Case report: Multiorgan involvement with congenital zika syndrome

Guzman, D.; Schwalb Calderon, Alvaro; Gotuzzo Herencia, José Eduardo; Watanabe, T.; Cachay Figueroa, Rodrigo Antonio; Jaenisch, T.; Guillén Pinto, Daniel

dc.contributor.author	Cachay Figueroa, Rodrigo Antonio
dc.contributor.author	Schwalb Calderon, Alvaro
dc.contributor.author	Watanabe, T.
dc.contributor.author	Guzman, D.
dc.contributor.author	Jaenisch, T.
dc.contributor.author	Guillén Pinto, Daniel
dc.contributor.author	Gotuzzo Herencia, José Eduardo
dc.date.accessioned	2020-12-14T16:06:11Z
dc.date.available	2020-12-14T16:06:11Z
dc.date.issued	2020
dc.identifier.uri	https://hdl.handle.net/20.500.12866/8674
dc.description.abstract	We report the case of an infant born with congenital Zika syndrome (CZS). During the largest Zika virus (ZIKV) outbreak in Peru, the mother presented with fever and rash that were confirmed to be due to ZIKV by real-time PCR. The infant was born with severe microcephaly. Imaging revealed corpus callosum dysgenesis, lissencephaly, ventriculomegaly, and calcifications. Mild hypertrophic cardiomyopathy with diastolic dysfunction was reported in the echocardiogram. Valgus deviation of the lower extremities and a left clubfoot were diagnosed at birth. The hip ultrasound showed incipient signs of Graf type II dysplasia. The findings confirm that CZS is a multiorgan phenotype in which microcephaly is merely the tip of the iceberg. A multidisciplinary approach is needed for the evaluation of these children. Copyright © 2020 by The American Society of Tropical Medicine and Hygiene.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Case Report	en_US
dc.subject	Multiorgan Involvement	en_US
dc.subject	Congenital Zika Syndrome	en_US
dc.title	Case report: Multiorgan involvement with congenital zika syndrome	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.20-0421
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645