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Actividad antimicrobiana de Streptomyces sp. 6E3 aislado de concentrado de mineral

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dc.contributor.author Ampuero, Angela
dc.contributor.author Rojas, Rosario
dc.contributor.author Ruiz, Candy
dc.contributor.author Hurtado Custodio, Jasmin Elena
dc.date.accessioned 2020-07-14T00:00:54Z
dc.date.available 2020-07-14T00:00:54Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8224
dc.description.abstract The objectives of this study were to determine the antimicrobial activity of a culture of Streptomyces sp. 6E3 isolated from minerals against different pathogenic strains, to produce an extract and to estimate the minimum inhibitory concentration (MIC) of the fractions against methicillin-resistant Staphylococcus aureus (MRSA). Streptomyces sp. 6E3 showed antimicrobial activity primarily against Staphylococcus aureus (S. aureus). Five of the six fractions presented antimicrobial activity and the most effective gave a MIC of 0.88 ug / mL against S. aureus ATCC 33862, 0.44 ug / mL against S. aureus ATCC 43300 and 1.76 ug / mL vs. a S. aureus MRSA strain. Streptomyces sp. 6E3 has an antimicrobial potential against S. aureus strains resistant to methicillin and non-resistant, being of interest carrying out of more studies on its active metabolites. en_US
dc.description.abstract El objetivo de este estudio fue determinar la actividad antimicrobiana de un cultivo de Streptomyces sp. 6E3 aislado de minerales frente a diferentes cepas patógenas, producir un extracto y estimar la concentración mínima inhibitoria (CMI) de las fracciones contra Staphylococcus aureus resistente a meticilina (SARM). La cepa Streptomyces sp. 6E3 mostró actividad antimicrobiana principalmente contra Staphylococcus aureus (S. aureus). Cinco de las seis fracciones presentaron actividad antimicrobiana y la más efectiva dio una CMI de 0,88 ug/mL frente a S. aureus ATCC 33862, 0,44 ug/mL frente a S. aureus ATCC 43300 y 1,76 ug/mL frente a S. aureus cepa SARM. Streptomyces sp. 6E3 tiene un potencial antimicrobiano frente a cepas de S. aureus resistentes a meticilina y no resistentes, siendo de interés la realización de más estudios sobre sus metabolitos activos. es_PE
dc.language.iso spa
dc.language.iso eng
dc.publisher Instituto Nacional de Salud
dc.relation.ispartofseries Revista Peruana de Medicina Experimental y Salud Pública
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Streptomyces es_PE
dc.subject Minerales es_PE
dc.subject Agentes Antiinfecciosos es_PE
dc.subject Extractos Celulares es_PE
dc.subject Bacteria es_PE
dc.subject Staphylococcus aureus es_PE
dc.subject Productos Biológicos es_PE
dc.subject Pruebas de Sensibilidad Microbiana es_PE
dc.title Actividad antimicrobiana de Streptomyces sp. 6E3 aislado de concentrado de mineral es_PE
dc.title.alternative Streptomyces sp. 6E3 antimicrobial activity isolated from mineral concentrate en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.17843/rpmesp.2020.371.4505
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1726-4642


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