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Case report: Multiorgan involvement with congenital zika syndrome

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dc.contributor.author Cachay Figueroa, Rodrigo Antonio
dc.contributor.author Schwalb Calderon, Alvaro
dc.contributor.author Watanabe, T.
dc.contributor.author Guzman, D.
dc.contributor.author Jaenisch, T.
dc.contributor.author Guillén-Pinto, D.
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.date.accessioned 2020-12-14T16:06:11Z
dc.date.available 2020-12-14T16:06:11Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8674
dc.description.abstract We report the case of an infant born with congenital Zika syndrome (CZS). During the largest Zika virus (ZIKV) outbreak in Peru, the mother presented with fever and rash that were confirmed to be due to ZIKV by real-time PCR. The infant was born with severe microcephaly. Imaging revealed corpus callosum dysgenesis, lissencephaly, ventriculomegaly, and calcifications. Mild hypertrophic cardiomyopathy with diastolic dysfunction was reported in the echocardiogram. Valgus deviation of the lower extremities and a left clubfoot were diagnosed at birth. The hip ultrasound showed incipient signs of Graf type II dysplasia. The findings confirm that CZS is a multiorgan phenotype in which microcephaly is merely the tip of the iceberg. A multidisciplinary approach is needed for the evaluation of these children. Copyright © 2020 by The American Society of Tropical Medicine and Hygiene. en_US
dc.language.iso eng
dc.publisher American Society of Tropical Medicine and Hygiene
dc.relation.ispartof urn:issn:1476-1645
dc.relation.ispartofseries American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Case Report en_US
dc.subject Multiorgan Involvement en_US
dc.subject Congenital Zika Syndrome en_US
dc.title Case report: Multiorgan involvement with congenital zika syndrome en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.20-0421
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06

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