Universidad Peruana Cayetano Heredia

Repositioning of the global epicentre of non-optimal cholesterol

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dc.contributor.author Taddei, C.
dc.contributor.author Zhou, B.
dc.contributor.author Bixby, H.
dc.contributor.author Carrillo Larco, Rodrigo Martín
dc.contributor.author Danaei, G.
dc.contributor.author Jackson, R.T.
dc.contributor.author Farzadfar, F.
dc.contributor.author Sophiea, M.K.
dc.contributor.author Di Cesare, M.
dc.contributor.author Iurilli, M.L.C.
dc.contributor.author Martinez, A.R.
dc.contributor.author Asghari, G.
dc.contributor.author Dhana, K.
dc.contributor.author Gulayin, P.
dc.contributor.author Kakarmath, S.
dc.contributor.author Santero, M.
dc.contributor.author Voortman, T.
dc.contributor.author Riley, L.M.
dc.contributor.author Cowan, M.J.
dc.contributor.author Savin, S.
dc.contributor.author Bennett, J.E.
dc.contributor.author Stevens, G.A.
dc.contributor.author Paciorek, C.J.
dc.contributor.author Aekplakorn, W.
dc.contributor.author Cifkova, R.
dc.contributor.author Giampaoli, S.
dc.contributor.author Kengne, A.P.
dc.contributor.author Khang, Y.-H.
dc.contributor.author Kuulasmaa, K.
dc.contributor.author Laxmaiah, A.
dc.contributor.author Margozzini, P.
dc.contributor.author Mathur, P.
dc.contributor.author Nordestgaard, B.G.
dc.contributor.author Zhao, D.
dc.contributor.author Aadahl, M.
dc.contributor.author Abarca-Gómez, L.
dc.contributor.author Rahim, H.A.
dc.contributor.author Abu-Rmeileh, N.M.
dc.contributor.author Acosta-Cazares, B.
dc.contributor.author Adams, R.J.
dc.contributor.author Agdeppa, I.A.
dc.contributor.author Aghazadeh-Attari, J.
dc.contributor.author Aguilar-Salinas, C.A.
dc.contributor.author Agyemang, C.
dc.contributor.author Ahluwalia, T.S.
dc.contributor.author Ahmad, N.A.
dc.contributor.author Ahmadi, A.
dc.contributor.author Ahmadi, N.
dc.contributor.author Ahmed, S.H.
dc.contributor.author Ahrens, W.
dc.contributor.author Ajlouni, K.
dc.contributor.author Alarouj, M.
dc.contributor.author AlBuhairan, F.
dc.contributor.author AlDhukair, S.
dc.contributor.author Ali, M.M.
dc.contributor.author Alkandari, A.
dc.contributor.author Alkerwi, A.
dc.contributor.author Aly, E.
dc.contributor.author Amarapurkar, D.N.
dc.contributor.author Amouyel, P.
dc.contributor.author Andersen, L.B.
dc.contributor.author Anderssen, S.A.
dc.contributor.author Anjana, R.M.
dc.contributor.author Ansari-Moghaddam, A.
dc.contributor.author Aounallah-Skhiri, H.
dc.contributor.author Araújo, J.
dc.contributor.author Ariansen, I.
dc.contributor.author Aris, T.
dc.contributor.author Arku, R.E.
dc.contributor.author Arlappa, N.
dc.contributor.author Aryal, K.K.
dc.contributor.author Aspelund, T.
dc.contributor.author Assunção, M.C.F.
dc.contributor.author Auvinen, J.
dc.contributor.author Avdicová, M.
dc.contributor.author Azevedo, A.
dc.contributor.author Azizi, F.
dc.contributor.author Azmin, M.
dc.contributor.author Balakrishna, N.
dc.contributor.author Bamoshmoosh, M.
dc.contributor.author Banach, M.
dc.contributor.author Bandosz, P.
dc.contributor.author Banegas, J.R.
dc.contributor.author Barbagallo, C.M.
dc.contributor.author Barceló, A.
dc.contributor.author Barkat, A.
dc.contributor.author Bata, I.
dc.contributor.author Batieha, A.M.
dc.contributor.author Batyrbek, A.
dc.contributor.author Baur, L.A.
