Universidad Peruana Cayetano Heredia

Changes in hemoglobin levels with age and altitude in preschool-aged children in Peru: the assessment of two individual-based national databases

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dc.contributor.author Gonzales Rengifo, Gustavo Francisco
dc.contributor.author Tapia Aguirre, Vilma Lucrecia
dc.contributor.author Vásquez-Velásquez, Cinthya
dc.date.accessioned 2021-04-13T20:50:58Z
dc.date.available 2021-04-13T20:50:58Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/9126
dc.description.abstract According to the World Health Organization, the cutoff hemoglobin (Hb) value for defining anemia is 11 g/dL in preschool-aged children, and Hb measurements should be corrected above an altitude of 1000 meters. This study sought to determine the altitude at which the Hb value increases compared with that at sea level, Hb changes with age and region in Peru, the prevalence of anemia according to three different models used to correct Hb for altitude, and the association of the Hb value with stunting. Two individual-based Peruvian national databases were analyzed. Hb increased from an altitude of 375 meters. Hb concentration was lower at younger ages and higher at older ages. The increase in Hb with increasing altitude was lower in southern Peru. Implementing the different models for Hb measurement correction resulted in a higher and lower prevalence of anemia at altitudes >2500 and <2500 m, respectively, using the CDC adjustment. In children aged 6-23 months, the rate of stunting was lower in those with an Hb level of 10-12 g/dL (including mild anemia). In conclusion, the adjustment of Hb values for altitude should be considered before 1000 m and reference ranges should be adjusted to smaller groups of children instead of the same reference range for children aged 6-59 months. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries Annals of the New York Academy of Sciences
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Article en_US
dc.subject comparative study en_US
dc.subject controlled study en_US
dc.subject female en_US
dc.subject human en_US
dc.subject major clinical study en_US
dc.subject male en_US
dc.subject disease association en_US
dc.subject erythrocytosis en_US
dc.subject Peru en_US
dc.subject sea level en_US
dc.subject cross-sectional study en_US
dc.subject prevalence en_US
dc.subject altitude en_US
dc.subject child en_US
dc.subject preschool child en_US
dc.subject drinking water en_US
dc.subject infant en_US
dc.subject school child en_US
dc.subject Peruvian en_US
dc.subject data base en_US
dc.subject age en_US
dc.subject altitude adjustment en_US
dc.subject anemia en_US
dc.subject anthropometric parameters en_US
dc.subject ascorbic acid en_US
dc.subject clinical assessment en_US
dc.subject concentration process en_US
dc.subject environmental health en_US
dc.subject folic acid en_US
dc.subject hemoglobin en_US
dc.subject hemoglobin blood level en_US
dc.subject iron en_US
dc.subject nutritional assessment en_US
dc.subject protein expression en_US
dc.subject retinol en_US
dc.subject stunting en_US
dc.subject zinc en_US
dc.title Changes in hemoglobin levels with age and altitude in preschool-aged children in Peru: the assessment of two individual-based national databases en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1111/nyas.14520
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.00
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.04
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#6.01.01
dc.relation.issn 1749-6632


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