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Taenia solium infection in Peru: a collaboration between Peace Corps Volunteers and researchers in a community based study

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dc.contributor.author Watts, Nathaniel S.
dc.contributor.author Pajuelo Travezaño, Monica Jhenny
dc.contributor.author Clark, Taryn
dc.contributor.author Loader, Maria-Cristina I.
dc.contributor.author Verastegui Pimentel, Manuela Renee
dc.contributor.author Sterling, Charles
dc.contributor.author Friedland, Jon S.
dc.contributor.author García Lescano, Héctor Hugo
dc.contributor.author Gilman, Robert Hugh
dc.date.accessioned 2020-06-10T18:12:20Z
dc.date.available 2020-06-10T18:12:20Z
dc.date.issued 2014
dc.identifier.uri https://hdl.handle.net/20.500.12866/8111
dc.description.abstract Background: Neurocysticercosis is a leading cause of seizures and epilepsy in most of the world, and it occurs when Taenia solium larval cysts infect the central nervous system. T. solium tapeworm infection is endemic in much of Peru, but there are scarce data on the prevalence in many rural highland communities where it is likely to be hyper-endemic. Peace Corps Volunteers live and work in these communities; however, to our knowledge, they have not been used to facilitate public health research. Materials and Methods: We utilized Peace Corps Volunteers to estimate the prevalence of T. solium tapeworm infection in seven rural communities in northern Peru. A convenience non-random sampling frame was used. Peace Corps Volunteers facilitated the collection of stool samples (N = 2,328), which were analyzed by sedimentation and microscopy. Niclosamide treatment and purgation preceded species identification, which was done by PCR-REA. Results: Taenia sp. egg-positive stool samples were found in three of the seven communities we surveyed. The overall prevalence of Taenia sp. egg positivity was 2.1% (49/2,328) (95% CI = 1.6–2.8%) with prevalence up to 4.3% (42/977) (95% CI = 3.1–5.8%) by community. All 34 of the specimens tested by PCR-REA were T. solium. The overall prevalence of T. solium tapeworm infection was 1.5% (34/2,328) (95% CI = 1.0–2.0%). Prevalence up to 2.9% (28/977) (95% CI = 1.9–4.1%) by community was observed. Conclusion/Significance: This study recorded high T. solium tapeworm prevalence, and identified hyper-endemic rural communities. It demonstrates that synergy between researchers and Peace Corps Volunteers can be an effective means to conducting large-scale, community-based studies in remote areas of Peru. en_US
dc.language.iso eng
dc.publisher Public Library of Science
dc.relation.ispartofseries PLoS ONE
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adolescent en_US
dc.subject Adult en_US
dc.subject Animals en_US
dc.subject Anticestodal Agents/administration & dosage en_US
dc.subject Child en_US
dc.subject Cooperative Behavior en_US
dc.subject Cross-Sectional Studies en_US
dc.subject Feces/parasitology en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Neurocysticercosis/drug therapy/epidemiology/parasitology en_US
dc.subject Niclosamide/administration & dosage en_US
dc.subject Peace Corps en_US
dc.subject Peru/epidemiology en_US
dc.subject Prevalence en_US
dc.subject Research Personnel en_US
dc.subject Rural Population en_US
dc.subject Taenia solium/drug effects/isolation & purification en_US
dc.subject United States en_US
dc.subject Volunteers en_US
dc.subject Young Adult en_US
dc.title Taenia solium infection in Peru: a collaboration between Peace Corps Volunteers and researchers in a community based study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pone.0113239
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.07
dc.relation.issn 1932-6203

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