dc.contributor.author Beaglehole, R.
dc.contributor.author Belavendra, A.
dc.contributor.author Ben Romdhane, H.
dc.contributor.author Benet, M.
dc.contributor.author Benn, M.
dc.contributor.author Berkinbayev, S.
dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Bernotiene, G.
dc.contributor.author Bettiol, H.
dc.contributor.author Bhargava, S.K.
dc.contributor.author Bi, Y.
dc.contributor.author Bienek, A.
dc.contributor.author Bikbov, M.
dc.contributor.author Bista, B.
dc.contributor.author Bjerregaard, P.
dc.contributor.author Bjertness, E.
dc.contributor.author Bjertness, M.B.
dc.contributor.author Björkelund, C.
dc.contributor.author Bloch, K.V.
dc.contributor.author Blokstra, A.
dc.contributor.author Bo, S.
dc.contributor.author Boehm, B.O.
dc.contributor.author Boggia, J.G.
dc.contributor.author Boissonnet, C.P.
dc.contributor.author Bonaccio, M.
dc.contributor.author Bongard, V.
dc.contributor.author Borchini, R.
dc.contributor.author Borghs, H.
dc.contributor.author Bovet, P.
dc.contributor.author Brajkovich, I.
dc.contributor.author Breckenkamp, J.
dc.contributor.author Brenner, H.
dc.contributor.author Brewster, L.M.
dc.contributor.author Bruno, G.
dc.contributor.author Bugge, A.
dc.contributor.author Busch, M.A.
dc.contributor.author de León, A.C.
dc.contributor.author Cacciottolo, J.
dc.contributor.author Can, G.
dc.contributor.author Cândido, A.P.C.
dc.contributor.author Capanzana, M.V.
dc.contributor.author Capuano, E.
dc.contributor.author Capuano, V.
dc.contributor.author Cardoso, V.C.
dc.contributor.author Carvalho, J.
dc.contributor.author Casanueva, F.F.
dc.contributor.author Censi, L.
dc.contributor.author Chadjigeorgiou, C.A.
dc.contributor.author Chamukuttan, S.
dc.contributor.author Chaturvedi, N.
dc.contributor.author Chen, C.-J.
dc.contributor.author Chen, F.
dc.contributor.author Chen, S.
dc.contributor.author Cheng, C.-Y.
dc.contributor.author Cheraghian, B.
dc.contributor.author Chetrit, A.
dc.contributor.author Chiou, S.-T.
dc.contributor.author Chirlaque, M.-D.
dc.contributor.author Cho, B.
dc.contributor.author Cho, Y.
dc.contributor.author Chudek, J.
dc.contributor.author Claessens, F.
dc.contributor.author Clarke, J.
dc.contributor.author Clays, E.
dc.contributor.author Concin, H.
dc.contributor.author Confortin, S.C.
dc.contributor.author Cooper, C.
dc.contributor.author Costanzo, S.
dc.contributor.author Cottel, D.
dc.contributor.author Cowell, C.
dc.contributor.author Crujeiras, A.B.
dc.contributor.author Csilla, S.
dc.contributor.author Cui, L.
dc.contributor.author Cureau, F.V.
dc.contributor.author D’Arrigo, G.
dc.contributor.author d’Orsi, E.
dc.contributor.author Dallongeville, J.
dc.contributor.author Damasceno, A.
dc.contributor.author Dankner, R.
dc.contributor.author Dantoft, T.M.
dc.contributor.author Dauchet, L.
dc.contributor.author Davletov, K.
dc.contributor.author De Backer, G.
dc.contributor.author De Bacquer, D.
dc.contributor.author de Gaetano, G.
dc.contributor.author De Henauw, S.
dc.contributor.author de Oliveira, P.D.
dc.contributor.author De Ridder, D.
dc.contributor.author De Smedt, D.
dc.contributor.author Deepa, M.
dc.contributor.author Deev, A.D.
dc.contributor.author Dehghan, A.
dc.contributor.author Delisle, H.
dc.contributor.author Dennison, E.
dc.contributor.author Deschamps, V.
dc.contributor.author Dhimal, M.
dc.contributor.author Di Castelnuovo, A.F.
dc.contributor.author Dika, Z.
