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Sampling and processing blood samples within the South American Youth/Child cARdiovascular and Environmental (SAYCARE) Study

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dc.contributor.author López, Graciela
dc.contributor.author Assali Serruya, Raphael
dc.contributor.author Barchuk, Magalí
dc.contributor.author Gaitan-Charry, Diego
dc.contributor.author Torres-Leal, Francisco Leonardo
dc.contributor.author Moreno, Luis Alberto
dc.contributor.author Delgado, Carlos Alberto
dc.contributor.author Barbosa Carvalho, Heráclito
dc.contributor.author De Moraes, Augusto César Ferreira
dc.contributor.author Berg, Gabriela
dc.date.accessioned 2020-07-14T00:02:32Z
dc.date.available 2020-07-14T00:02:32Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8331
dc.description.abstract Obesity and overweight in children and adolescents is increasing rapidly worldwide; however, scarce data have been reported from South America countries. With the purpose of assessing hyperlipidemia, insulin resistance and chronic inflammation, the evaluation of blood biomarkers such as glucose, lipoproteins and chronic inflammation proteins is required. In the context of the SAYCARE study, in children and adolescents (3 to 18 years) from seven South American cities, our aim was to assess the impact of pre analytical conditions on different biomarkers evaluated in 474 fresh serum samples, in different country centers. We also evaluated the stability according to time and frozen storage within this study across the concordance of the results obtained from the 49 blood samples measured in three different centers. Significant correlations as well as concordance were observed in TG, Total-C, HDL-C and glucose between Buenos Aires and São Paulo. The samples evaluated in Teresina and São Paulo presented similar results, with exception of total cholesterol. We observed acceptable concordance between Buenos Aires vs São Paulo and Teresina vs São Paulo, suggesting that samples could be processed in each of these centers. This concordance is a consequence of the strict pre analytical conditions previously established in the SAYCARE study. en_US
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartof urn:issn:2045-2322
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject UNAVAILABLE en_US
dc.title Sampling and processing blood samples within the South American Youth/Child cARdiovascular and Environmental (SAYCARE) Study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1038/s41598-020-57457-1
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.04
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.01


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