Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru

Rodriguez, J.; Espinoza, J.R.; Quiñones, I.; Huanca, T.; Gallegos, R.; Delgado-De-la-Flor, I.; de la Cruz Perez, A.

dc.contributor.author	Gallegos, R.
dc.contributor.author	Rodriguez, J.
dc.contributor.author	Quiñones, I.
dc.contributor.author	Delgado-De-la-Flor, I.
dc.contributor.author	Huanca, T.
dc.contributor.author	de la Cruz Perez, A.
dc.contributor.author	Espinoza, J.R.
dc.date.accessioned	2019-12-06T21:02:56Z
dc.date.available	2019-12-06T21:02:56Z
dc.date.issued	2019
dc.identifier.uri	https://hdl.handle.net/20.500.12866/7502
dc.description.abstract	The objective of this study was to identify genetic single nucleotide polymorphisms (SNPs) in the coding region of the KRTAP11.1 gene from the Suri alpaca population from Puno, Peru. Genomic DNA (n = 119) was used to amplify the 636 bp fragment of the coding region from the KRTAP11.1 gene. The polymerase chain reaction products of the KRTAP11.1 gene were sequenced by both strands and polymorphism type SNPs were identified. All SNPs (n = 3) were in Hardy-Weinberg equilibrium and had a high level of genotypic linkage disequilibrium with the presence of two haplotypes. All genetic polymorphisms generate non-synonymous amino acids changes: SNP 110 T>G (Ser>Ala), SNP 363 T>G (Phe>Cys) and SNP 375 A>C (Tyr>Ser). The results indicated the presence of moderate genetic diversity in the coding region of the KRTAP11.1 gene from the Suri alpaca population.	en_US
dc.description.sponsorship	Este trabajo fue financiado por PROCYT-CONCYTEC en el marco del proyecto "Generación de marcadores tipo SNPs en genes codantes de proteínas componentes de la fibra y su uso en selección genética y filogenia de la alpaca”.	es_PE
dc.language.iso	eng
dc.publisher	Kasetsart University Research and Development Institute
dc.relation.ispartofseries	Agriculture and Natural Resources
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Alpaca	en_US
dc.subject	KAP11.1 gene	en_US
dc.subject	Keratin associated protein	en_US
dc.subject	Single nucleotide polymorphisms (SNPs)	en_US
dc.subject	Suri	en_US
dc.title	Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.34044/j.anres.2019.53.1.15
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#4.01.01
dc.relation.issn	2452-316X