Relative undernourishment and food insecurity associations with Plasmodium falciparum among Batwa pygmies in Uganda: evidence from a cross-sectional survey

Lwasa, Shuaib; Harper, Sherilee L.; Namanya, Didacus Bambaiha; Ford, J.D.; Llanos Cuentas, Elmer Alejandro; Edge, V.L.; Donnelly, Blánaid; Lewnard, Joseph A.; Cárcamo Cavagnaro, César Paul Eugenio; Berrang-Ford, Lea; Patterson, Kaitlin A.; Kulkarni, Manisha A.; Ogden, Nicholas H.

dc.contributor.author	Lewnard, Joseph A.
dc.contributor.author	Berrang-Ford, Lea
dc.contributor.author	Lwasa, Shuaib
dc.contributor.author	Namanya, Didacus Bambaiha
dc.contributor.author	Patterson, Kaitlin A.
dc.contributor.author	Donnelly, Blánaid
dc.contributor.author	Kulkarni, Manisha A.
dc.contributor.author	Harper, Sherilee L.
dc.contributor.author	Ogden, Nicholas H.
dc.contributor.author	Cárcamo Cavagnaro, César Paul Eugenio
dc.contributor.author	Ford, J.D.
dc.contributor.author	Edge, V.L.
dc.contributor.author	Llanos Cuentas, Elmer Alejandro
dc.date.accessioned	2020-06-10T18:11:36Z
dc.date.available	2020-06-10T18:11:36Z
dc.date.issued	2014
dc.identifier.uri	https://hdl.handle.net/20.500.12866/8018
dc.description.abstract	Although malnutrition and malaria co-occur among individuals and populations globally, effects of nutritional status on risk for parasitemia and clinical illness remain poorly understood. We investigated associations between Plasmodium falciparum infection, nutrition, and food security in a cross-sectional survey of 365 Batwa pygmies in Kanungu District, Uganda in January of 2013. We identified 4.1% parasite prevalence among individuals over 5 years old. Severe food insecurity was associated with increased risk for positive rapid immunochromatographic test outcome (adjusted relative risk [ARR] = 13.09; 95% confidence interval [95% CI] = 2.23-76.79). High age/sex-adjusted mid-upper arm circumference was associated with decreased risk for positive test among individuals who were not severely food-insecure (ARR = 0.37; 95% CI = 0.19-0.69). Within Batwa pygmy communities, where malnutrition and food insecurity are common, individuals who are particularly undernourished or severely food-insecure may have elevated risk for P. falciparum parasitemia. This finding may motivate integrated control of malaria and malnutrition in low-transmission settings.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Food Supply	en_US
dc.subject	Adolescent	en_US
dc.subject	Adult	en_US
dc.subject	Child	en_US
dc.subject	Cross-Sectional Studies	en_US
dc.subject	Ethnic Groups	en_US
dc.subject	Female	en_US
dc.subject	Humans	en_US
dc.subject	Malaria, Falciparum/complications/ethnology/parasitology	en_US
dc.subject	Male	en_US
dc.subject	Malnutrition/complications/ethnology/parasitology	en_US
dc.subject	Middle Aged	en_US
dc.subject	Nutritional Status	en_US
dc.subject	Parasitemia/complications/ethnology/parasitology	en_US
dc.subject	Plasmodium falciparum/physiology	en_US
dc.subject	Prevalence	en_US
dc.subject	Uganda/epidemiology	en_US
dc.title	Relative undernourishment and food insecurity associations with Plasmodium falciparum among Batwa pygmies in Uganda: evidence from a cross-sectional survey	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.13-0422
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645