Listar por autor "Ainslie, P.N."

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Acid-base balance at high altitude in lowlanders and indigenous highlanders

Tymko, M.M.; Willie, C.K.; Howe, C.A.; Hoiland, R.L.; Stone, R.M.; Tymko, K.; Tymko, C.; MacLeod, D.; Anholm, J.D.; Gasho, C.; Villafuerte, Francisco C.; Vizcardo-Galindo, G.; Figueroa-Mujica, R.; Day, T.A.; Bird, J.D.; Foster, G.E.; Steinback, C.D.; Brugniaux, J.V.; Champigneulle, B.; Stauffer, E.; Doutreleau, S.; Verges, S.; Swenson, E.R.; Ainslie, P.N. (American Physiological Society, 2022)

High-altitude exposure results in a hyperventilatory-induced respiratory alkalosis followed by renal compensation (bicarbonaturia) to return arterial blood pH (pHa) toward sea-level values. However, acid-base balance has ...
Global Reach 2018: Nitric oxide-mediated cutaneous vasodilation is reduced in chronic, but not acute, hypoxia independently of enzymatic superoxide formation

Coombs, G.B.; Akins, J.D.; Patik, J.C.; Vizcardo-Galindo, G.A.; Figueroa-Mujica, R.; Tymko, M.M.; Stacey, B.S.; Iannetelli, A.; Bailey, D.M.; Villafuerte, Francisco C.; Ainslie, P.N.; Brothers, R.M. (Elsevier, 2021)

We tested the hypotheses that 1) cutaneous microvascular function is impaired by acute normobaric and chronic hypobaric hypoxia and 2) that the superoxide free radical (via NADPH oxidase or xanthine oxidase) contributes ...
Global REACH 2018: renal oxygen delivery is maintained during early acclimatization to 4,330 m

Steele, A.R.; Tymko, M.M.; Meah, V.L.; Simpson, L.L.; Gasho, C.; Dawkins, T.G.; Villafuerte, Francisco C.; Ainslie, P.N.; Stembridge, M.; Moore, J.P.; Steinback, C.D. (American Physiological Society, 2020)

Early acclimatization to high altitude is characterized by various respiratory, hematological, and cardiovascular adaptations that serve to restore oxygen delivery to tissue. However, less is understood about renal function ...
Global REACH 2018: The carotid artery diameter response to the cold pressor test is governed by arterial blood pressure during normoxic but not hypoxic conditions in healthy lowlanders and Andean highlanders

Tymko, M.M.; Hoiland, R.L.; Vermeulen, T.D.; Howe, C.A.; Tymko, C.; Stone, R.M.; Steinback, C.D.; Steele, A.R.; Villafuerte, Francisco C.; Vizcardo-Galindo, G.; Mujica, R.J.F.; Ainslie, P.N. (Wiley, 2020)

New Findings: What is the central question of this study? What is the impact of oxygen on the circulatory responses to an isocapnic cold pressor test (CPT) in lowlanders and Andean highlanders? What is the main finding and ...
Highs and lows of sympathetic neurocardiovascular transduction: influence of altitude acclimatization and adaptation

Berthelsen, L.F.; Fraser, G.M.; Simpson, L.L.; Vanden Berg, E.R.; Busch, S.A.; Steele, A.R.; Meah, V.L.; Lawley, J.S.; Figueroa-Mujíca, R.J.; Vizcardo-Galindo, G.; Villafuerte, Francisco C.; Gasho, C.; Willie, C.K.; Tymko, M.M.; Ainslie, P.N.; Stembridge, M.; Moore, J.P.; Steinback, C.D. (American Physiological Society, 2020)

High-altitude (>2,500 m) exposure results in increased muscle sympathetic nervous activity (MSNA) in acclimatizing lowlanders. However, little is known about how altitude affects MSNA in indigenous high-altitude populations. ...

Listar por autor "Ainslie, P.N."

Listar por autor "Ainslie, P.N."

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