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Effect of augmented reality books in salivary cortisol levels in hospitalized pediatric patients: A randomized cross-over trial

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dc.contributor.author Alarcón Yaquetto, Dulce Esperanza
dc.contributor.author Tincopa, Jean P.
dc.contributor.author Guillén Pinto, Daniel
dc.contributor.author Bailon, Nataly
dc.contributor.author Cárcamo Cavagnaro, César Paul Eugenio
dc.date.accessioned 2021-04-13T20:50:59Z
dc.date.available 2021-04-13T20:50:59Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/9127
dc.description.abstract OBJECTIVE: This study sought to assess the effect of reading augmented reality (AR) books on salivary cortisol levels in hospitalized pediatric patients compared to reading a standard children's book. METHODS: This was a randomized, two-period, cross-over trial in hospitalized children aged 7-11 years. AR books currently in the market were used as intervention. Complete block randomization was used to randomize the order of the intervention. Children allocated to the 'AR-first' group received the book, a tablet and were left to interact independently with the technology for an hour. After a 48 -h wash-out period, children received a standard book. 'Standard-book-first' group received only the standard book and after wash-out received the tablet and the AR book. Salivary cortisol and a validated visual analogue scale (VAS) for psychological stress were assessed at the beginning and at the end of each intervention. RESULTS: A total of 29 children were recruited in the study. One was lost during follow up. Cortisol levels decreased after the AR intervention (P = 0.019). Nevertheless, the decrease was not greater than the one associated to reading the standard book. VAS scores increased after the AR intervention (P < 0.001). DISCUSSION: There is evidence of order and sequence effects that might explain results. First assessment of AR-based interventions on stress. Results justify further research. CONCLUSIONS: There was no evidence that reading AR books diminished cortisol levels more than reading a standard book. AR-books improved VAS score for psychological stress compared to a standard book. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries International Journal of Medical Informatics
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Article en_US
dc.subject controlled study en_US
dc.subject female en_US
dc.subject Hospitalization en_US
dc.subject human en_US
dc.subject male en_US
dc.subject priority journal en_US
dc.subject randomized controlled trial en_US
dc.subject clinical article en_US
dc.subject acute appendicitis en_US
dc.subject child en_US
dc.subject art en_US
dc.subject augmented reality en_US
dc.subject Augmented reality en_US
dc.subject book en_US
dc.subject Children's books en_US
dc.subject Cortisol en_US
dc.subject Cross over en_US
dc.subject crossover procedure en_US
dc.subject emotional stress en_US
dc.subject enzyme linked immunosorbent assay en_US
dc.subject follow up en_US
dc.subject Follow up en_US
dc.subject fracture en_US
dc.subject good clinical practice en_US
dc.subject hospital admission en_US
dc.subject hospitalized child en_US
dc.subject hydrocortisone en_US
dc.subject limited mobility en_US
dc.subject mastoiditis en_US
dc.subject mental stress en_US
dc.subject pediatric patient en_US
dc.subject Pediatric patients en_US
dc.subject Pediatrics en_US
dc.subject peritonitis en_US
dc.subject Psychological stress en_US
dc.subject Random processes en_US
dc.subject saliva level en_US
dc.subject Salivary cortisols en_US
dc.subject school child en_US
dc.subject Stress en_US
dc.subject visual analog scale en_US
dc.subject Visual analogue scale en_US
dc.subject Wash out en_US
dc.title Effect of augmented reality books in salivary cortisol levels in hospitalized pediatric patients: A randomized cross-over trial en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.ijmedinf.2021.104404
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.02.03
dc.relation.issn 1872-8243


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