc.subject Humans en_US
dc.subject isolation and purification en_US
dc.subject larva en_US
dc.subject Larva en_US
dc.subject larval stage en_US
dc.subject light intensity en_US
dc.subject malaria en_US
dc.subject Malaria en_US
dc.subject microbial community en_US
dc.subject microbiology en_US
dc.subject microbiome en_US
dc.subject Microbiota en_US
dc.subject microflora en_US
dc.subject mosquito vector en_US
dc.subject Mosquito Vectors en_US
dc.subject nonhuman en_US
dc.subject nucleotide sequence en_US
dc.subject Nyssorhynchus rangeli en_US
dc.subject Nyssorhynchus triannulatus en_US
dc.subject Peru en_US
dc.subject pH en_US
dc.subject Plasmodium vivax en_US
dc.subject polymerase chain reaction en_US
dc.subject remote sensing en_US
dc.subject restriction fragment length polymorphism en_US
dc.subject RNA 16S en_US
dc.subject salinity en_US
dc.subject species diversity en_US
dc.subject species identification en_US
dc.subject vector control en_US
dc.subject water temperature en_US
dc.title Malaria vector species in amazonian Peru co-occur in larval habitats but have distinct larval microbial communities en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pntd.0007412
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06

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