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dc.contributor.author | Emuron, Dennis | |
dc.contributor.author | Siddharthan, Trishul | |
dc.contributor.author | Morgan, Brooks | |
dc.contributor.author | Pollard, Suzanne L. | |
dc.contributor.author | Grigsby, Matthew R. | |
dc.contributor.author | Goodman, Dina | |
dc.contributor.author | Chowdhury, Muhammad | |
dc.contributor.author | Rubinstein, Adolfo | |
dc.contributor.author | Irazola, Vilma | |
dc.contributor.author | Gutierrez, Laura | |
dc.contributor.author | Miranda, J. Jaime | |
dc.contributor.author | Bernabé Ortiz, Antonio | |
dc.contributor.author | Alam, Dewan | |
dc.contributor.author | Kirenga, Bruce | |
dc.contributor.author | Jones, Rupert | |
dc.contributor.author | van Gemert, Frederik | |
dc.contributor.author | Checkley, William | |
dc.date.accessioned | 2019-12-06T21:04:44Z | |
dc.date.available | 2019-12-06T21:04:44Z | |
dc.date.issued | 2019 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/7591 | |
dc.description.abstract | CONTEXT: Observational studies investigating household air pollution (HAP) exposure to biomass fuel smoke as a risk factor for pulmonary tuberculosis have reported inconsistent results. OBJECTIVE: To evaluate the association between HAP exposure and the prevalence of self-reported previous pulmonary tuberculosis. DESIGN: We analyzed pooled data including 12,592 individuals from five population-based studies conducted in Latin America, East Africa, and Southeast Asia from 2010 to 2015. We used multivariable logistic regression to model the association between HAP exposure and self-reported previous pulmonary tuberculosis adjusted for age, sex, tobacco smoking, body mass index, secondary education, site and country of residence. RESULTS: Mean age was 54.6 years (range of mean age across settings 43.8-59.6 years) and 48.6% were women (range of % women 38.3-54.5%). The proportion of participants reporting HAP exposure was 38.8% (range in % HAP exposure 0.48-99.4%). Prevalence of previous pulmonary tuberculosis was 2.7% (range of prevalence 0.6-6.9%). While participants with previous pulmonary tuberculosis had a lower pre-bronchodilator FEV1 (mean - 0.7 SDs, 95% CI - 0.92 to - 0.57), FVC (- 0.52 SDs, 95% CI - 0.69 to - 0.33) and FEV1/FVC (- 0.59 SDs, 95% CI - 0.76 to - 0.43) as compared to those who did not, we did not find an association between HAP exposure and previous pulmonary tuberculosis (adjusted odds ratio = 0.86; 95% CI 0.56-1.32). CONCLUSIONS: There was no association between HAP exposure and self-reported previous pulmonary tuberculosis in five population-based studies conducted worldwide. | en_US |
dc.language.iso | eng | |
dc.publisher | Springer | |
dc.relation.ispartofseries | Lung | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | Biomass fuel | en_US |
dc.subject | Cross-sectional study | en_US |
dc.subject | Tuberculosis burden | en_US |
dc.title | Lack of an Association Between Household Air Pollution Exposure and Previous Pulmonary Tuberculosis. | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1007/s00408-019-00275-8 | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.02.07 | |
dc.relation.issn | 1432-1750 |
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