DSpace Repository

Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals

Show simple item record

dc.contributor.author Ruiz-Linares, Andrés
dc.contributor.author Adhikari, Kaustubh
dc.contributor.author Acuña-Alonzo, Victor
dc.contributor.author Quinto-Sanchez, Mirsha
dc.contributor.author Jaramillo, Claudia
dc.contributor.author Arias, William
dc.contributor.author Fuentes, Macarena
dc.contributor.author Pizarro, María
dc.contributor.author Everardo, Paola
dc.contributor.author de Avila, Francisco
dc.contributor.author Gómez-Valdés, Jorge
dc.contributor.author León-Mimila, Paola
dc.contributor.author Hunemeier, Tábita
dc.contributor.author Ramallo, Virginia
dc.contributor.author Silva de Cerqueira, Caio C.
dc.contributor.author Burley, Mari-Wyn
dc.contributor.author Konca, Esra
dc.contributor.author de Oliveira, Marcelo Zagonel
dc.contributor.author Veronez, Mauricio Roberto
dc.contributor.author Rubio-Codina, Marta
dc.contributor.author Attanasio, Orazio
dc.contributor.author Gibbon, Sahra
dc.contributor.author Ray, Nicolas
dc.contributor.author Gallo López-Aliaga, Carla Maria
dc.contributor.author Poletti, Giovanni
dc.contributor.author Rosique, Javier
dc.contributor.author Schuler-Faccini, Lavinia
dc.contributor.author Salzano, Francisco M.
dc.contributor.author Bortolini, Maria-Cátira
dc.contributor.author Canizales-Quinteros, Samuel
dc.contributor.author Rothhammer, Francisco
dc.contributor.author Bedoya, Gabriel
dc.contributor.author Balding, David
dc.contributor.author Gonzalez-José, Rolando
dc.date.accessioned 2020-06-10T18:12:16Z
dc.date.available 2020-06-10T18:12:16Z
dc.date.issued 2014
dc.identifier.uri https://hdl.handle.net/20.500.12866/8084
dc.description.abstract The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification. We estimated individual ancestry proportions in a sample of 7,342 subjects ascertained in five countries (Brazil, Chile, Colombia, Mexico and Peru). These individuals were also characterized for a range of physical appearance traits and for self-perception of ancestry. The geographic distribution of admixture proportions in this sample reveals extensive population structure, illustrating the continuing impact of demographic history on the genetic diversity of Latin America. Significant ancestry effects were detected for most phenotypes studied. However, ancestry generally explains only a modest proportion of total phenotypic variation. Genetically estimated and self-perceived ancestry correlate significantly, but certain physical attributes have a strong impact on self-perception and bias self-perception of ancestry relative to genetically estimated ancestry. en_US
dc.language.iso eng
dc.publisher Public Library of Science
dc.relation.ispartofseries PLoS Genetics
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Genetic Variation en_US
dc.subject Genetics, Population en_US
dc.subject Phenotype en_US
dc.subject Biological Evolution en_US
dc.subject Ethnic Groups/genetics en_US
dc.subject Female en_US
dc.subject Geography en_US
dc.subject Humans en_US
dc.subject Latin America en_US
dc.subject Male en_US
dc.subject Quantitative Trait, Heritable en_US
dc.subject Self Concept en_US
dc.title Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pgen.1004572
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.07
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.03
dc.relation.issn 1553-7404

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/restrictedAccess Except where otherwise noted, this item's license is described as info:eu-repo/semantics/restrictedAccess

Search DSpace


My Account