Universidad Peruana Cayetano Heredia
ST-segment elevation in patients with COVID-19: a systematic review
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| dc.contributor.author | Diaz Arocutipa, Carlos | |
| dc.contributor.author | Torres Valencia, Javier | |
| dc.contributor.author | Saucedo Chinchay, Jose | |
| dc.contributor.author | Cuevas, Cecilia | |
| dc.date.accessioned | 2021-04-13T20:51:03Z | |
| dc.date.available | 2021-04-13T20:51:03Z | |
| dc.date.issued | 2021 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12866/9225 | |
| dc.description.abstract | Coronavirus disease 2019 (COVID-19) can cause a wide range of cardiovascular diseases, including ST-segment elevation myocardial infarction (STEMI) and STEMI-mimickers (such as myocarditis, Takotsubo cardiomyopathy, among others). We performed a systematic review to summarize the clinical features, management, and outcomes of patients with COVID-19 who had ST-segment elevation. We searched electronic databases from inception to September 30, 2020 for studies that reported clinical data about COVID-19 patients with ST-segment elevation. Differences between patients with and without obstructive coronary artery disease (CAD) on coronary angiography were evaluated. Forty-two studies (35 case reports and seven case series) involving 161 patients were included. The mean age was 62.7 ± 13.6 years and 75% were men. The most frequent symptom was chest pain (78%). Eighty-three percent of patients had obstructive CAD. Patients with non-obstructive CAD had more diffuse ST-segment elevation (13% versus 1%, p = 0.03) and diffuse left ventricular wall-motion abnormality (23% versus 3%, p = 0.02) compared to obstructive CAD. In patients with previous coronary stent (n = 17), the 76% presented with stent thrombosis. In the majority of cases, the main reperfusion strategy was primary percutaneous coronary intervention instead of fibrinolysis. The in-hospital mortality was 30% without difference between patients with (30%) or without (31%) obstructive CAD. Our data suggest that a relatively high proportion of COVID-19 patients with ST-segment elevation had non-obstructive CAD. The prognosis was poor across groups. However, our findings are based on case reports and case series that should be confirmed in future studies. | en_US |
| dc.language.iso | eng | |
| dc.publisher | Springer | |
| dc.relation.ispartofseries | Journal of Thrombosis and Thrombolysis | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
| dc.subject | Systematic review | en_US |
| dc.subject | Coronavirus disease 2019 | en_US |
| dc.subject | Myocardial infarction | en_US |
| dc.subject | ST-segment elevation myocardial infarction | en_US |
| dc.title | ST-segment elevation in patients with COVID-19: a systematic review | en_US |
| dc.type | info:eu-repo/semantics/review | |
| dc.identifier.doi | https://doi.org/10.1007/s11239-021-02411-9 | |
| dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.02.04 | |
| dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.02.06 | |
| dc.relation.issn | 1573-742X |
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