DSpace Repository

Severe COVID-19 during pregnancy and possible vertical transmission

Show simple item record

dc.contributor.author Alzamora, Maria Claudia
dc.contributor.author Paredes, Tania
dc.contributor.author Caceres, David
dc.contributor.author Webb, Camille M.
dc.contributor.author Valdez, Luis M.
dc.contributor.author La Rosa, Mauricio
dc.date.accessioned 2020-07-14T00:00:54Z
dc.date.available 2020-07-14T00:00:54Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8222
dc.description.abstract There are few cases of pregnant women with novel corona virus 2019 (COVID-19) in the literature, most of them with a mild illness course. There is limited evidence about in utero infection and early positive neonatal testing. A 41-year-old G3P2 with a history of previous cesarean deliveries and diabetes mellitus presented with a 4-day history of malaise, low-grade fever, and progressive shortness of breath. A nasopharyngeal swab was positive for COVID-19, COVID-19 serology was negative. The patient developed respiratory failure requiring mechanical ventilation on day 5 of disease onset. The patient underwent a cesarean delivery, and neonatal isolation was implemented immediately after birth, without delayed cord clamping or skin-to-skin contact. The neonatal nasopharyngeal swab, 16 hours after delivery, was positive for severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) real-time polymerase chain reaction (RT-PCR), and immunoglobulin (Ig)-M and IgG for SARS-CoV-2 were negative. Maternal IgM and IgG were positive on postpartum day 4 (day 9 after symptom onset). We report a severe presentation of COVID-19 during pregnancy. To our knowledge, this is the earliest reported positive PCR in the neonate, raising the concern for vertical transmission. We suggest pregnant women should be considered as a high-risk group and minimize exposures for these reasons. en_US
dc.language.iso eng
dc.publisher Thieme Publishing Group
dc.relation.ispartof urn:issn:2157-7005
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject COVID-19 en_US
dc.subject coronavirus en_US
dc.subject neonate en_US
dc.subject pregnancy en_US
dc.title Severe COVID-19 during pregnancy and possible vertical transmission en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1055/s-0040-1710050

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/restrictedAccess Except where otherwise noted, this item's license is described as info:eu-repo/semantics/restrictedAccess

Search DSpace


My Account