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Fasciola hepatica Infection Risk for Adult Household Members with Children with Fascioliasis in Cusco, Peru

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dc.contributor.author Caravedo, Maria A.
dc.contributor.author Ramirez, Walter
dc.contributor.author Morales Fernández, María Luisa
dc.contributor.author Lopez, Martha
dc.contributor.author Janes, Claire E.
dc.contributor.author Bunag, Brittany A.
dc.contributor.author Mixon, Katie L.
dc.contributor.author White, A. Clinton
dc.contributor.author Tanabe, Melinda B.
dc.contributor.author Cabada, Miguel M.
dc.date.accessioned 2021-05-18T21:44:15Z
dc.date.available 2021-05-18T21:44:15Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/9372
dc.description.abstract Fasciola hepatica is highly prevalent in the highlands of Peru. School-age children have the greatest risk of infection. Mass treatment of at-risk populations has been proposed to control the infection and prevent complications. However, the decreasing effectiveness of triclabendazole raises concerns regarding this strategy. Previous studies reported aggregation of Fasciola infection among family members. This study aimed to determine the risk of fascioliasis among household members living with Fasciola-infected children identified through school-based testing. We conducted a cross-sectional study including adult members of households where children with and without fascioliasis were identified. Demographic, epidemiological, and socioeconomic information was collected. One blood sample was drawn to test for Fasciola antibodies, and three stool samples were collected for microscopy for Fasciola ova. We tested 326 adults from 213 households. Of these adult subjects, chronic fascioliasis (24 of 326, 7.4%) was the most common helminth infection. Thirty-nine subjects (12.7%) tested positive for Fasciola antibodies. Combining microscopy and serum antibody tests, 13.2% (43 of 326) had evidence of Fasciola infection. One third (104 of 326, 31.9%) of the participants lived with at least one child infected with Fasciola hepatica. Adults with fascioliasis were four times more likely to live with an infected child. Poverty and diet were associated with increased risk of Fasciola infection. Adults with fascioliasis were significantly more likely to live with Fasciola-infected children en_US
dc.language.iso eng
dc.publisher American Journal of Tropical Medicine and Hygiene
dc.relation.ispartofseries American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Fasciola hepatica en_US
dc.subject Infection en_US
dc.subject Household en_US
dc.subject Living with Children en_US
dc.subject Fascioliasis en_US
dc.subject Cusco en_US
dc.subject Peru en_US
dc.title Fasciola hepatica Infection Risk for Adult Household Members with Children with Fascioliasis in Cusco, Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.21-0131
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn 1476-1645


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