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  • Cardiometabolic correlates of sleep disordered breathing in Andean highlanders 
    Pham, Luu V.; Miele, Catherine H.; Schwartz, Noah G.; Arias, Rafael S.; Rattner, Adi; Gilman, Robert Hugh; Miranda, J. Jaime; Polotsky, Vsevolod Y.; Checkley, William; Schwartz, Alan R. (European Respiratory Society, 2017)
    Associations between sleep disordered breathing (SDB) and cardiometabolic outcomes have not been examined in highlanders.We performed nocturnal polygraphy in Peruvian highlanders (3825 m). Multivariable linear regression ...
  • Case-Case Analysis Using 7 Years of Travelers' Diarrhea Surveillance Data: Preventive and Travel Medicine Applications in Cusco, Peru 
    Jennings, Mary Carol; Tilley, Drake H.; Ballard, Sarah-Blythe; Villanueva, Miguel; Maldonado Costa, Fernando; Lopez, Martha; Steinberg, Hannah E.; Luna, C. Giannina; Meza, Rina; Silva, Maria E.; Gilman, Robert Hugh; Simons, Mark P.; Maves, Ryan C.; Cabada, Miguel M. (American Society of Tropical Medicine and Hygiene, 2017)
    In Cusco, Peru, and South America in general, there is a dearth of travelers' diarrhea (TD) data concerning the clinical features associated with enteropathogen-specific infections and destination-specific risk behaviors. ...
  • Characteristics Associated With Antihypertensive Treatment and Blood Pressure Control: A Population-Based Follow-Up Study in Peru 
    Zavala-Loayza, J. Alfredo; Pastorius-Benziger, Catherine; Cárdenas García-Santillán, María Kathia; Carrillo Larco, Rodrigo Martín; Bernabé Ortiz, Antonio; Gilman, Robert Hugh; Checkley, William; Miranda, J. Jaime (Elsevier, 2016)
    BACKGROUND: Over one-quarter of the world's adult population has hypertension, yet achieving adequate treatment or control targets remains a challenge. OBJECTIVE: This study sought to identify, longitudinally, characteristics ...
  • Chronic respiratory disease and high altitude are associated with depressive symptoms in four diverse settings 
    Zaeh, S.; Miele, C. H.; Putcha, N.; Gilman, Robert Hugh; Miranda, J. Jaime; Bernabé Ortiz, Antonio; Wise, R. A.; Checkley, W. (International Union Against Tuberculosis and Lung Disease, 2016)
    SETTING: Depression is a prevalent comorbidity of chronic respiratory disease (CRD), and may indicate worse clinical outcomes. The relationship between depression and living with chronic hypoxia due to CRD or residence at ...
  • Clinical and Molecular Features of Late Onset Huntington Disease in a Peruvian Cohort 
    Cornejo-Olivas, M.R.; Inca-Martinez, M.A.; Espinoza Huertas, Keren Antonieta; Veliz-Otani, D.; Velit-Salazar, M.R.; Marca, V.; Ortega, O.; Cornejo-Herrera, I.F.; Lindo-Samanamud, S.; Mora-Alferez, P.; Mazzetti, P. (IOS Press, 2015)
    Background: Late onset cases of Huntington disease (HD), with onset ≥60 years, account for up to 20% of HD cases worldwide. Clinical features include mild motor dysfunction with slow progression and cognitive impairment, ...
  • Clonidine in patients undergoing noncardiac surgery 
    Devereaux, P.J.; Sessler, D.I.; Leslie, K.; Kurz, A.; Mrkobrada, M.; Alonso-Coello, P.; Villar, J.C.; Sigamani, A.; Biccard, B.M.; Meyhoff, C.S.; Parlow, J.L.; Guyatt, G.; Robinson, A.; Garg, A.X.; Rodseth, R.N.; Botto, F.; Lurati Buse, G.; Xavier, D.; Chan, M.T.V.; Tiboni, M.; Cook, D.; Kumar, P.A.; Forget, P.; Málaga Rodríguez, Germán Javier; Fleischmann, E.; Amir, M.; Eikelboom, J.; Mizera, R.; Torres, D.; Wang, C.Y.; VanHelder, T.; Paniagua, P.; Berwanger, O.; Srinathan, S.; Graham, M.; Pasin, L.; Le Manach, Y.; Gao, P.; Pogue, J.; Whitlock, R.; Lamy, A.; Kearon, C.; Chow, C.; Pettit, S.; Chrolavicius, S.; Yusuf, S. (Massachusetts Medical Society, 2014)
    BACKGROUND: Marked activation of the sympathetic nervous system occurs during and after non-cardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may prevent perioperative myocardial infarction and ...
  • Cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in Peru 
    Lazo Porras, María de los Ángeles; Ortiz-Soriano, Victor; Moscoso-Porras, Miguel; Runzer-Colmenares, Fernando M.; Málaga Rodríguez, Germán Javier; Miranda, J. Jaime (BioMed Central, 2017)
    BACKGROUND: Previous studies have shown that hypertension is a risk factor for cognitive impairment, but whether this association is also present in extremely poor populations in Low Middle Income Countries settings remains ...
  • Commentary to the article: Nutritional status, physical performance, and disability in the elderly of the Peruvian Andes 
    Ortiz, Pedro J.; Tello, Tania (Springer, 2017)
    Tramontano et al. evaluated the relationship between nutritional status, physical performance, and disability in elderly people of the Peruvian Andes, finding that poor nutritional status was significantly associated with ...
  • A comparative cross-cultural study of the prevalence of late life depression in low and middle income countries 
    Guerra Arteaga, Mariella; Prina, A.M.; Ferri, C.P.; Acosta, D.; Gallardo, S.; Huang, Y.; Jacob, K.S.; Jimenez-Velazquez, I.Z.; Llibre Rodriguez, J.J.; Liu, Z.; Salas, A.; Sosa, A.L.; Williams, J.D.; Uwakwe, R.; Prince, M. (Elsevier, 2016)
    Background: Current estimates of the prevalence of depression in later life mostly arise from studies carried out in Europe, North America and Asia. In this study we aimed to measure the prevalence of depression using a ...
  • Comparison of Nonblood-Based and Blood-Based Total CV Risk Scores in Global Populations 
    Gaziano, Thomas-A.; Abrahams-Gessel, Shafika; Alam, Sartaj; Alam, Dewan; Ali, Mohammed; Bloomfield, Gerald; Carrillo Larco, Rodrigo Martín; Dorairaj, Prabhakaran; Gutierrez, Laura; Irazola, Vilma; Levitt, Naomi-S.; Miranda, J. Jaime; Bernabé Ortiz, Antonio; Pandya, Ankur; Rubinstein, Adolfo; Steyn, Krisela; Xavier, Denis; Yan, Lijing-L. (Elsevier, 2016)
    BACKGROUND: Cost-effective primary prevention of cardiovascular disease (CVD) in low- and middle-income countries requires accurate risk assessment. Laboratory-based risk tools currently used in high-income countries are ...
  • Contribution of modifiable risk factors for hypertension and type-2 diabetes in Peruvian resource-limited settings 
    Bernabé Ortiz, Antonio; Carrillo Larco, Rodrigo Martín; Gilman, Robert Hugh; Checkley, William; Smeeth, Liam; Miranda, J. Jaime; CRONICAS Cohort Study Group (BMJ Publishing Group, 2015)
    BACKGROUND: It is important to understand the local burden of non-communicable diseases including within-country heterogeneity. The aim of this study was to characterise hypertension and type-2 diabetes profiles across ...
  • Coronary atherosclerosis in indigenous South American Tsimane: a cross-sectional cohort study 
    Kaplan, Hillard; Thompson, Randall C.; Trumble, Benjamin C.; Wann, L. Samuel; Allam, Adel H.; Beheim, Bret; Frohlich, Bruno; Sutherland, M. Linda; Sutherland, James D.; Stieglitz, Jonathan; Rodriguez, Daniel Eid; Michalik, David E.; Rowan, Chris J.; Lombardi, Guido P.; Bedi, Ram; Garcia, Angela R.; Min, James K.; Narula, Jagat; Finch, Caleb E.; Gurven, Michael; Thomas, Gregory S. (Elsevier, 2017)
    BACKGROUND: Conventional coronary artery disease risk factors might potentially explain at least 90% of the attributable risk of coronary artery disease. To better understand the association between the pre-industrial ...
  • The cost of illness attributable to diabetic foot and cost-effectiveness of secondary prevention in Peru 
    Cárdenas García-Santillán, María Kathia; Mirelman, Andrew J.; Galvin, Cooper J.; Lazo Porras, María de los Ángeles; Pinto, Miguel; Miranda, J. Jaime; Gilman, Robert Hugh (BioMed Central, 2015)
    BACKGROUND: Diabetes mellitus is a public health challenge worldwide, and roughly 25% of patients with diabetes in developing countries will develop at least one foot ulcer during their lifetime. The gravest outcome of an ...
