Characterization of ESBL-Producing Salmonella enterica Serovar Infantis Infection in Humans, Lima, Peru.

Jacobs, Jan; García Apac, Coralith Marlinda; Network, For The Salmoiber Cyted; Ochoa Woodell, Theresa Jean; Astocondor, Lizeth; Hinostroza, Noemi

dc.contributor.author	García Apac, Coralith Marlinda
dc.contributor.author	Hinostroza, Noemi
dc.contributor.author	Astocondor, Lizeth
dc.contributor.author	Ochoa Woodell, Theresa Jean
dc.contributor.author	Jacobs, Jan
dc.contributor.author	Network, For The Salmoiber Cyted
dc.date.accessioned	2019-12-06T21:02:57Z
dc.date.available	2019-12-06T21:02:57Z
dc.date.issued	2019
dc.identifier.uri	https://hdl.handle.net/20.500.12866/7519
dc.description.abstract	Salmonella enterica serovar Infantis is causing an increasing number of infections worldwide. Our aim was to describe the characteristics of S. enterica serovar Infantis among patients attended in a hospital of Lima, Peru. Fifty cases of salmonellosis were seen during October 2015–May 2017; Salmonella Infantis was detected in 36% (n = 18) of them, displacing Enteritidis and Typhimurium (n = 13, 26%, each). Seventeen cases caused by Salmonella Infantis were presented as diarrheal illnesses; only one extraintestinal case (bacteremia) was seen in a 1-year-old infant. This serovar is resistant to multiple groups of antimicrobials, showing only fully susceptibility to carbapenems. Compared with Infantis, other serovars analyzed (mainly Enteritidis and Typhimurium) showed a lower frequency of resistance to antimicrobials such as trimethoprim–sulfamethoxazole, ampicillin, and chloramphenicol. The antibiotic with the highest frequency of resistance was ciprofloxacin. Further studies are needed to evaluate the routes of transmission and measures of control of this multidrug-resistant Salmonella.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	ampicillin	en_US
dc.subject	antibiotic resistance	en_US
dc.subject	Article	en_US
dc.subject	bacteremia	en_US
dc.subject	bacterium detection	en_US
dc.subject	bacterium isolation	en_US
dc.subject	carbapenem	en_US
dc.subject	child	en_US
dc.subject	chloramphenicol	en_US
dc.subject	ciprofloxacin	en_US
dc.subject	cotrifamole	en_US
dc.subject	diarrhea	en_US
dc.subject	disease burden	en_US
dc.subject	disk diffusion	en_US
dc.subject	Enterobacteriaceae	en_US
dc.subject	extended spectrum beta lactamase producing Salmonella enterica serovar Infantis	en_US
dc.subject	gene	en_US
dc.subject	gene identification	en_US
dc.subject	human	en_US
dc.subject	invA gene	en_US
dc.subject	multiplex polymerase chain reaction	en_US
dc.subject	nonhuman	en_US
dc.subject	Peru	en_US
dc.subject	preschool child	en_US
dc.subject	prospective study	en_US
dc.subject	Salmonella enterica serovar Enteritidis	en_US
dc.subject	Salmonella enterica serovar Typhimurium	en_US
dc.subject	salmonellosis	en_US
dc.subject	school child	en_US
dc.title	Characterization of ESBL-Producing Salmonella enterica Serovar Infantis Infection in Humans, Lima, Peru.	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.19-0213
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645