dc.contributor.author Djalalinia, S.
dc.contributor.author Dobson, A.J.
dc.contributor.author Donfrancesco, C.
dc.contributor.author Donoso, S.P.
dc.contributor.author Döring, A.
dc.contributor.author Dorobantu, M.
dc.contributor.author Dragano, N.
dc.contributor.author Drygas, W.
dc.contributor.author Du, Y.
dc.contributor.author Duante, C.A.
dc.contributor.author Duda, R.B.
dc.contributor.author Dzerve, V.
dc.contributor.author Dziankowska-Zaborszczyk, E.
dc.contributor.author Eddie, R.
dc.contributor.author Eftekhar, E.
dc.contributor.author Eggertsen, R.
dc.contributor.author Eghtesad, S.
dc.contributor.author Eiben, G.
dc.contributor.author Ekelund, U.
dc.contributor.author El Ati, J.
dc.contributor.author Eldemire-Shearer, D.
dc.contributor.author Eliasen, M.
dc.contributor.author Elosua, R.
dc.contributor.author Erasmus, R.T.
dc.contributor.author Erbel, R.
dc.contributor.author Erem, C.
dc.contributor.author Eriksen, L.
dc.contributor.author Eriksson, J.G.
dc.contributor.author Escobedo-de la Peña, J.
dc.contributor.author Eslami, S.
dc.contributor.author Esmaeili, A.
dc.contributor.author Evans, Alun
dc.contributor.author Faeh, D.
dc.contributor.author Fall, C.H.
dc.contributor.author Faramarzi, E.
dc.contributor.author Farjam, M.
dc.contributor.author Fattahi, M.R.
dc.contributor.author Felix-Redondo, F.J.
dc.contributor.author Ferguson, T.S.
dc.contributor.author Fernández-Bergés, D.
dc.contributor.author Ferrante, D.
dc.contributor.author Ferrari, M.
dc.contributor.author Ferreccio, C.
dc.contributor.author Ferrieres, J.
dc.contributor.author Föger, B.
dc.contributor.author Foo, L.H.
dc.contributor.author Forslund, A.-S.
dc.contributor.author Forsner, M.
dc.contributor.author Fouad, H.M.
dc.contributor.author Francis, D.K.
dc.contributor.author do Carmo Franco, M.
dc.contributor.author Franco, O.H.
dc.contributor.author Frontera, G.
dc.contributor.author Fujita, Y.
dc.contributor.author Fumihiko, M.
dc.contributor.author Furusawa, T.
dc.contributor.author Gaciong, Z.
dc.contributor.author Galvano, F.
dc.contributor.author Gao, J.
dc.contributor.author Garcia-de-la-Hera, M.
dc.contributor.author Garnett, S.P.
dc.contributor.author Gaspoz, J.-M.
dc.contributor.author Gasull, M.
dc.contributor.author Gazzinelli, A.
dc.contributor.author Geleijnse, J.M.
dc.contributor.author Ghanbari, A.
dc.contributor.author Ghasemi, E.
dc.contributor.author Gheorghe-Fronea, O.-F.
dc.contributor.author Ghimire, A.
dc.contributor.author Gianfagna, F.
dc.contributor.author Gill, T.K.
dc.contributor.author Giovannelli, J.
dc.contributor.author Gironella, G.
dc.contributor.author Giwercman, A.
dc.contributor.author Goltzman, D.
dc.contributor.author Gonçalves, H.
dc.contributor.author Gonzalez-Chica, D.A.
dc.contributor.author Gonzalez-Gross, M.
dc.contributor.author González-Rivas, J.P.
dc.contributor.author González-Villalpando, C.
dc.contributor.author González-Villalpando, M.-E.
dc.contributor.author Gonzalez, Angel R.
dc.contributor.author Gottrand, F.
dc.contributor.author Graff-Iversen, S.
dc.contributor.author Grafnetter, D.
dc.contributor.author Gregor, R.D.
dc.contributor.author Grodzicki, T.
dc.contributor.author Grøntved, A.
dc.contributor.author Grosso, G.
dc.contributor.author Gruden, G.
dc.contributor.author Gu, D.
dc.contributor.author Guallar-Castillón, P.
