Listar por autor "Calderón Sánchez, Maritza Mercedes"

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Amplicon sequencing reveals complex infection in infants congenitally infected with Trypanosoma cruzi and informs the dynamics of parasite transmission.

Hakim, Jill M. C.; Waltmann, Andreea; Tinajeros, Freddy; Kharabora, Oksana; Málaga Machaca, Edith Silvia; Calderón Sánchez, Maritza Mercedes; Menduiña, María Del Carmen; Wang, Jeremy; Rueda, Daniel; Zimic-Peralta, Mirko Juan; Verastegui Pimentel, Manuela Renee; Juliano, Jonathan J.; Gilman, Robert H.; Mugnier, Monica R.; Bowman, Natalie M. (Oxford University Press, 2023)

Congenital transmission of Trypanosoma cruzi is an important source of new Chagas infections worldwide. The mechanisms of congenital transmission remain poorly understood, but there is evidence that parasite factors are ...
Antibiotic Use and Resistance Knowledge Assessment of Personnel on Chicken Farms with High Levels of Antimicrobial Resistance: A Cross-Sectional Survey in Ica, Peru

Davalos-Almeyda, Maria; Guerrero, Agustin; Medina, German; Davila-Barclay, Alejandra; Salvatierra, Guillermo; Calderón Sánchez, Maritza Mercedes; Gilman, Robert Hugh; Tsukayama Cisneros, Pablo (MDPI, 2022)

Poultry farming represents Peru’s primary food animal production industry, where antimicrobial growth promoters are still commonly used, exerting selective pressure on intestinal microbial populations. Consumption and ...
Anti–MSP-10 IgG indicates recent exposure to Plasmodium vivax infection in the Peruvian Amazon

Rosas-Aguirre, A.; Patra, K.P.; Calderón Sánchez, Maritza Mercedes; Torres Fajardo, Katherine Jessica; Gamboa Vilela, Dionicia Baziliza; Arocutipa, E.; Málaga, E.; Garro, K.; Fernández, C.; Trompeter, G.; Alnasser, Y.; Llanos Cuentas, Elmer Alejandro; Gilman, Robert Hugh; Vinetz, Joseph Michael (American Society for Clinical Investigation, 2020)

BACKGROUND. Serological tools for the accurate detection of recent malaria exposure are needed to guide and monitor malaria control efforts. IgG responses against Plasmodium vivax and P. falciparum merozoite surface ...
Assessment of an automated capillary system for Plasmodium vivax microsatellite genotyping

Manrique Valverde, Paulo Cesar; Hoshi, Mari; Fasabi, Manuel; Nolasco, Oscar; Yori, Pablo; Calderón Sánchez, Maritza Mercedes; Gilman, Robert Hugh; Kosek, Margaret N.; Vinetz, Joseph Michael; Gamboa Vilela, Dionicia Baziliza (BioMed Central, 2015)

BACKGROUND: Several platforms have been used to generate the primary data for microsatellite analysis of malaria parasite genotypes. Each has relative advantages but share a limitation of being time- and cost-intensive. A ...
Building Public Health Capacity through a Sustainable South-South-North Training Program

Clark, T.; Verastegui Pimentel, Manuela Renee; Tinajeros, F.; Calderón Sánchez, Maritza Mercedes; Colanzi, R.; Gilman, Robert Hugh (American Society of Tropical Medicine and Hygiene, 2020)

Capacity building in public health is an urgent global priority. Recently, there has been an increasing emphasis on South-South and triangular cooperation. We describe our experience with a public health training collaboration ...
C57BL/6 α-1,3-Galactosyltransferase knockout mouse as an animal model for experimental Chagas disease

Valencia Ayala, Edward; Rodrigues da Cunha, Gisele; Araujo Azevedo, Maira; Calderón Sánchez, Maritza Mercedes; Jimenez, Juan; Venuto, Ana Paula; Gazzinelli, Ricardo; Ynocente Lavalle, Raúl Jesus; Vidal Riva, Angela Giovana; Hincapie, Robert; Finn, M. G.; Marques, Alexandre F. (American Chemical Society, 2020)

The leading animal model of experimental Chagas disease, the mouse, plays a significant role in studies for vaccine development, diagnosis, and human therapies. Humans, along with Old World primates, alone among mammals, ...
Clinical and Metagenomic Characterization of Neurological Infections of People With Human Immunodeficiency Virus in the Peruvian Amazon.

