Listar por autor "Coronel, Jorge"

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  • Protocol for studying cough frequency in people with pulmonary tuberculosis 
    Proaño, Alvaro; Bravard, Marjory A.; Tracey, Brian H.; Lopez, Jose W.; Comina, German; Zimic-Peralta, Mirko Juan; Coronel, Jorge; Lee, Gwenyth O'Neil; Caviedes, Luz; Cabrera, Jose Luis; Salas, Antonio; Ticona, Eduardo; Kirwan, Daniela E.; Friedland, Jon S.; Evans, Carlton Anthony William; Moore, David Alexander James; Gilman, Robert Hugh (BMJ Publishing Group, 2016)
    INTRODUCTION: Cough is a key symptom of tuberculosis (TB) as well as the main cause of transmission. However, a recent literature review found that cough frequency (number of coughs per hour) in patients with TB has only ...
  • A quantitative adaptation of the Wayne test for pyrazinamide resistance 
    Meinzen, Christopher; Proano, Alvaro; Gilman, Robert Hugh; Caviedes, Luz; Coronel, Jorge; Zimic-Peralta, Mirko Juan; Sheen Cortavarria, Patricia (Elsevier, 2016)
    BACKGROUND: Pyrazinamide (PZA) is the most important drug against the latent stage of tuberculosis (TB) and is used in both first and second line treatment regimens. The continued increase in multi-drug resistant TB and ...
  • Rationing tests for drug-resistant tuberculosis - who are we prepared to miss? 
    Martin, Laura J.; Roper, Martha H.; Grandjean, Louis; Gilman, Robert Hugh; Coronel, Jorge; Caviedes, Luz; Friedland, Jon S.; Moore, David Alexander James (BioMed Central, 2016)
    Background: Early identification of patients with drug-resistant tuberculosis (DR-TB) increases the likelihood of treatment success and interrupts transmission. Resource-constrained settings use risk profiling to ration ...
  • Second-line anti-tuberculosis drug concentrations for susceptibility testing in the MODS assay 
    Fitzwater, Sean Patrick; Sechler, G. Andrew; Jave, Oswaldo; Coronel, Jorge; Mendoza, Alberto; Gilman, Robert Hugh; Friedland, Jon S.; Moore, David Alexander James (European Respiratory Society, 2013)
    Multidrug-resistant tuberculosis (TB) threatens TB control worldwide. The microscopic observation drug susceptibility (MODS) assay is a low-cost, high-performance TB diagnostic tool for rapid liquid culture and direct ...
  • Transmission of Multidrug-Resistant and Drug-Susceptible Tuberculosis within Households: A Prospective Cohort Study 
    Grandjean, Louis; Gilman, Robert Hugh; Martin, Laura; Soto, Esther; Castro, Beatriz; Lopez, Sonia; Coronel, Jorge; Castillo, Edith; Alarcon, Valentina; Lopez, Virginia; San Miguel, Angela; Quispe, Neyda; Asencios, Luis; Dye, Christopher; Moore, David Alexander James (Public Library of Science, 2015)
    BACKGROUND: The "fitness" of an infectious pathogen is defined as the ability of the pathogen to survive, reproduce, be transmitted, and cause disease. The fitness of multidrug-resistant tuberculosis (MDRTB) relative to ...
  • Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity 
    Paris, Luisa; Magni, Ruben; Zaidi, Fatima; Araujo, Robyn; Saini, Neal; Harpole, Michael; Coronel, Jorge; Kirwan, Daniela E.; Steinberg, Hannah; Gilman, Robert Hugh; Petricoin, Emanuel F.; Nisini, Roberto; Luchini, Alessandra; Liotta, Lance (American Association for the Advancement of Science, 2017)
    An accurate urine test for pulmonary tuberculosis (TB), affecting 9.6 million patients worldwide, is critically needed for surveillance and treatment management. Past attempts failed to reliably detect the mycobacterial ...

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