dc.contributor.author Guan, O.P.
dc.contributor.author Gudmundsson, E.F.
dc.contributor.author Gudnason, V.
dc.contributor.author Guerrero, R.
dc.contributor.author Guessous, I.
dc.contributor.author Gunnlaugsdottir, J.
dc.contributor.author Gupta, R.
dc.contributor.author Gutierrez, L.
dc.contributor.author Gutzwiller, F.
dc.contributor.author Ha, S.
dc.contributor.author Hadaegh, F.
dc.contributor.author Haghshenas, R.
dc.contributor.author Hakimi, H.
dc.contributor.author Hambleton, I.R.
dc.contributor.author Hamzeh, B.
dc.contributor.author Hantunen, S.
dc.contributor.author Kumar, R.H.
dc.contributor.author Hashemi-Shahri, S.M.
dc.contributor.author Hata, J.
dc.contributor.author Haugsgjerd, T.
dc.contributor.author Hayes, A.J.
dc.contributor.author He, J.
dc.contributor.author He, Y.
dc.contributor.author Hendriks, M.E.
dc.contributor.author Henriques, A.
dc.contributor.author Herrala, S.
dc.contributor.author Heshmat, R.
dc.contributor.author Hill, A.G.
dc.contributor.author Ho, S.Y.
dc.contributor.author Ho, S.C.
dc.contributor.author Hobbs, M.
dc.contributor.author Hofman, A.
dc.contributor.author Homayounfar, R.
dc.contributor.author Hopman, W.M.
dc.contributor.author Horimoto, A.R.V.R.
dc.contributor.author Hormiga, C.M.
dc.contributor.author Horta, B.L.
dc.contributor.author Houti, L.
dc.contributor.author Howitt, C.
dc.contributor.author Htay, T.T.
dc.contributor.author Htet, A.S.
dc.contributor.author Htike, M.M.T.
dc.contributor.author Huerta, J.M.
dc.contributor.author Huhtaniemi, I.T.
dc.contributor.author Huisman, M.
dc.contributor.author Hunsberger, M.L.
dc.contributor.author Husseini, A.S.
dc.contributor.author Huybrechts, I.
dc.contributor.author Hwalla, N.
dc.contributor.author Iacoviello, L.
dc.contributor.author Iannone, A.G.
dc.contributor.author Ibrahim, M.M.
dc.contributor.author Wong, N.I.
dc.contributor.author Iglesia, I.
dc.contributor.author Ikeda, N.
dc.contributor.author Ikram, M.A.
dc.contributor.author Iotova, V.
dc.contributor.author Irazola, V.E.
dc.contributor.author Ishida, T.
dc.contributor.author Islam, M.
dc.contributor.author al-Safi Ismail, A.
dc.contributor.author Iwasaki, M.
dc.contributor.author Jacobs, J.M.
dc.contributor.author Jaddou, H.Y.
dc.contributor.author Jafar, T.
dc.contributor.author James, K.
dc.contributor.author Jamrozik, K.
dc.contributor.author Janszky, I.
dc.contributor.author Janus, E.
dc.contributor.author Jarvelin, M.-R.
dc.contributor.author Jasienska, G.
dc.contributor.author Jelakovic, A.
dc.contributor.author Jelakovic, B.
dc.contributor.author Jennings, G.
dc.contributor.author Jensen, G.B.
dc.contributor.author Jeong, S.-L.
dc.contributor.author Jha, A.K.
dc.contributor.author Jiang, C.Q.
dc.contributor.author Jimenez, R.O.
dc.contributor.author Jöckel, K.-H.
dc.contributor.author Joffres, M.
dc.contributor.author Jokelainen, J.J.
dc.contributor.author Jonas, J.B.
dc.contributor.author Jørgensen, T.
dc.contributor.author Joshi, P.
dc.contributor.author Joukar, F.
dc.contributor.author Józwiak, J.
dc.contributor.author Juolevi, A.
dc.contributor.author Kafatos, A.
dc.contributor.author Kajantie, E.O.
dc.contributor.author Kalter-Leibovici, O.
dc.contributor.author Kamaruddin, N.A.
dc.contributor.author Kamstrup, P.R.
dc.contributor.author Karki, K.B.
