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Risk scores for type 2 diabetes mellitus in Latin America: a systematic review of population-based studies.

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dc.contributor.author Carrillo-Larco, R. M.
dc.contributor.author Aparcana-Granda, D. J.
dc.contributor.author Mejia, J. R.
dc.contributor.author Barengo, N. C.
dc.contributor.author Bernabe-Ortiz, A.
dc.date.accessioned 2019-12-06T21:04:44Z
dc.date.available 2019-12-06T21:04:44Z
dc.date.issued 2019
dc.identifier.uri https://hdl.handle.net/20.500.12866/7595
dc.description.abstract AIM: To summarize the evidence on diabetes risk scores for Latin American populations. METHODS: A systematic review was conducted (CRD42019122306) looking for diagnostic and prognostic models for type 2 diabetes mellitus among randomly selected adults in Latin America. Five databases (LILACS, Scopus, MEDLINE, Embase and Global Health) were searched. type 2 diabetes mellitus was defined using at least one blood biomarker and the reports needed to include information on the development and/or validation of a multivariable regression model. Risk of bias was assessed using the PROBAST guidelines. RESULTS: Of the 1500 reports identified, 11 were studied in detail and five were included in the qualitative analysis. Two reports were from Mexico, two from Peru and one from Brazil. The number of diabetes cases varied from 48 to 207 in the derivations models, and between 29 and 582 in the validation models. The most common predictors were age, waist circumference and family history of diabetes, and only one study used oral glucose tolerance test as the outcome. The discrimination performance across studies was ~ 70% (range: 66-72%) as per the area under the receiving-operator curve, the highest metric was always the negative predictive value. Sensitivity was always higher than specificity. CONCLUSION: There is no evidence to support the use of one risk score throughout Latin America. The development, validation and implementation of risk scores should be a research and public health priority in Latin America to improve type 2 diabetes mellitus screening and prevention. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartof urn:issn:1464-5491
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Brazil en_US
dc.subject diabetes risk score en_US
dc.subject Embase en_US
dc.subject family history en_US
dc.subject glucose en_US
dc.subject hemoglobin A1c en_US
dc.subject human en_US
dc.subject Medline en_US
dc.subject Mexico en_US
dc.subject non insulin dependent diabetes mellitus en_US
dc.subject oral glucose tolerance test en_US
dc.subject Peru en_US
dc.subject practice guideline en_US
dc.subject predictive value en_US
dc.subject public health problem en_US
dc.subject qualitative analysis en_US
dc.subject Review en_US
dc.subject Scopus en_US
dc.subject South and Central America en_US
dc.subject systematic review en_US
dc.subject waist circumference en_US
dc.title Risk scores for type 2 diabetes mellitus in Latin America: a systematic review of population-based studies. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1111/dme.14114
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.18
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.27

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