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Population Screening for Urine Antigens to Detect Asymptomatic Subarachnoid Neurocysticercosis: A Pilot Study in Northern Peru

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dc.contributor.author McCleery, E.
dc.contributor.author Allen, S.E.
dc.contributor.author Moyano, L.M.
dc.contributor.author Gamboa, R.
dc.contributor.author Vilchez, P.
dc.contributor.author Muro, C.
dc.contributor.author Castillo, Y.
dc.contributor.author Dorny, P.
dc.contributor.author Garcia, H.H.
dc.contributor.author O’Neal, S.E.
dc.date.accessioned 2020-12-14T16:06:33Z
dc.date.available 2020-12-14T16:06:33Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8737
dc.description.abstract Subarachnoid neurocysticercosis (SANCC) is a severe and progressive brain infection with Taenia solium. We performed a pilot study of noninvasive screening for SANCC in two endemic villages in northern Peru using a urine antigen screen followed by brain magnetic resonance imaging for participants with elevated levels of antigen. Among the 978 participants screened, we identified eight individuals with SANCC, many of whom were asymptomatic. This represents a minimum prevalence of 0.8% of SANCC, a level higher than expected based on prior studies, and a positive predictive value of 62% for our novel urine screening test. Future studies should confirm whether early detection and management improve clinical outcomes. en_US
dc.language.iso eng
dc.publisher American Society of Tropical Medicine and Hygiene
dc.relation.ispartof urn:issn:1476-1645
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject UNAVAILABLE en_US
dc.title Population Screening for Urine Antigens to Detect Asymptomatic Subarachnoid Neurocysticercosis: A Pilot Study in Northern Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.20-0196
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06 es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06


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