Listar por autor "Acuña-Alonzo, V."

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  • Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium 
    Fernández-Rhodes, L.; Graff, M.; Buchanan, V.L.; Justice, A.E.; Highland, H.M.; Guo, X.; Zhu, W.; Chen, H.-H.; Young, K.L.; Adhikari, K.; Palmer, N.D.; Below, J.E.; Bradfield, J.; Pereira, A.C.; Glover, L.S.; Kim, D.; Lilly, A.G.; Shrestha, P.; Thomas, A.G.; Zhang, X.; Chen, M.; Chiang, C.W.K.; Pulit, S.; Horimoto, A.; Krieger, J.E.; Guindo-Martínez, M.; Preuss, M.; Schumann, C.; Smit, R.A.J.; Torres-Mejía, G.; Acuña-Alonzo, V.; Bedoya, G.; Bortolini, M.-C.; Canizales-Quinteros, S.; Gallo López-Aliaga, Carla Maria; González-José, R.; Poletti, G.; Rothhammer, F.; Hakonarson, H.; Igo, R.; Adler, S.G.; Iyengar, S.K.; Nicholas, S.B.; Gogarten, S.M.; Isasi, C.R.; Papnicolaou, G.; Stilp, A.M.; Qi, Q.; Kho, M.; Smith, J.A.; Langefeld, C.D.; Wagenknecht, L.; Mckean-Cowdin, R.; Gao, X.R.; Nousome, D.; Conti, D.V.; Feng, Y.; Allison, M.A.; Arzumanyan, Z.; Buchanan, T.A.; Ida Chen, Y.-D.; Genter, P.M.; Goodarzi, M.O.; Hai, Y.; Hsueh, W.; Ipp, E.; Kandeel, F.R.; Lam, K.; Li, X.; Nadler, J.L.; Raffel, L.J.; Roll, K.; Sandow, K.; Tan, J.; Taylor, K.D.; Xiang, A.H.; Yao, J.; Audirac-Chalifour, A.; de Jesus Peralta Romero, J.; Hartwig, F.; Horta, B.; Blangero, J.; Curran, J.E.; Duggirala, R.; Lehman, D.E.; Puppala, S.; Fejerman, L.; John, E.M.; Aguilar-Salinas, C.; Burtt, N.P.; Florez, J.C.; García-Ortíz, H.; González-Villalpando, C.; Mercader, J.; Orozco, L.; Tusié-Luna, T.; Blanco, E.; Gahagan, S.; Cox, N.J.; Hanis, C.; Butte, N.F.; Cole, S.A.; Comuzzie, A.G.; Voruganti, V.S.; Rohde, R.; Wang, Y.; Sofer, T.; Ziv, E.; Grant, S.F.A.; Ruiz-Linares, A.; Rotter, J.I.; Haiman, C.A.; Parra, E.J.; Cruz, M.; Loos, R.J.F.; North, K.E. (Elsevier, 2022)
    Hispanic/Latinos have been underrepresented in genome-wide association studies (GWAS) for anthropometric traits despite their notable anthropometric variability, ancestry proportions, and high burden of growth stunting and ...
  • Disentangling Signatures of Selection Before and After European Colonization in Latin Americans 
    Mendoza-Revilla, J.; Chacón-Duque, J.C.; Fuentes-Guajardo, M.; Ormond, L.; Wang, K.; Hurtado, M.; Villegas, V.; Granja, V.; Acuña-Alonzo, V.; Jaramillo, C.; Arias, W.; Barquera, R.; Gómez-Valdés, J.; Villamil-Ramírez, H.; Silva de Cerqueira, C.C.; Badillo Rivera, K.M.; Nieves-Colón, M.A.; Gignoux, C.R.; Wojcik, G.L.; Moreno-Estrada, A.; Hünemeier, T.; Ramallo, V.; Schuler-Faccini, L.; Gonzalez-José, R.; Bortolini, M.-C.; Canizales-Quinteros, S.; Gallo López-Aliaga, Carla Maria; Poletti, G.; Bedoya, G.; Rothhammer, F.; Balding, D.; Fumagalli, M.; Adhikari, K.; Ruiz-Linares, A.; Hellenthal, G. (Oxford University Press, 2022)
    Throughout human evolutionary history, large-scale migrations have led to intermixing (i.e., admixture) between previously separated human groups. Although classical and recent work have shown that studying admixture can ...
