Listar por autor "Bernard, Christine"

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Estimation of pyrazinamidase activity using a cell-free In vitro synthesis of pnca and its association with pyrazinamide susceptibility in Mycobacterium tuberculosis

Rueda, Daniel; Bernard, Christine; Gandy, Lucas; Capton, Estelle; Boudjelloul, Rachid; Brossier, Florence; Veziris, Nicolas; Zimic-Peralta, Mirko Juan; Sougakoff, Wladimir (Medknow Publications, 2018)

Background: The main mechanism of resistance to PZA in Mycobacterium tuberculosis relies on mutations on its pyrazinamidase/nicotinamidase. Recently, a rapid colorimetric test relying on the PCR-based in vitro-synthesized-PZase ...