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dc.contributor.author | Fano Sizgorich, Diego Alejandro | |
dc.contributor.author | Vásquez Velásquez, Cinthya | |
dc.contributor.author | Yucra, Sandra | |
dc.contributor.author | Vasquez Apéstegui, Bertha Vanessa | |
dc.contributor.author | Tokeshi, Patricio | |
dc.contributor.author | Aguilar, Julio | |
dc.contributor.author | Ramírez Atencio, Claudio | |
dc.contributor.author | Barr, Dana | |
dc.contributor.author | Gonzales Rengifo, Gustavo Francisco | |
dc.date.accessioned | 2021-04-13T20:51:05Z | |
dc.date.available | 2021-04-13T20:51:05Z | |
dc.date.issued | 2020 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/9253 | |
dc.description.abstract | Inorganic arsenic exposure has been linked to the development of several health conditions, including adverse birth outcomes; and around 150 million of people worldwide are exposed to levels above the WHO suggested limit of 10 μg/L. A recent risk assessment in pregnant women of Tacna, of this same population performed by our group, found that 70.25% were exposed to arsenic concentrations in drinking water ≥25 μg/L. The present study aimed to evaluate the relationship between prenatal total urinary arsenic (U-tAs) and inorganic arsenic (U-iAs) with adverse birth outcomes. A total of 147 pregnant women from the province of Tacna, Peru, during February - March, 2019, were evaluated for U-tAs and U-iAs exposure during their second trimester of pregnancy, while the birth records of their children were collected from the local hospital. The geometric mean U-tAs was 43.97 ± 25.88 μg/L (P(50) 22.30, range 5.99 - 181.94 μg/L) and U-iAs was 5.27 ± 2.91 μg/L. Controlling for maternal age, pre-pregnancy BMI, parity, mother's education and newborn sex, no relationship was observed between tertile of U-tAs and the birth outcomes considered, although we found an apparent but statistically non-significant dose-response relationship for small-for-gestational-age 2.38% ( 95% CI 0.003, 0.16), versus 7.32% (95% CI 0.02, 0.21%), versus 8.57% (0.03, 0.25%). This finding requires further evaluation considering other factors such as metabolic arsenic species, additional maternal covariates and ethnicity. | en_US |
dc.language.iso | eng | |
dc.publisher | Springer | |
dc.relation.ispartofseries | Exposure and Health | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | World Health Organization | en_US |
dc.subject | risk assessment | en_US |
dc.subject | child health | en_US |
dc.subject | drinking water | en_US |
dc.subject | pregnancy | en_US |
dc.subject | public health | en_US |
dc.subject | age structure | en_US |
dc.subject | arsenic | en_US |
dc.subject | Arsenic exposure | en_US |
dc.subject | Birth outcomes | en_US |
dc.subject | concentration (composition) | en_US |
dc.subject | dose-response relationship | en_US |
dc.subject | ethnicity | en_US |
dc.subject | spatiotemporal analysis | en_US |
dc.subject | Tacna | en_US |
dc.subject | Urinary arsenic | en_US |
dc.subject | womens health | en_US |
dc.title | Total Urinary Arsenic and Inorganic Arsenic Concentrations and Birth Outcomes in Pregnant Women of Tacna, Peru: A Cross-Sectional Study | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1007/s12403-020-00377-2 | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#5.07.01 | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.03.05 | |
dc.relation.issn | 2451-9685 |
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