dc.contributor.author | Seiglie, Jacqueline A. | |
dc.contributor.author | Serván-Mori, Edson | |
dc.contributor.author | Manne-Goehler, Jennifer | |
dc.contributor.author | Meigs, James B. | |
dc.contributor.author | Miranda, J. Jaime | |
dc.contributor.author | Sosa-Rubí, Sandra G. | |
dc.contributor.author | Silverman-Retana, Omar | |
dc.contributor.author | Wexler, Deborah J. | |
dc.contributor.author | Wirtz, Verónica J. | |
dc.date.accessioned | 2021-10-04T23:00:57Z | |
dc.date.available | 2021-10-04T23:00:57Z | |
dc.date.issued | 2021 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/9813 | |
dc.description.abstract | Aims: We sought to investigate whether individuals with diabetes have a higher likelihood of testing positive for SARS-CoV-2, as a proxy for infection risk, than individuals without diabetes. Methods: We conducted a cross-sectional study of publicly available data among a Mexican population, totaling 2,314,022 adults ≥ 18 years who underwent SARS-CoV-2 testing between March 1 and December 20, 2020. We used 1:1 nearest neighborhood propensity score matching by diabetes status to account for confounding among those with and without diabetes. Results: In the overall study population, 1,057,779 (45.7%) individuals tested positive for SARS-CoV-2 and 270,486 (11.7%) self-reported diabetes. After propensity score matching, patient characteristics were well-balanced, with 150,487 patients in the diabetes group (mean [SD] age 55.9 [12.7] years; 51.3% women) and 150,487 patients in the no diabetes group (55.5 [13.3] years; 50.3% women). The strictest matching algorithm (1:1 nearest neighbor) showed that compared to individuals without diabetes, having diabetes was associated with 9.0% higher odds of having a positive SARS-CoV-2 test (OR 1.09 [95% CI: 1.08–1.10]). Conclusions: Presence of diabetes was associated with higher odds of testing positive for SARS-CoV-2, which could have important implications for risk mitigation efforts for people with diabetes at risk of SARS-CoV-2 infection | en_US |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.relation.ispartofseries | Diabetes Research and Clinical Practice | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | adult | en_US |
dc.subject | algorithm | en_US |
dc.subject | article | en_US |
dc.subject | controlled study | en_US |
dc.subject | COVID-19 testing | en_US |
dc.subject | cross-sectional study | en_US |
dc.subject | diabetic patient | en_US |
dc.subject | female | en_US |
dc.subject | human | en_US |
dc.subject | infection risk | en_US |
dc.subject | major clinical study | en_US |
dc.subject | male | en_US |
dc.subject | Mexico | en_US |
dc.subject | neighborhood | en_US |
dc.subject | propensity score | en_US |
dc.subject | risk factor | en_US |
dc.title | Diabetes mellitus as a risk factor for SARS-CoV-2 test positivity in Mexico: A propensity score matched study | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1016/j.diabres.2021.108953 | |
dc.relation.issn | 1872-8227 |
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