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What is a COPD-Like Spirometry Test Result in Resource Constrained Settings?

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dc.contributor.author Gianella, Gonzalo E.
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Hurst, John R.
dc.date.accessioned 2019-12-06T21:02:55Z
dc.date.available 2019-12-06T21:02:55Z
dc.date.issued 2019
dc.identifier.uri https://hdl.handle.net/20.500.12866/7494
dc.description.abstract The diagnosis of chronic obstructive pulmonary disease (COPD), a global health problem, is challenging in resource-constrained settings. Spirometry with an obstructive pattern after the administration of bronchodilators is required for the diagnosis of COPD. Existing COPD treatment guidelines, largely derived from studies performed in populations of cigarette-smokers, recommend pharmacologic interventions with a tendency to include new-and expensive-drugs as first line agents. As the different factors that cause nonsmokers to develop COPD lead to different phenotypes of disease, COPD severity and treatment efficacy cannot be extrapolated to be the same as in the population of smokers. In so doing, current global initiatives may carry risks when trying to over simplify diagnostic approaches and push for standardization of treatment algorithms that are not context-specific. Future work to mitigate the global burden of COPD needs to address the need for new epidemiological data, especially in areas where tobacco use is less prevalent and environmental factors such as domestic air pollution is common. en_US
dc.description.sponsorship Este trabajo fue financiado por FONDECYT a través de CIENCIACTIVA/CONCYTEC, British Council, Embajada Británica y el Fondo Newton-Paulet [223-2018; 224-2018]. es_PE
dc.language.iso eng
dc.publisher Taylor and Francis
dc.relation.ispartofseries COPD
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject air pollution en_US
dc.subject Article en_US
dc.subject chronic obstructive lung disease en_US
dc.subject Chronic obstructive pulmonary disease en_US
dc.subject cigarette smoking en_US
dc.subject disease severity en_US
dc.subject environmental factor en_US
dc.subject human en_US
dc.subject low and middle-income settings en_US
dc.subject non-smoker en_US
dc.subject priority journal en_US
dc.subject spirometry en_US
dc.subject spirometry test en_US
dc.subject tobacco use en_US
dc.title What is a COPD-Like Spirometry Test Result in Resource Constrained Settings? en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1080/15412555.2019.1641794
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.07
dc.relation.issn 1541-2563


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