DSpace Repository

Odontogenic Carcinosarcoma: Clinicopathologic Features of 2 Cases

Show simple item record

dc.contributor.author Soares, C.D.
dc.contributor.author Delgado-Azañero, W.
dc.contributor.author Morais, T.M.D.L.
dc.contributor.author de Almeida, O.P.
dc.contributor.author Ghersi Miranda, H.
dc.date.accessioned 2020-12-14T16:10:14Z
dc.date.available 2020-12-14T16:10:14Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8812
dc.description.abstract This study reports 2 odontogenic carcinosarcomas, including the clinicopathologic and immunoprofile characteristics of these rare tumors. The first case occurred in a 22-year-old male presenting a bilobular mass involving the gingiva and bone of the premolar region of the left mandible, with paresthesia of the lower lip. Microscopic examination revealed a tumor similar to ameloblastic fibrosarcoma, with atypical mesenchymal cells; however, the odontogenic epithelium also showed atypia. In the second case, a 16-year-old female had a painless, asymptomatic, large intraosseous mandibular lesion. The patient received radiotherapy to treat a rhabdomyosarcoma of the parotid 13 years before. The tumor was composed of atypical spindle cells, positive for vimentin and smooth muscle actin, intermingled with malignant odontogenic epithelium. Both epithelial and mesenchymal components of the tumors showed high index of p53- and Ki67-positive cells. The first case was diagnosed as odontogenic carcinosarcoma possibly originated from an ameloblastic fibrosarcoma, and the second as de novo odontogenic carcinosarcoma possibly caused by previous radiotherapy. en_US
dc.language.iso eng
dc.publisher SAGE Publications
dc.relation.ispartofseries International Journal of Surgical Pathology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Odontogenic Carcinosarcoma en_US
dc.subject Clinicopathologic en_US
dc.title Odontogenic Carcinosarcoma: Clinicopathologic Features of 2 Cases en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1177/1066896919888578
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.09
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.11
dc.relation.issn 1940-2465


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/restrictedAccess Except where otherwise noted, this item's license is described as info:eu-repo/semantics/restrictedAccess

Search DSpace


Browse

My Account

Statistics