Universidad Peruana Cayetano Heredia

Plasmodium vivax hospitalizations in a monoendemic malaria region: severe vivax malaria?

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dc.contributor.author Quispe, Antonio M.
dc.contributor.author Pozo, Edwar
dc.contributor.author Guerrero, Edith
dc.contributor.author Durand, Salomón
dc.contributor.author Baldeviano, G. Christian
dc.contributor.author Edgel, Kimberly A.
dc.contributor.author Graf, Paul C. F.
dc.contributor.author Lescano Guevara, Andres Guillermo
dc.date.accessioned 2020-06-10T18:11:31Z
dc.date.available 2020-06-10T18:11:31Z
dc.date.issued 2014
dc.identifier.uri https://hdl.handle.net/20.500.12866/7970
dc.description.abstract Severe malaria caused by Plasmodium vivax is no longer considered rare. To describe its clinical features, we performed a retrospective case control study in the subregion of Luciano Castillo Colonna, Piura, Peru, an area with nearly exclusive vivax malaria transmission. Severe cases and the subset of critically ill cases were compared with a random set of uncomplicated malaria cases (1:4). Between 2008 and 2009, 6,502 malaria cases were reported, including 106 hospitalized cases, 81 of which fit the World Health Organization definition for severe malaria. Of these 81 individuals, 28 individuals were critically ill (0.4%, 95% confidence interval = 0.2-0.6%) with severe anemia (57%), shock (25%), lung injury (21%), acute renal failure (14%), or cerebral malaria (11%). Two potentially malaria-related deaths occurred. Compared with uncomplicated cases, individuals critically ill were older (38 versus 26 years old, P < 0.001), but similar in other regards. Severe vivax malaria monoinfection with critical illness is more common than previously thought. en_US
dc.language.iso eng
dc.publisher American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adult en_US
dc.subject Age Factors en_US
dc.subject Aged en_US
dc.subject Aged, 80 and over en_US
dc.subject Anemia/diagnosis/etiology/parasitology/pathology en_US
dc.subject Brain/parasitology/pathology en_US
dc.subject Case-Control Studies en_US
dc.subject Child, Preschool en_US
dc.subject Critical Illness en_US
dc.subject Endemic Diseases en_US
dc.subject Female en_US
dc.subject Hospitalization/statistics & numerical data en_US
dc.subject Humans en_US
dc.subject Lung Injury/diagnosis/etiology/parasitology/pathology en_US
dc.subject Malaria, Vivax/complications/diagnosis/parasitology/pathology en_US
dc.subject Male en_US
dc.subject Middle Aged en_US
dc.subject Peru en_US
dc.subject Plasmodium vivax/pathogenicity en_US
dc.subject Renal Insufficiency, Chronic/diagnosis/etiology/parasitology/pathology en_US
dc.subject Retrospective Studies en_US
dc.subject Severity of Illness Index en_US
dc.subject Shock/diagnosis/etiology/parasitology/pathology en_US
dc.title Plasmodium vivax hospitalizations in a monoendemic malaria region: severe vivax malaria? en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.12-0610
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn 1476-1645


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