Steinberg, Hannah E.; Ramachandran, Prashanth S.; Diestra Calderon, Andrea Jackeline; Pinchi, Lynn; Ferradas Carrillo, Cusi; Kirwan, Daniela E.; Diaz, Monica M.; Sciaudone, Michael; Wapniarski, Annie; Zorn, Kelsey C.; Calderón Sánchez, Maritza Mercedes; Cabrera, Lilia; Pinedo-Cancino, Viviana; Wilson, Michael R.; Asayag, Cesar Ramal; Gilman, Robert H.; Bowman, Natalie M. (Oxford University Press, 2023)

BACKGROUND: Neurological opportunistic infections cause significant morbidity and mortality in people with human immunodeficiency virus (HIV) but are difficult to diagnose. METHODS: One hundred forty people with HIV with ...
Colorimetric Detection of Plasmodium vivax in Urine Using MSP10 Oligonucleotides and Gold Nanoparticles

Alnasser, Yossef; Ferradas, Cusi; Clark, Taryn; Calderón Sánchez, Maritza Mercedes; Gurbillon, Alejandro; Gamboa Vilela, Dionicia Baziliza; McKakpo, Uri S.; Quakyi, Isabella A.; Bosompem, Kwabena M.; Sullivan, David J.; Vinetz, Joseph Michael; Gilman, Robert Hugh (Public Library of Science, 2016)

Plasmodium vivax is the most prevalent cause of human malaria in the world and can lead to severe disease with high potential for relapse. Its genetic and geographic diversities make it challenging to control. P. vivax is ...
Deep sequencing to detect diversity of Trypanosoma cruzi infection in patients co-infected with HIV and Chagas disease

Bowman, Natalie M.; Balasubramanian, Sujata; Gilman, Robert Hugh; Parobek, Christian; Calderón Sánchez, Maritza Mercedes; Waltmann, Andreea; Messenger, Louisa A.; Sanchez, Leny; Bern, Caryn; Juliano, Jonathan J. (Oxford University Press, 2021)

Chagas disease, caused by Trypanosoma cruzi, can reactivate and cause severe acute disease in immunocompromised patients such as those infected with HIV. We conducted amplicon deep sequencing of a 327-base pair fragment ...
Detection of toxoplasmic encephalitis in HIV positive patients in urine with hydrogel nanoparticles

Steinberg, Hannah E.; Bowman, Natalie M.; Diestra, Andrea; Ferradas, Cusi; Russo, Paul; Clark, Daniel E.; Zhu, Deanna; Magni, Ruben; Málaga, Edith; Díaz, Mónica; Pinedo-Cancino, Viviana; Ramal Asayag, Cesar; Calderón Sánchez, Maritza Mercedes; Carruthers, Vern B.; Liotta, Lance A.; Gilman, Robert Hugh; Luchini, Alessandra (Public Library of Science, 2021)

BACKGROUND: Diagnosis of toxoplasmic encephalitis (TE) is challenging under the best clinical circumstances. The poor clinical sensitivity of quantitative polymerase chain reaction (qPCR) for Toxoplasma in blood and CSF ...
Development of a novel protocol based on blood clot to improve the sensitivity of qPCR detection of toxoplasma gondii in peripheral blood specimens

