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Community-acquired pneumonia in critically ill very old patients: A growing problem

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dc.contributor.author Cillóniz, C.
dc.contributor.author Dominedò, C.
dc.contributor.author Pericàs, J.M.
dc.contributor.author Rodriguez-Hurtado, D.
dc.contributor.author Torres, A.
dc.date.accessioned 2020-07-14T00:01:03Z
dc.date.available 2020-07-14T00:01:03Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8264
dc.description.abstract Very old (aged ≥80 years) adults constitute an increasing proportion of the global population. Currently, this subgroup of patients represents an important percentage of patients admitted to the intensive care unit. Community-acquired pneumonia (CAP) frequently affects very old adults. However, there are no specific recommendations for the management of critically ill very old CAP patients. Multiple morbidities, polypharmacy, immunosenescence and frailty contribute to an increased risk of pneumonia in this population. CAP in critically ill very old patients is associated with higher short-and long-term mortality; however, because of its uncommon presentation, diagnosis can be very difficult. Management of critically ill very old CAP patients should be guided by their baseline characteristics, clinical presentation and risk factors for multidrug-resistant pathogens. Hospitalisation in intermediate care may be a good option for critical ill very old CAP patients who do not require invasive procedures and for whom intensive care is questionable in terms of benefit. en_US
dc.language.iso eng
dc.publisher European Respiratory Society
dc.relation.ispartofseries European Respiratory Review
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject mortality en_US
dc.subject aged en_US
dc.subject human en_US
dc.subject incidence en_US
dc.subject risk factor en_US
dc.subject Acinetobacter en_US
dc.subject amoxicillin en_US
dc.subject amoxicillin plus clavulanic acid en_US
dc.subject antibody response en_US
dc.subject B lymphocyte en_US
dc.subject cellular immunity en_US
dc.subject cephalosporin en_US
dc.subject chemokine en_US
dc.subject ciprofloxacin en_US
dc.subject clarithromycin en_US
dc.subject clinical feature en_US
dc.subject community acquired pneumonia en_US
dc.subject comorbidity en_US
dc.subject corticosteroid en_US
dc.subject coughing en_US
dc.subject critically ill patient en_US
dc.subject cytokine en_US
dc.subject decision making en_US
dc.subject doxycycline en_US
dc.subject Escherichia coli en_US
dc.subject fever en_US
dc.subject frailty en_US
dc.subject hospitalization en_US
dc.subject humoral immunity en_US
dc.subject immunoglobulin A en_US
dc.subject immunoglobulin G en_US
dc.subject immunosenescence en_US
dc.subject inflammation en_US
dc.subject intensive care unit en_US
dc.subject Klebsiella pneumoniae en_US
dc.subject levofloxacin en_US
dc.subject long term care en_US
dc.subject lower respiratory tract infection en_US
dc.subject macrophage en_US
dc.subject morbidity en_US
dc.subject moxifloxacin en_US
dc.subject natural killer cell en_US
dc.subject neutrophil en_US
dc.subject penicillin G en_US
dc.subject polypharmacy en_US
dc.subject public health en_US
dc.subject quality of life en_US
dc.subject Review en_US
dc.subject Streptococcus pneumoniae en_US
dc.subject thorax pain en_US
dc.subject treatment failure en_US
dc.subject very elderly en_US
dc.title Community-acquired pneumonia in critically ill very old patients: A growing problem en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1183/16000617.0126-2019
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.07
dc.relation.issn 1600-0617


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