dc.contributor.author Katz, J.
dc.contributor.author Kauhanen, J.
dc.contributor.author Kaur, P.
dc.contributor.author Kavousi, M.
dc.contributor.author Kazakbaeva, G.
dc.contributor.author Keil, U.
dc.contributor.author Keinänen-Kiukaanniemi, S.
dc.contributor.author Kelishadi, R.
dc.contributor.author Keramati, M.
dc.contributor.author Kerimkulova, A.
dc.contributor.author Kersting, M.
dc.contributor.author Khader, Y.S.
dc.contributor.author Khalili, D.
dc.contributor.author Khateeb, M.
dc.contributor.author Kheradmand, M.
dc.contributor.author Khosravi, A.
dc.contributor.author Kiechl-Kohlendorfer, U.
dc.contributor.author Kiechl, S.
dc.contributor.author Killewo, J.
dc.contributor.author Kim, H.C.
dc.contributor.author Kim, J.
dc.contributor.author Kim, Y.-Y.
dc.contributor.author Klumbiene, J.
dc.contributor.author Knoflach, M.
dc.contributor.author Ko, S.
dc.contributor.author Kohler, H.-P.
dc.contributor.author Kohler, I.V.
dc.contributor.author Kolle, E.
dc.contributor.author Kolsteren, P.
dc.contributor.author König, J.
dc.contributor.author Korpelainen, R.
dc.contributor.author Korrovits, P.
dc.contributor.author Kos, J.
dc.contributor.author Koskinen, S.
dc.contributor.author Kouda, K.
dc.contributor.author Kowlessur, S.
dc.contributor.author Kratzer, W.
dc.contributor.author Kriemler, S.
dc.contributor.author Kristensen, P.L.
dc.contributor.author Krokstad, S.
dc.contributor.author Kromhout, D.
dc.contributor.author Kujala, U.M.
dc.contributor.author Kurjata, P.
dc.contributor.author Kyobutungi, C.
dc.contributor.author Laamiri, F.Z.
dc.contributor.author Laatikainen, T.
dc.contributor.author Lachat, C.
dc.contributor.author Laid, Y.
dc.contributor.author Lam, T.H.
dc.contributor.author Lambrinou, C.-P.
dc.contributor.author Lanska, V.
dc.contributor.author Lappas, G.
dc.contributor.author Larijani, B.
dc.contributor.author Latt, T.S.
dc.contributor.author Laugsand, L.E.
dc.contributor.author Lazo Porras, María de los Ángeles
dc.contributor.author Lee, J.
dc.contributor.author Lee, J.
dc.contributor.author Lehmann, N.
dc.contributor.author Lehtimäki, T.
dc.contributor.author Levitt, N.S.
dc.contributor.author Li, Y.
dc.contributor.author Lilly, C.L.
dc.contributor.author Lim, W.-Y.
dc.contributor.author Lima-Costa, M.F.
dc.contributor.author Lin, H.-H.
dc.contributor.author Lin, X.
dc.contributor.author Lin, Y.-T.
dc.contributor.author Lind, L.
dc.contributor.author Linneberg, A.
dc.contributor.author Lissner, L.
dc.contributor.author Liu, J.
dc.contributor.author Loit, H.-M.
dc.contributor.author Lopez-Garcia, E.
dc.contributor.author Lopez, T.
dc.contributor.author Lotufo, P.A.
dc.contributor.author Lozano, J.E.
dc.contributor.author Luksiene, D.
dc.contributor.author Lundqvist, A.
dc.contributor.author Lundqvist, R.
dc.contributor.author Lunet, N.
dc.contributor.author Ma, G.
dc.contributor.author Machado-Coelho, G.L.L.
dc.contributor.author Machado-Rodrigues, A.M.
dc.contributor.author Machi, S.
dc.contributor.author Madar, A.A.
dc.contributor.author Maggi, S.
dc.contributor.author Magliano, D.J.
dc.contributor.author Magriplis, E.
dc.contributor.author Mahasampath, G.
dc.contributor.author Maire, B.
dc.contributor.author Makdisse, M.
dc.contributor.author Malekzadeh, F.
dc.contributor.author Malekzadeh, R.
dc.contributor.author Rao, K.M.