  • Facial asymmetry and genetic ancestry in Latin American admixed populations 
    Quinto-Sánchez, Mirsha; Adhikari, K.; Acuña-Alonzo, V.; Cintas, C.; Silva De Cerqueira, C.C.; Ramallo, V.; Castillo, L.; Farrera, A.; Jaramillo, C.; Arias, W.; Fuentes, M.; Everardo, P.; De Avila, F.; Gomez-Valdés, J.; Hünemeier, T.; Gibbon, S.; Gallo López-Aliaga, Carla Maria; Poletti, Giovanni; Rosique, J.; Bortolini, M.C.; Canizales-Quinteros, S.; Rothhammer, F.; Bedoya, G.; Ruiz-Linares, A.; González-José, R. (Wiley, 2015)
    Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants of ...
  • A genome-wide association study identifies novel gene associations with facial skin wrinkling and mole count in Latin Americans 
    Chen, Yingjie; André, Mathilde; Adhikari, K.; Blin, M.; Bonfante, B.; Mendoza-Revilla, J.; Fuentes-Guajardo, M.; Palmal, S.; Chacón-Duque, J. C.; Hurtado, M.; Villegas, V.; Granja, V.; Jaramillo, C.; Arias, W.; Lozano, R. B.; Everardo-Martínez, P.; Gómez-Valdés, J.; Villamil-Ramírez, H.; de Cerqueira, C. C. S.; Hünemeier, T.; Ramallo, V.; Gonzalez-José, R.; Schüler-Faccini, L.; Bortolini, M.-C.; Acuña-Alonzo, V.; Canizales-Quinteros, S.; Gallo López-Aliaga, Carla Maria; Poletti, G.; Bedoya, G.; Rothhammer, F.; Balding, D.; Tobin, D. J.; Wang, S.; Faux, P.; Ruiz-Linares, A. (Wiley, 2021)
    BACKGROUND: Genome-wide association studies (GWAS) have identified genes influencing skin ageing and mole count in Europeans but little is known about the relevance of these (or other genes) in non-Europeans. OBJECTIVE: ...
  • A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia 
    Adhikari, K.; Mendoza-Revilla, J.; Sohail, A.; Fuentes-Guajardo, M.; Lampert, J.; Chacón-Duque, J.C.; Hurtado, M.; Villegas, V.; Granja, V.; Acuña-Alonzo, V.; Jaramillo, C.; Arias, W.; Lozano, R.B.; Everardo, P.; Gómez-Valdés, J.; Villamil-Ramírez, H.; Silva de Cerqueira, C.C.; Hunemeier, T.; Ramallo, V.; Schuler-Faccini, L.; Salzano, F.M.; Gonzalez-José, R.; Bortolini, M.-C.; Canizales-Quinteros, S.; Gallo López-Aliaga, Carla Maria; Poletti, G.; Bedoya, G.; Rothhammer, F.; Tobin, D.J.; Fumagalli, M.; Balding, D.; Ruiz-Linares, A. (Springer Nature, 2019)
    We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions. These include one novel locus for skin pigmentation ...
  • The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure 
    Barquera, R.; Hernández-Zaragoza, D.I.; Bravo-Acevedo, A.; Arrieta-Bolaños, E.; Clayton, S.; Acuña-Alonzo, V.; Martínez-Álvarez, J.C.; López-Gil, C.; Adalid-Sáinz, C.; Vega-Martínez, M.D.R.; Escobedo-Ruíz, A.; Juárez-Cortés, E.D.; Immel, A.; Pacheco-Ubaldo, H.; González-Medina, L.; Lona-Sánchez, A.; Lara-Riegos, J.; Sánchez-Fernández, M.G.D.J.; Díaz-López, R.; Guizar-López, G.U.; Medina-Escobedo, C.E.; Arrazola-García, M.A.; Montiel-Hernández, G.D.; Hernández-Hernández, O.; Ramos-de la Cruz, F.D.R.; Juárez-Nicolás, F.; Pantoja-Torres, J.A.; Rodríguez-Munguía, T.J.; Juárez-Barreto, V.; Delgado-Aguirre, H.; Escutia-González, Ariadna Berenice; Goné-Vázquez, I.; Benítez-Arvizu, G.; Arellano-Prado, F.P.; García-Arias, V.E.; Rodríguez-López, M.E.; Méndez-Mani, P.; García-Álvarez, R.; González-Martínez, M.D.R.; Aquino-Rubio, G.; Escareño-Montiel, N.; Vázquez-Castillo, T.V.; Uribe-Duarte, M.G.; Ruíz-Corral, M.D.J.; Ortega-Yáñez, A.; Bernal-Felipe, N.; Gómez-Navarro, B.; Arriaga-Perea, A.J.; Martínez-Bezies, V.; Macías-Medrano, R.M.; Aguilar-Campos, J.A.; Solís-Martínez, R.; Serrano-Osuna, R.; Sandoval-Sandoval, M.J.; Jaramillo-Rodríguez, Y.; Salgado-Adame, A.; Juárez-de la Cruz, F.; Novelo-Garza, B.; Pavón-Vargas, M.D.L.Á.; Salgado-Galicia, N.; Bortolini, M.C.; Gallo López-Aliaga, Carla Maria; Bedoya, G.; Rothhammer, F.; González-José, R.; Ruiz-Linares, A.; Canizales-Quinteros, S.; Romero-Hidalgo, S.; Krause, J.; Zúñiga, J.; Yunis, E.J.; Bekker-Méndez, C.; Granados, J. (Elsevier, 2020)
    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) allele groups and alleles by PCR-SSP based typing in a total of 15,318 mixed ancestry Mexicans from all the states of the country divided into 78 sample ...
