Dementia in Latin America: Paving the way toward a regional action plan
Parra, M.A.; Baez, S.; Sedeño, L.; Gonzalez Campo, C.; Santamaría-García, H.; Aprahamian, I.; Bertolucci, P.H.F.; Bustin, J.; Camargos Bicalho, M.A.; Cano Gutierrez, C.; Caramelli, P.; Chaves, M.L.F.; Cogram, P.; Beber, B.C.; Court, F.A.; de Souza, L.C.; Custodio, N.; Damian, A.; de la Cruz, M.; Diehl Rodriguez, R.; Dozzi Brucki, S.M.; Fajersztajn, L.; Farías, G.A.; De Felice, F.G.; Ferrari, R.; de Oliveira, F.F.; Ferreira, S.T.; Ferretti, C.; Figueredo Balthazar, M.L.; Ferreira Frota, N.A.; Fuentes, P.; García, A.M.; Garcia Funegra, Patricia Jannet; de Gobbi Porto, F.H.; Duque Peñailillo, L.; Engler, H.W.; Maier, I.; Mata, I.F.; Gonzalez Billault, C.; Lopez, O.L.; Morelli, L.; Nitrini, R.; Quiroz, Y.T.; Guerrero Barragan, A.; Huepe, D.; Pio, F.J.; Suemoto, C.K.; Kochhann, R.; Kochen, S.; Kumfor, F.; Lanata, S.; Miller, B.; Mansur, L.L.; Hosogi, M.L.; Lillo, P.; Llibre Guerra, J.; Lira, D.; Lopera, F.; Comas, A.; Avila-Funes, J.A.; Sosa, A.L.; Ramos, C.; De Paula França Resende, E.; Snyder, H.M.; Tarnanas, I.; Yokoyama, J.; Llibre, J.; Cardona, J.F.; Possin, K.; Kosik, K.S.; Montesinos, R.; Moguilner, S.; Solis, P.C.L.; De Lucena Ferretti Rebustini, R.E..; Ramirez, J.M.; Matallana, D.; Mbakile Mahlanza, L.; Marques Ton, A.M.; Tavares, R.M.; Miotto, E.C.; Muniz Terrera, G.; Muñoz Nevárez, L.A.; Orozco, D.; Okada de Oliveira, M.; Piguet, O.; Pintado Caipa, M.; Piña Escudero, S.D.; Schilling, L.P.; Rodrigues Palmeira, A.L.; Yassuda, M.S.; Santacruz Escudero, J.M.; Serafim, R.B.; Smid, J.; Slachevsky, A.; Serrano, C.; Soto Añari, M.; Takada, L.T.; Grinberg, L.T.; Teixeira, A.L.; Barbosa, M.T.; Trépel, D.; Ibanez, A.
Fecha:
2020
Resumen:
Across Latin American and Caribbean countries (LACs), the fight against dementia faces pressing challenges, such as heterogeneity, diversity, political instability, and socioeconomic disparities. These can be addressed more effectively in a collaborative setting that fosters open exchange of knowledge. In this work, the Latin American and Caribbean Consortium on Dementia (LAC-CD) proposes an agenda for integration to deliver a Knowledge to Action Framework (KtAF). First, we summarize evidence-based strategies (epidemiology, genetics, biomarkers, clinical trials, nonpharmacological interventions, networking, and translational research) and align them to current global strategies to translate regional knowledge into transformative actions. Then we characterize key sources of complexity (genetic isolates, admixture in populations, environmental factors, and barriers to effective interventions), map them to the above challenges, and provide the basic mosaics of knowledge toward a KtAF. Finally, we describe strategies supporting the knowledge creation stage that underpins the translational impact of KtAF.
Mostrar el registro completo del ítem