dc.contributor.author Manios, Y.
dc.contributor.author Mann, J.I.
dc.contributor.author Mansour-Ghanaei, F.
dc.contributor.author Manzato, E.
dc.contributor.author Marques-Vidal, P.
dc.contributor.author Martorell, R.
dc.contributor.author Mascarenhas, L.P.
dc.contributor.author Mathiesen, E.B.
dc.contributor.author Matsha, T.E.
dc.contributor.author Mavrogianni, C.
dc.contributor.author McFarlane, S.R.
dc.contributor.author McGarvey, S.T.
dc.contributor.author McLachlan, S.
dc.contributor.author McLean, R.M.
dc.contributor.author McLean, S.B.
dc.contributor.author McNulty, B.A.
dc.contributor.author Mediene-Benchekor, S.
dc.contributor.author Mehdipour, P.
dc.contributor.author Mehlig, K.
dc.contributor.author Mehrparvar, A.H.
dc.contributor.author Meirhaeghe, A.
dc.contributor.author Meisinger, C.
dc.contributor.author Menezes, A.M.B.
dc.contributor.author Menon, G.R.
dc.contributor.author Merat, S.
dc.contributor.author Mereke, A.
dc.contributor.author Meshram, I.I.
dc.contributor.author Metcalf, P.
dc.contributor.author Meyer, H.E.
dc.contributor.author Mi, J.
dc.contributor.author Michels, N.
dc.contributor.author Miller, J.C.
dc.contributor.author Minderico, C.S.
dc.contributor.author Mini, G.K.
dc.contributor.author Miquel, J.F.
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Mirjalili, M.R.
dc.contributor.author Mirrakhimov, E.
dc.contributor.author Modesti, P.A.
dc.contributor.author Moghaddam, S.S.
dc.contributor.author Mohajer, B.
dc.contributor.author Mohamed, M.K.
dc.contributor.author Mohammad, K.
dc.contributor.author Mohammadi, Z.
dc.contributor.author Mohammadifard, N.
dc.contributor.author Mohammadpourhodki, R.
dc.contributor.author Mohan, V.
dc.contributor.author Mohanna, S.
dc.contributor.author Yusoff, M.F.M.
dc.contributor.author Mohebbi, I.
dc.contributor.author Mohebi, F.
dc.contributor.author Moitry, M.
dc.contributor.author Møllehave, L.T.
dc.contributor.author Møller, N.C.
dc.contributor.author Molnár, D.
dc.contributor.author Momenan, A.
dc.contributor.author Mondo, C.K.
dc.contributor.author Monterrubio-Flores, E.
dc.contributor.author Moosazadeh, M.
dc.contributor.author Morejon, A.
dc.contributor.author Moreno, L.A.
dc.contributor.author Morgan, K.
dc.contributor.author Morin, S.N.
dc.contributor.author Moschonis, G.
dc.contributor.author Mossakowska, M.
dc.contributor.author Mostafa, A.
dc.contributor.author Mota, J.
dc.contributor.author Motlagh, M.E.
dc.contributor.author Motta, J.
dc.contributor.author Msyamboza, K.P.
dc.contributor.author Muiesan, M.L.
dc.contributor.author Müller-Nurasyid, M.
dc.contributor.author Mursu, J.
dc.contributor.author Mustafa, N.
dc.contributor.author Nabipour, I.
dc.contributor.author Naderimagham, S.
dc.contributor.author Nagel, G.
dc.contributor.author Naidu, B.M.
dc.contributor.author Najafi, F.
dc.contributor.author Nakamura, H.
dc.contributor.author Námešná, J.
dc.contributor.author Nang, E.E.K.
dc.contributor.author Nangia, V.B.
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dc.date.accessioned 2020-12-14T16:10:16Z
dc.date.available 2020-12-14T16:10:16Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8818
dc.description.abstract High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiovascular risk—changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million–4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world. en_US
dc.language.iso eng
dc.publisher Springer Nature
dc.relation.ispartofseries Nature
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Cardiovascular diseases en_US
dc.subject Risk factors en_US
dc.title Repositioning of the global epicentre of non-optimal cholesterol en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1038/s41586-020-2338-1
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.04
dc.relation.issn 1476-4687


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