  • Native American ancestry significantly contributes to neuromyelitis optica susceptibility in the admixed Mexican population 
    Romero-Hidalgo, S.; Flores-Rivera, J.; Rivas-Alonso, V.; Barquera, R.; Villarreal-Molina, M.T.; Antuna-Puente, B.; Macias-Kauffer, L.R.; Villalobos-Comparán, M.; Ortiz-Maldonado, J.; Yu, N.; Lebedeva, T.V.; Alosco, S.M.; García-Rodríguez, J.D.; González-Torres, C.; Rosas-Madrigal, S.; Ordoñez, G.; Guerrero-Camacho, J.L.; Treviño-Frenk, I.; Escamilla-Tilch, M.; García-Lechuga, M.; Tovar-Méndez, V.H.; Pacheco-Ubaldo, H.; Acuña-Alonzo, V.; Bortolini, M.-C.; Gallo López-Aliaga, Carla Maria; Bedoya, G.; Rothhammer, F.; González-Jose, R.; Ruiz-Linares, A.; Canizales-Quinteros, S.; Yunis, E.; Granados, J.; Corona, T. (Springer Nature, 2020)
    Neuromyelitis Optica (NMO) is an autoimmune disease with a higher prevalence in non-European populations. Because the Mexican population resulted from the admixture between mainly Native American and European populations, ...
  • Reconstructing Native American population history 
    Reich, D.; Patterson, N.; Campbell, D.; Tandon, A.; Mazieres, S.; Ray, N.; Parra, M.V.; Rojas, W.; Duque, C.; Mesa, N.; García, L.F.; Triana, O.; Blair, S.; Maestre, A.; Dib, J.C.; Bravi, C.M.; Bailliet, G.; Corach, D.; Hünemeier, T.; Bortolini, M.C.; Salzano, F.M.; Petzl-Erler, M.L.; Acuña-Alonzo, V.; Aguilar-Salinas, C.; Canizales-Quinteros, S.; Tusié-Luna, T.; Riba, L.; Rodríguez-Cruz, M.; Lopez-Alarcón, M.; Coral-Vazquez, R.; Canto-Cetina, T.; Silva-Zolezzi, I.; Fernandez-Lopez, J.C.; Contreras, A.V.; Jimenez-Sanchez, G.; Gómez-Vázquez, M.J.; Molina, J.; Carracedo, A.; Salas, A.; Gallo López-Aliaga, Carla Maria; Poletti, G.; Witonsky, D.B.; Alkorta-Aranburu, G.; Sukernik, R.I.; Osipova, L.; Fedorova, S.A.; Vasquez, R.; Villena, M.; Moreau, C.; Barrantes, R.; Pauls, D.; Excoffier, L.; Bedoya, G.; Rothhammer, F.; Dugoujon, J.-M.; Larrouy, G.; Klitz, W.; Labuda, D.; Kidd, J.; Kidd, K.; Di Rienzo, A.; Freimer, N.B.; Price, A.L.; Ruiz-Linares, A. (Springer Nature, 2012)
    The peopling of the Americas has been the subject of extensive genetic, archaeological and linguistic research; however, central questions remain unresolved. One contentious issue is whether the settlement occurred by means ...

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