Cutaneous leishmaniasis (CL) is an ulcerative skin parasitic disease common in people living in tropical regions and travelers(1) . Lesions characteristics (e.g., self-healing and treatment response) are extremely variable. Diagnosis can be challenging when the lesion is in an advanced stage and can be confused with other pathologies. On histology, epidermal and dermal abnormalities have been described(2) . Panniculitis has been reported as an important feature to distinguish CL from other dermatological lesions(3) . High-frequency ultrasound is a non-invasive imaging tool that depicts tissues with high definition(4) . We aim to describe the ultrasound morphology of confirmed cases of CL and correlation with the reported histopathological characteristics.