Universidad Peruana Cayetano Heredia

Association between maternal exposure to particulate matter (PM2.5) and adverse pregnancy outcomes in Lima, Peru

Mostrar el registro sencillo del ítem

dc.contributor.author Tapia Aguirre, Vilma Lucrecia
dc.contributor.author Vasquez Apéstegui, Bertha Vanessa
dc.contributor.author Vu, B.
dc.contributor.author Liu, Y.
dc.contributor.author Steenland, K.
dc.contributor.author Gonzales Rengifo, Gustavo Francisco
dc.date.accessioned 2020-12-14T16:10:17Z
dc.date.available 2020-12-14T16:10:17Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8820
dc.description.abstract The literature shows associations between maternal exposures to PM2.5 and adverse pregnancy outcomes. There are few data from Latin America. We have examined PM2.5 and pregnancy outcomes in Lima. The study included 123,034 births from 2012 to 2016, at three public hospitals. We used estimated daily PM2.5 from a newly created model developed using ground measurements, satellite data, and a chemical transport model. Exposure was assigned based on district of residence (n = 39). Linear and logistic regression analyzes were used to estimate the associations between air pollution exposure and pregnancy outcomes. Increased exposure to PM2.5 during the entire pregnancy and in the first trimester was inversely associated with birth weight. We found a decrease of 8.13 g (−14.0; −1.84) overall and 18.6 g (−24.4, −12.8) in the first trimester, for an interquartile range (IQR) increase (9.2 µg/m3) in PM2.5. PM2.5 exposure was positively associated with low birth weight at term (TLBW) during entire pregnancy (OR: 1.11; 95% CI: 1.03–1.20), and at the first (OR: 1.11; 95% CI: 1.03–1.20), second (OR: 1.09; 95% CI: 1.01–1.17), and third trimester (OR: 1.10; 95% CI: 1.02–1.18) per IQR (9.2 µg/m3) increase. Higher exposure to PM2.5 was also associated with increased risk of small for gestational age (SGA). There were no statistically significant associations between PM2.5 exposure and preterm births (PTB). Exposure to higher concentrations of PM2.5 in Lima may decrease birth weight and increase the frequency of TLBW and SGA. Our study was inconsistent with the literature in finding no associations with preterm birth. en_US
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartofseries Journal of Exposure Science and Environmental Epidemiology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Air pollution en_US
dc.subject Birth weight en_US
dc.subject PM2.5 en_US
dc.subject Low birth weight en_US
dc.subject Fetal growth restriction en_US
dc.subject Small for gestational age en_US
dc.subject Preterm births en_US
dc.title Association between maternal exposure to particulate matter (PM2.5) and adverse pregnancy outcomes in Lima, Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1038/s41370-020-0223-5
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.09
dc.relation.issn 1559-064X


Ficheros en el ítem

Ficheros Tamaño Formato Ver

No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

info:eu-repo/semantics/restrictedAccess Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/restrictedAccess

Buscar en el Repositorio


Listar

Panel de Control

Estadísticas