Diagnosis of plasmodium vivax by loop-mediated isothermal amplification in febrile patient samples from loreto, Perú

Torres Fajardo, Katherine Jessica; Infante, B.; Ding, X.C.; Incardona, S.; Nolasco, O.; Contreras-Mancilla, J.; Gamboa Vilela, Dionicia Baziliza

dc.contributor.author	Nolasco, O.
dc.contributor.author	Infante, B.
dc.contributor.author	Contreras-Mancilla, J.
dc.contributor.author	Incardona, S.
dc.contributor.author	Ding, X.C.
dc.contributor.author	Gamboa Vilela, Dionicia Baziliza
dc.contributor.author	Torres Fajardo, Katherine Jessica
dc.date.accessioned	2020-12-14T16:10:01Z
dc.date.available	2020-12-14T16:10:01Z
dc.date.issued	2020
dc.identifier.uri	https://hdl.handle.net/20.500.12866/8748
dc.description.abstract	Plasmodium vivax is co-endemic with Plasmodium falciparum in Peru, and optimum management requires distinguishing these two species in the blood of patients. For the differential identification of P. vivax and other Plasmodium spp., the LoopampTM Malaria Pan Detection Kit in combination with the Loopamp Malaria Pv Detection Kit (Eiken Chemical Co. Ltd., Tokyo, Japan) was used to evaluate 559 whole blood samples collected in 2017 from febrile patients with suspected malaria attending different health facilities in the Loreto region. The Loopamp Malaria Pan Detection Kit showed a sensitivity of 87.7% (95% CI: 83.5-91.9) and a specificity of 94.4% (95% CI: 91.9-96.9) and good agreement with PCR (Cohen's kappa 0.8266, 95% CI: 0.7792-0.874). By comparison, the Loopamp Malaria Pv Detection Kit showed a similar sensitivity (84.4%, 95% CI: 79.0-89.7) and specificity (92.4%, 95% CI: 89.7-95.0) and substantial agreement with PCR (Cohen's kappa: 0.7661, 95% CI: 0.7088-0.8234).	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Plasmodium vivax	en_US
dc.subject	Isothermal Amplification	en_US
dc.subject	Febrile Patient Samples	en_US
dc.subject	Loreto	en_US
dc.subject	Perú	en_US
dc.title	Diagnosis of plasmodium vivax by loop-mediated isothermal amplification in febrile patient samples from loreto, Perú	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.20-0212
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645