Universidad Peruana Cayetano Heredia

The association between asthma emergency department visits and satellite-derived PM(2.5) in Lima, Peru.

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dc.contributor.author Vu, Bryan N.
dc.contributor.author Tapia Aguirre, Vilma Lucrecia
dc.contributor.author Ebelt, Stefanie
dc.contributor.author Gonzales Rengifo, Gustavo Francisco
dc.contributor.author Liu, Yang
dc.contributor.author Steenland, Kyle
dc.date.accessioned 2021-05-18T21:44:17Z
dc.date.available 2021-05-18T21:44:17Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/9405
dc.description.abstract BACKGROUND: Asthma affects millions of people worldwide. Lima, Peru is one of the most polluted cities in the Americas but has insufficient ground PM(2.5) (particulate matter that are 2.5 microns or less in diameter) measurements to conduct epidemiologic studies regarding air pollution. PM(2.5) estimates from a satellite-driven model have recently been made, enabling a study between asthma and PM(2.5). OBJECTIVE: We conducted a daily time-series analysis to determine the association between asthma emergency department (ED) visits and estimated ambient PM(2.5) levels in Lima, Peru from 2010 to 2016. METHODS: We used Poisson generalized linear models to regress aggregated counts of asthma on district-level population weighted PM(2.5). Indicator variables for hospitals, districts, and day of week were included to account for spatial and temporal autocorrelation while assessing same day, previous day, day before previous and average across all 3-day exposures. We also included temperature and humidity to account for meteorology and used dichotomous percent poverty and gender variables to assess effect modification. RESULTS: There were 103,974 cases of asthma ED visits during the study period across 39 districts in Lima. We found a 3.7% (95% CI: 1.7%-5.8%) increase in ED visits for every interquartile range (IQR, 6.02 μg/m(3)) increase in PM(2.5) same day exposure with no age stratification. For the 0 to 18 years age group, we found a 4.5% (95% CI: 2.2%-6.8%) increase in ED visits for every IQR increase in PM(2.5) same day exposure. For the 19 to 64 years age group, we found a 6.0% (95% CI: 1.0%-11.0%) increase in ED visits for every IQR in average 3-day exposure. For the 65 years and up age group, we found a 16.0% (95% CI: 7.0%-24.0%) decrease in ED visits for every IQR increase in PM(2.5) average 3-day exposure, although the number of visits in this age group was low (4,488). We found no effect modification by SES or gender. DISCUSSION: Results from this study provide additional literature on use of satellite-driven exposure estimates in time-series analyses and evidence for the association between PM(2.5) and asthma in a low- and middle-income (LMIC) country en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Environmental Research
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject asthma en_US
dc.subject ED visits en_US
dc.subject PM(2.5) en_US
dc.subject remote sensing en_US
dc.subject time-series en_US
dc.title The association between asthma emergency department visits and satellite-derived PM(2.5) in Lima, Peru. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.envres.2021.111226
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.05.08
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1096-0953


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