Comorbid depression in medical diseases

Bullinger, M.; Moss-Morris, R.; Mehnert, A.; Steptoe, A.; Miranda, J. Jaime; Köhler-Forsberg, O.; Whooley, M.A.; Gold, S.M.; Otte, C.

dc.contributor.author	Gold, S.M.
dc.contributor.author	Köhler-Forsberg, O.
dc.contributor.author	Moss-Morris, R.
dc.contributor.author	Mehnert, A.
dc.contributor.author	Miranda, J. Jaime
dc.contributor.author	Bullinger, M.
dc.contributor.author	Steptoe, A.
dc.contributor.author	Whooley, M.A.
dc.contributor.author	Otte, C.
dc.date.accessioned	2020-12-14T16:06:25Z
dc.date.available	2020-12-14T16:06:25Z
dc.date.issued	2020
dc.identifier.uri	https://hdl.handle.net/20.500.12866/8716
dc.description.abstract	Depression is one of the most common comorbidities of many chronic medical diseases including cancer and cardiovascular, metabolic, inflammatory and neurological disorders. Indeed, the prevalence of depression in these patient groups is often substantially higher than in the general population, and depression accounts for a substantial part of the psychosocial burden of these disorders. Many factors can contribute to the occurrence of comorbid depression, such as shared genetic factors, converging biological pathways, social factors, health behaviours and psychological factors. Diagnosis of depression in patients with a medical disorder can be particularly challenging owing to symptomatic overlap. Although pharmacological and psychological treatments can be effective, adjustments may need to be made for patients with a comorbid medical disorder. In addition, symptoms or treatments of medical disorders may interfere with the treatment of depression. Conversely, symptoms of depression may decrease adherence to treatment of both disorders. Thus, comprehensive treatment plans are necessary to optimize care.	en_US
dc.language.iso	eng
dc.publisher	Springer
dc.relation.ispartofseries	Nature Reviews. Disease Primers
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Neuroscience	en_US
dc.subject	Translational research	en_US
dc.title	Comorbid depression in medical diseases	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1038/s41572-020-0200-2
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.02.00
dc.relation.issn	2056-676X