Universidad Peruana Cayetano Heredia

Multimorbidity in Latin America and the Caribbean: A systematic review and meta-analysis

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dc.contributor.author Huaquiá-Diáz, A.M.
dc.contributor.author Chalán-Dávila, T.S.
dc.contributor.author Carrillo Larco, Rodrigo Martín
dc.contributor.author Bernabé Ortiz, Antonio
dc.date.accessioned 2021-10-04T23:00:59Z
dc.date.available 2021-10-04T23:00:59Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/9857
dc.description.abstract Objective To estimate the pooled prevalence of multimorbidity (≥2 non-communicable diseases in the same individual) among adults of the general population of Latin American and the Caribbean (LAC). Design Systematic review and meta-analysis. Data sources MEDLINE, Embase, Global Health, Scopus and LILACS up to 1 July 2020. Eligibility criteria for selecting studies The outcome was the prevalence of multimorbidity. Reports were selected whether they enrolled adult individuals (age ≥18 years) from the general population. Data extraction and synthesis Reviewers extracted relevant data and assessed risk of bias independently. A random-effects meta-analysis was conducted to report pooled prevalence estimates of multimorbidity; pooled estimates by pre-specified subgroups (eg, national studies) were also pursued. Results From 5830 results, we selected 28 reports, mostly from Brazil and 16 were based on a nationally representative sample. From the 28 selected reports, 26 were further included in the meta-analysis revealing a pooled multimorbidity prevalence of 43% (95% CI: 35% to 51%; I 2: 99.9%). When only reports with a nationally representative sample were combined, the pooled prevalence was 37% (95% CI: 27% to 47%; I 2: 99.9%). When the ascertainment of multimorbidity was based on self-reports alone, the pooled prevalence was 40% (95% CI: 31% to 48%; I 2: 99.9%); this raised to 52% (95% CI: 33% to 70%; I 2: 99.9%) for reports including self-reported and objective diagnosis. Conclusions Our results complement and advance those from global efforts by incorporating much more reports from LAC. We revealed a larger presence of multimorbidity in LAC than previously reported en_US
dc.language.iso eng
dc.publisher BMJ Publishing Group
dc.relation.ispartofseries BMJ Open
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject adolescent en_US
dc.subject Adolescent en_US
dc.subject Brazil en_US
dc.subject Caribbean en_US
dc.subject Caribbean Region en_US
dc.subject diabetes & endocrinology en_US
dc.subject epidemiology en_US
dc.subject human en_US
dc.subject Humans en_US
dc.subject hypertension en_US
dc.subject Latin America en_US
dc.subject meta analysis en_US
dc.subject Multimorbidity en_US
dc.subject multiple chronic conditions en_US
dc.subject prevalence en_US
dc.subject Prevalence en_US
dc.subject public health en_US
dc.subject South and Central America en_US
dc.title Multimorbidity in Latin America and the Caribbean: A systematic review and meta-analysis en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1136/bmjopen-2021-050409
dc.relation.issn 2044-6055


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