Universidad Peruana Cayetano Heredia

Clinical, radiological and functional characteristics of pulmonary diseases among htlv-1 infected patients without prior active tuberculosis infection

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dc.contributor.author Cachay Figueroa, Rodrigo Antonio
dc.contributor.author Gil-Zacarias, M.
dc.contributor.author Watanabe-Tejada, T.
dc.contributor.author Schwalb Calderon, Alvaro
dc.contributor.author Mejía Cordero, Fernando Alonso
dc.contributor.author Gayoso, O.
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.date.accessioned 2021-10-04T23:00:56Z
dc.date.available 2021-10-04T23:00:56Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/9796
dc.description.abstract The lifelong infection with the human T lymphotropic virus type 1 (HTLV-1) has been associated with a variety of clinical manifestations; one of the less-explored is HTLV-1-associated pulmonary disease. Imaging of lung damage caused by the HTLV-1 hyperinflammatory cascade can be similar to sequelae from TB infection. Our study aims to describe the pulmonary lesions of HTLV-1-positive patients without past or current active TB and evaluate pulmonary function. We found that nine out of fourteen patients with no known TB disease history presented bronchiectasis, mainly found bilaterally while five presented pulmonary fibrosis. A normal pattern was found in most patients with a pulmonary functional test. Furthermore, there was no association between the PVL and the chest-CT scan findings, nor with spirometry results. However, the sample size was insufficient to conclude it en_US
dc.language.iso eng
dc.publisher MDPI
dc.relation.ispartofseries Pathogens
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject adult en_US
dc.subject Article en_US
dc.subject asthma en_US
dc.subject atelectasis en_US
dc.subject body mass en_US
dc.subject bronchiectasis en_US
dc.subject cross-sectional study en_US
dc.subject dermatitis en_US
dc.subject dyspnea en_US
dc.subject Epidemiology en_US
dc.subject female en_US
dc.subject forced expiratory volume en_US
dc.subject forced vital capacity en_US
dc.subject gastroesophageal reflux en_US
dc.subject ground glass opacity en_US
dc.subject heart failure en_US
dc.subject hospitalization en_US
dc.subject HTLV-1 en_US
dc.subject HTLV-1 infection en_US
dc.subject human en_US
dc.subject Human T-lymphotropic virus 1 en_US
dc.subject hypertension en_US
dc.subject hypothyroidism en_US
dc.subject losartan en_US
dc.subject lung disease en_US
dc.subject lung fibrosis en_US
dc.subject lung function test en_US
dc.subject lung injury en_US
dc.subject lung lesion en_US
dc.subject major clinical study en_US
dc.subject male en_US
dc.subject mixed connective tissue disease en_US
dc.subject non insulin dependent diabetes mellitus en_US
dc.subject obesity en_US
dc.subject oxygen saturation en_US
dc.subject physical examination en_US
dc.subject pneumoconiosis en_US
dc.subject Pulmonary disease en_US
dc.subject Pulmonary function en_US
dc.subject radiodiagnosis en_US
dc.subject sertraline en_US
dc.subject Sjoegren syndrome en_US
dc.subject spirometry en_US
dc.subject strongyloidiasis en_US
dc.subject tropical spastic paraparesis en_US
dc.subject tuberculosis en_US
dc.subject uveitis en_US
dc.subject vaccination en_US
dc.subject Western blotting en_US
dc.subject x-ray computed tomography en_US
dc.title Clinical, radiological and functional characteristics of pulmonary diseases among htlv-1 infected patients without prior active tuberculosis infection en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.3390/pathogens10070895
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 2076-0817


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