Mostrar el registro sencillo del ítem
dc.contributor.author | Ugarte Gil, Manuel Francisco | |
dc.contributor.author | Pons-Estel, Guillermo J. | |
dc.contributor.author | Griffin, Russell | |
dc.contributor.author | Vilá, Luis M. | |
dc.contributor.author | Reveille, John D. | |
dc.contributor.author | Alarcón, Graciela S. | |
dc.date.accessioned | 2021-10-04T23:00:55Z | |
dc.date.available | 2021-10-04T23:00:55Z | |
dc.date.issued | 2021 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/9773 | |
dc.description.abstract | OBJECTIVE: To determine the difference in outcomes in patients who achieved or did not achieve the 2019 European Alliance of Associations for Rheumatology (EULAR)/American College of Rheumatology (ACR) criteria. METHODS: Patients from the LUpus in MInorities, NAture versus nurture (LUMINA) cohort were included. For these analyses, we compared those patients who achieved the 2019 EULAR/ACR criteria any time during follow-up to those who did not. The predefined outcomes were the last Systemic Lupus International Collaborating Clinics/ACR Damage Index (SDI) scores and survival. Univariable and multivariable negative binomial regression models were performed; adjustment models were based on a forward selection process. RESULTS: In total, 98 of 640 patients never achieved the 2019 EULAR/ACR criteria. There was no difference in mean baseline SDI score among the patients who did not achieve the criteria compared to those who did. Conversely, the mean ± SD SDI score at last visit was lower for those who never achieved the criteria (1.2 ± 1.7 versus 2.0 ± 2.3, P = 0.0004). In the final adjusted model, the SDI score at last visit was 31% lower for those who never achieved the criteria (P = 0.0077). These patients were also more likely to survive, but this was not statistically significant. CONCLUSION: In our cohort, patients who did not achieve the 2019 EULAR/ACR criteria accrued less damage, suggesting that these criteria could allow us to identify a subset of patients with more severe disease than allowed by previous criteria. | en_US |
dc.language.iso | eng | |
dc.publisher | Wiley | |
dc.relation.ispartofseries | Arthritis Care and Research | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | Humans | en_US |
dc.subject | Prognosis | en_US |
dc.subject | Rheumatology | en_US |
dc.subject | Severity of Illness Index | en_US |
dc.subject | Lupus Erythematosus | en_US |
dc.subject | Systemic/diagnosis/ethnology/therapy | en_US |
dc.subject | Predictive Value of Tests | en_US |
dc.subject | Time Factors | en_US |
dc.subject | United States/epidemiology | en_US |
dc.title | Achievement of the 2019 European Alliance of Associations for Rheumatology/American College of Rheumatology Criteria for Systemic Lupus Erythematosus and Amount of Damage Accrual: Results From a Multiethnic Multicenter Cohort | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1002/acr.24213 | |
dc.relation.issn | 2151-4658 |
Ficheros | Tamaño | Formato | Ver |
---|---|---|---|
No hay ficheros asociados a este ítem. |