Universidad Peruana Cayetano Heredia

Is exclusive breastfeeding for six-months protective against pediatric tuberculosis?

Mostrar el registro sencillo del ítem

dc.contributor.author Flores, Juan A.
dc.contributor.author Coit, Julia
dc.contributor.author Mendoza, Milagros
dc.contributor.author León Sandoval, Segundo Ramos
dc.contributor.author Konda, Kelika
dc.contributor.author Lecca, Leonid
dc.contributor.author Franke, Molly F.
dc.date.accessioned 2021-04-13T20:51:03Z
dc.date.available 2021-04-13T20:51:03Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/9212
dc.description.abstract Experts recommend exclusive breastfeeding from birth to six months because it protects against deadly childhood illness, including respiratory tract infections and diarrhea. We hypothesized that exclusive breastfeeding would decrease the risk of active tuberculosis (TB) in children. We analyzed cross-sectional data from 279 children in Lima, Peru aged 6 to 59 months with TB symptoms and a close adult contact with TB. Mothers self-reported breastfeeding, and children were evaluated for TB per national guidelines. To quantify the association between exclusive breastfeeding and TB, we estimated prevalence ratios using a generalized linear model with a log link, binomial distribution, and robust variance. Twenty-two percent of children were diagnosed with TB and 72% were exclusively breastfed for six months. We found no evidence that six months of exclusive breastfeeding was associated with TB disease in either bivariate analyses (prevalence ratio [PR] = 1.5; 95%CI = 0.8-2.5) or multivariable analyses adjusting for sex and socioeconomic status (adjusted PR = 1.6; 95%[CI] = 0.9-2.7). In post hoc analyses among children whose close TB contact was their mother, we found evidence of a weak positive association between breastfeeding and TB (aPR = 2.1; 95%[CI] = 0.9-4.9). This association was not apparent among children whose close contact was not the mother (aPR = 1.2; 95%[CI] = 0.6-2.4). Our results raise the possibility that children who are breastfed by mothers with TB may be at increased risk for TB, given the close contact. Due to the cross-sectional study design, these results should be interpreted with caution. If these findings are confirmed in longitudinal analyses, future interventions could aim to minimize TB transmission from mothers with TB to breastfeeding infants. en_US
dc.language.iso eng
dc.publisher Taylor and Francis
dc.relation.ispartofseries Global Health Action
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Mycobacterium tuberculosis en_US
dc.subject risk factor en_US
dc.subject child en_US
dc.subject infant en_US
dc.subject breastfeeding en_US
dc.title Is exclusive breastfeeding for six-months protective against pediatric tuberculosis? en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1080/16549716.2020.1861922
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1654-9880


Ficheros en el ítem

Ficheros Tamaño Formato Ver

No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

info:eu-repo/semantics/restrictedAccess Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/restrictedAccess

Buscar en el Repositorio


Listar

Panel de Control

Estadísticas