  • Cross-Sectional Comparison of Sleep-Disordered Breathing in Native Peruvian Highlanders and Lowlanders 
    Pham, Luu V.; Meinzen, Christopher; Arias, Rafael S.; Schwartz, Noah G.; Rattner, Adi; Miele, Catherine H.; Smith, Philip L.; Schneider, Hartmut; Miranda, J. Jaime; Gilman, Robert Hugh; Polotsky, Vsevolod Y.; Checkley, William; Schwartz, Alan R. (Mary Ann Liebert, 2017)
    BACKGROUND: Altitude can accentuate sleep disordered breathing (SDB), which has been linked to cardiovascular and metabolic diseases. SDB in highlanders has not been characterized in large controlled studies. The purpose ...
  • Cutaneous leishmaniasis treatment and therapeutic outcomes in special populations: A collaborative retrospective study. 
    Castro, Maria Del Mar; Rode, Joelle; Machado, Paulo R L; Llanos Cuentas, Elmer Alejandro; Hueb, Marcia; Cota, Glaucia; Rojas, Isis Valentina; Orobio, Yenifer; Oviedo Sarmiento, Oscar; Rojas, Ernesto; Quintero, Juliana; Pimentel, Maria Ines Fernandes; Soto, Jaime; Suprien, Carvel; Alvarez Romero, Fiorela Yuli; Ramos Ttito, Ana Pilar; Arantes, Rayssa Basilio Dos Santos; da Silva, Rosiana Estefane; Arenas, Claudia Marcela; Vélez, Ivan Dario; Lyra, Marcelo Rosandiski; Saravia, Nancy Gore; Arana, Byron; Alexander, Neal (Public Library of Science, 2023)
    BACKGROUND: Treatment guidance for children and older adult patients affected by cutaneous leishmaniasis (CL) is unclear due to limited representation of these groups in clinical trials.METHODS: We conducted a collaborative ...
  • Cysticerci-related single parenchymal brain enhancing lesions in non-endemic countries 
    Del Brutto, O.H.; Nash, T.E.; García Lescano, Héctor Hugo (Elsevier, 2012)
    Objective: Review of case reports and case series of patients with single cysticercus granulomas in non-endemic countries to determine the characteristics of this form of neurocysticercosis in these regions. Methods: MEDLINE ...
  • Daily smoking and 4-year caries increment in Finnish adults 
    Bernabé, Eduardo; Delgado-Angulo, Elsa K.; Vehkalahti, Miira M.; Aromaa, Arpo; Suominen, Anna L. (Wiley, 2014)
    Objectives: Although the harmful effects of smoking on periodontal disease and oral cancer are now indisputable, its effect on dental caries is less well known. This study assessed whether daily smoking predicts caries ...
  • Delivery of Type 2 diabetes care in low- and middle-income countries: lessons from Lima, Peru 
    Cárdenas García-Santillán, María Kathia; Miranda, J. Jaime; Beran, D. (Wiley, 2016)
    AIMS: The health system's response is crucial to addressing the increasing burden of diabetes, particularly that affecting low- and middle-income countries. This study aims to assess the facilitators and barriers that help ...
  • Dengue incidence and sociodemographic conditions in Pucallpa, Peruvian Amazon: what role for modification of the dengue-temperature relationship? 
    Charette, Margot; Berrang-Ford, Lea; Coomes, Oliver; Llanos Cuentas, Elmer Alejandro; Cárcamo Cavagnaro, César Paul Eugenio; Kulkarni, Manisha; Harper, Sherilee L. (American Society of Tropical Medicine and Hygiene, 2020)
    Dengue is a climate-sensitive disease with an increasing global burden. Although the relationship between meteorological conditions and dengue incidence is well established, less is known about the modifying nature of ...
  • Dengue Knowledge and Preventive Practices in Iquitos, Peru 
    Paz-Soldan Parlette, Valerie Andrea; Morrison, Amy C.; Cordova Lopez, Jhonny J.; Lenhart, Audrey; Scott, Thomas W.; Elder, John P.; Sihuincha, Moises; Kochel, Tadeusz J.; Halsey, Eric S.; Astete, Helvio; McCall, Philip J. (American Society of Tropical Medicine and Hygiene, 2015)
    As part of a cluster-randomized trial to evaluate insecticide-treated curtains for dengue prevention in Iquitos, Peru, we surveyed 1,333 study participants to examine knowledge and reported practices associated with dengue ...

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