Universidad Peruana Cayetano Heredia

Adherence to pharmacotherapy and medication-related beliefs in patients with hypertension in Lima, Peru

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dc.contributor.author Fernandez-Arias, Marta
dc.contributor.author Acuna-Villaorduna, Ana
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Diez-Canseco Montero, Francisco
dc.contributor.author Málaga Rodríguez, Germán Javier
dc.date.accessioned 2020-06-10T18:12:20Z
dc.date.available 2020-06-10T18:12:20Z
dc.date.issued 2014
dc.identifier.uri https://hdl.handle.net/20.500.12866/8110
dc.description.abstract OBJECTIVE: To characterize adherence to pharmacological medication and beliefs towards medication in a group of patients with hypertension in a large national hospital. MATERIALS AND METHODS: Cross-sectional survey among patients with hypertension attending the outpatient clinic of a large national hospital. Exposure of interest was the patient's beliefs towards general medication and antihypertensive drugs, i.e. beliefs of harm, overuse, necessity and concern, measured using the Beliefs about Medication questionnaire. Main outcome was adherence measured using the Morisky Medication Adherence Scale-8. Multivariate analysis was conducted using Poisson distribution logistic regression, prevalence ratios and 95% confidence intervals were calculated. RESULTS: Data from 115 participants, 67% females and mean age 62.7 years were analyzed. Low adherence was found in 57.4%. Highest scores were on the ideas of necessity and one of the most rated statements was "physicians would prescribe less medication if they spent more time with patients". Beliefs of harm about medications and concerns about antihypertensive drugs were higher in the low adherence group (p<0.01). Those who scored higher on ideas of harm were 52% less likely of being high adherents (PR 0.48; 95% CI 0.25-0.93) and those with higher scores on concerns were 41% less likely of being high adherents (PR 0.59; 95% CI 0.39-0.91). Patients whose ideas of necessity outweighed their concerns were more likely to be adherent (PR 2.65; 95% CI 1.21-5.81). CONCLUSIONS: Low adherence to antihypertensive medication is common. High scores on ideas of harm, concern and a high necessity-concern differential were predictors of medication adherence. en_US
dc.language.iso eng
dc.publisher Public Library of Science
dc.relation.ispartofseries PLoS ONE
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Aged en_US
dc.subject Antihypertensive Agents/therapeutic use en_US
dc.subject Cross-Sectional Studies en_US
dc.subject Culture en_US
dc.subject Female en_US
dc.subject Health Knowledge, Attitudes, Practice en_US
dc.subject Health Surveys en_US
dc.subject Humans en_US
dc.subject Hypertension/drug therapy/psychology en_US
dc.subject Male en_US
dc.subject Medication Adherence/psychology en_US
dc.subject Middle Aged en_US
dc.subject Peru en_US
dc.title Adherence to pharmacotherapy and medication-related beliefs in patients with hypertension in Lima, Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pone.0112875
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.05
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#5.01.00
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.27
dc.relation.issn 1932-6203


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