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Diagnosis of plasmodium vivax by loop-mediated isothermal amplification in febrile patient samples from loreto, Perú

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dc.contributor.author Nolasco, O.
dc.contributor.author Infante, B.
dc.contributor.author Contreras-Mancilla, J.
dc.contributor.author Incardona, S.
dc.contributor.author Ding, X.C.
dc.contributor.author Gamboa Vilela, Dionicia Baziliza
dc.contributor.author Torres Fajardo, Katherine Jessica
dc.date.accessioned 2020-12-14T16:10:01Z
dc.date.available 2020-12-14T16:10:01Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8748
dc.description.abstract Plasmodium vivax is co-endemic with Plasmodium falciparum in Peru, and optimum management requires distinguishing these two species in the blood of patients. For the differential identification of P. vivax and other Plasmodium spp., the LoopampTM Malaria Pan Detection Kit in combination with the Loopamp Malaria Pv Detection Kit (Eiken Chemical Co. Ltd., Tokyo, Japan) was used to evaluate 559 whole blood samples collected in 2017 from febrile patients with suspected malaria attending different health facilities in the Loreto region. The Loopamp Malaria Pan Detection Kit showed a sensitivity of 87.7% (95% CI: 83.5-91.9) and a specificity of 94.4% (95% CI: 91.9-96.9) and good agreement with PCR (Cohen's kappa 0.8266, 95% CI: 0.7792-0.874). By comparison, the Loopamp Malaria Pv Detection Kit showed a similar sensitivity (84.4%, 95% CI: 79.0-89.7) and specificity (92.4%, 95% CI: 89.7-95.0) and substantial agreement with PCR (Cohen's kappa: 0.7661, 95% CI: 0.7088-0.8234). en_US
dc.language.iso eng
dc.publisher American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Plasmodium vivax en_US
dc.subject Isothermal Amplification en_US
dc.subject Febrile Patient Samples en_US
dc.subject Loreto en_US
dc.subject Perú en_US
dc.title Diagnosis of plasmodium vivax by loop-mediated isothermal amplification in febrile patient samples from loreto, Perú en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.20-0212
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn 1476-1645


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