Universidad Peruana Cayetano Heredia

Critical review of multimorbidity outcome measures suitable for low-income and middle-income country settings: Perspectives from the Global Alliance for Chronic Diseases (GACD) researchers

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dc.contributor.author Hurst, J.R.
dc.contributor.author Agarwal, G.
dc.contributor.author Van Boven, J.F.M.
dc.contributor.author Daivadanam, M.
dc.contributor.author Gould, G.S.
dc.contributor.author Wan-Chun Huang, E.
dc.contributor.author Maulik, P.K.
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Owolabi, M.O.
dc.contributor.author Premji, S.S.
dc.contributor.author Soriano, J.B.
dc.contributor.author Vedanthan, R.
dc.contributor.author Yan, L.
dc.contributor.author Levitt, N.
dc.date.accessioned 2020-12-14T16:06:26Z
dc.date.available 2020-12-14T16:06:26Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8721
dc.description.abstract Objectives: There is growing recognition around the importance of multimorbidity in low-income and middle-income country (LMIC) settings, and specifically the need for pragmatic intervention studies to reduce the risk of developing multimorbidity, and of mitigating the complications and progression of multimorbidity in LMICs. One of many challenges in completing such research has been the selection of appropriate outcomes measures. A 2018 Delphi exercise to develop a core-outcome set for multimorbidity research did not specifically address the challenges of multimorbidity in LMICs where the global burden is greatest, patterns of disease often differ and health systems are frequently fragmented. We, therefore, aimed to summarise and critically review outcome measures suitable for studies investigating mitigation of multimorbidity in LMIC settings. Setting LMIC. Participants People with multimorbidity. Outcome measures Identification of all outcome measures. Results We present a critical review of outcome measures across eight domains: mortality, quality of life, function, health economics, healthcare access and utilisation, treatment burden, measures of â € Healthy Living' and self-efficacy and social functioning. Conclusions Studies in multimorbidity are necessarily diverse and thus different outcome measures will be appropriate for different study designs. Presenting the diversity of outcome measures across domains should provide a useful summary for researchers, encourage the use of multiple domains in multimorbidity research, and provoke debate and progress in the field. en_US
dc.language.iso eng
dc.publisher BMJ Publishing Group
dc.relation.ispartofseries BMJ Open
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Review en_US
dc.subject multimorbidity en_US
dc.subject low-income country en_US
dc.subject middle-income country en_US
dc.subject Global Alliance for Chronic Diseases en_US
dc.title Critical review of multimorbidity outcome measures suitable for low-income and middle-income country settings: Perspectives from the Global Alliance for Chronic Diseases (GACD) researchers en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1136/bmjopen-2020-037079
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00
dc.relation.issn 2044-6055


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