Universidad Peruana Cayetano Heredia

Aging with HIV in Latin America and the Caribbean: a Systematic Review

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dc.contributor.author Cabrera, Diego M.
dc.contributor.author Diaz, Mónica M.
dc.contributor.author Grimshaw, Alyssa
dc.contributor.author Salvatierra Vega, Justina Luz
dc.contributor.author Garcia Funegra, Patricia Jannet
dc.contributor.author Hsieh, Evelyn
dc.date.accessioned 2021-04-13T20:51:02Z
dc.date.available 2021-04-13T20:51:02Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/9202
dc.description.abstract PURPOSE OF REVIEW: With the establishment of antiretroviral treatment (ART) programs in low- and middle-income countries, people with HIV (PWH) in Latin America and the Caribbean (LAC) are living longer, subsequently developing chronic non-communicable diseases (NCDs). Few studies focus on the impact of aging among older LAC PWH. This systematic review aims to fill this information gap and understand the burden of aging with HIV in LAC. We identified peer-reviewed literature published in English, Spanish, or Portuguese from several databases to assess currently available evidence on the burden of aging with HIV in LAC and selected six common NCDs found in older PWH (cardiovascular disease [CVD], bone and musculoskeletal [MSK] disorders, cancer, renal disease, neurocognitive impairment [NCI], and depression). RECENT FINDINGS: Of the 5942 publications reviewed, only 53 articles were found with populations 40 years and older or age-related findings (27 CVD, 13 NCI or depression, 6 MSK disorders, 4 renal disease, 3 cancer). Most (79%) publications were from Brazil with few longitudinal studies on aging with HIV. Prevalence of illnesses such as CVD, NCI, depression, or osteoporosis varied widely depending on the screening instrument utilized and geographic population surveyed. Age was a significant predictor of comorbidity in nearly all studies. Our results demonstrate the need for longitudinal studies and validated screening instruments appropriate for use among PWH in LAC. Understanding the mechanisms behind aging in HIV and the roles of sociocultural factors and genetic diversity specific to LAC is needed to appropriately manage chronic comorbidities as PWH age. en_US
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartofseries Current HIV/AIDS Reports
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Latin America en_US
dc.subject HIV en_US
dc.subject Aging en_US
dc.subject Morbidity en_US
dc.subject The Caribbean en_US
dc.title Aging with HIV in Latin America and the Caribbean: a Systematic Review en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1007/s11904-020-00538-7
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.relation.issn 1548-3576


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