Gutierrez Loli, Renzo Marcelo; Ferradas, C.; Diestra, A.; Traianou, A.; Bowman, N.; Bok, J.; Reimer-McAtee, M.; Ramal, C.; Ticona, E.; Steinberg, H.; Mayta, H.; Calderón Sánchez, Maritza Mercedes; Calla Choque, Jaeson Santos; Sterling, C.; Gilman, Robert Hugh; Pinedo, L.C.; Valencia, G.; Sanchez, L.; Málaga, E.; Zhu, D.; Jiménez, J.; Bern, C.; Angulo, N.; Schiaffino Salazar, Francesca; Acosta, J.; Holtz, M.; Clark, D.; Clark, T.; Trompeter, G.; Choi, J.; Gandarilla, O.; Dorn, M.; Fortuny, E.; Galdos, G.; Colanzi, R. (American Society of Tropical Medicine and Hygiene, 2019)

Quantitative polymerase chain reaction (qPCR) for Toxoplasma gondii multicopy genes has emerged as a promising strategy for sensitive detection of parasite DNA. qPCR can be performed from blood samples, which are minimally ...
Etiological Role and Repeated Infections of Sapovirus among Children Aged Less than 2 Years in a Cohort Study in a Peri-urban Community of Peru

Liu, Xiaofang; Jahuira, Helena; Gilman, Robert Hugh; Alva, Alicia; Cabrera, Lilia; Okamoto, Michiko; Xu, Hang; Windle, Henry J.; Kelleher, Dermot; Varela, Marco; Verastegui Pimentel, Manuela Renee; Calderón Sánchez, Maritza Mercedes; Sanchez, Gerardo; Sarabia, Vanessa; Ballard, Sarah B.; Bern, Caryn; Mayta, Holger; Crabtree, Jean E.; Cama, Vitaliano; Saito, Mayuko; Oshitani, Hitoshi (American Society for Microbiology, 2016)

Human sapovirus has been shown to be one of the most important etiologies in pediatric patients with acute diarrhea. However, very limited data are available about the causative roles and epidemiology of sapovirus in ...
A foodborne outbreak of brucellosis at a police station cafeteria, Lima, Peru

Román, Karina; Castillo, Rosa; Gilman, Robert Hugh; Calderón Sánchez, Maritza Mercedes; Vivar, Aldo; Céspedes, Manuel; Smits, Henk L.; Meléndez, Paolo; Gotuzzo Herencia, José Eduardo; Guerra, Humberto; Maves, Ryan C.; Matthias, Michael A.; Vinetz, Joseph Michael; Saito, Mayuko (American Society of Tropical Medicine and Hygiene, 2013)

Brucella melitensis is highly infectious for humans and can be transmitted to humans in a number of epidemiological contexts. Within the context of an ongoing brucellosis surveillance project, an outbreak at a Peruvian ...
High prevalence of very-low Plasmodium falciparum and Plasmodium vivax parasitaemia carriers in the Peruvian Amazon: insights into local and occupational mobility-related transmission

Carrasco Escobar, Gabriel; Miranda-Alban, Julio; Fernandez-Miñope, Carlos; Brouwer, Kimberly C.; Torres Fajardo, Katherine Jessica; Calderón Sánchez, Maritza Mercedes; Gamboa Vilela, Dionicia Baziliza; Llanos Cuentas, Elmer Alejandro; Vinetz, Joseph Michael (BioMed Central, 2017)

BACKGROUND: The incidence of malaria due both to Plasmodium falciparum and Plasmodium vivax in the Peruvian Amazon has risen in the past 5 years. This study tested the hypothesis that the maintenance and emergence of malaria ...
Household Contamination of Baby Bottles and Opportunities to Improve Bottle Hygiene in Peri-Urban Lima, Peru

Rothstein, Jessica D.; Mendoza, Alejandra Llican; Cabrera, Lilia Z.; Pachas, Jessica; Calderón Sánchez, Maritza Mercedes; Pajuelo Travezaño, Monica Jhenny; Caulfield, Laura E.; Winch, Peter J.; Gilman, Robert Hugh (American Society of Tropical Medicine and Hygiene, 2019)

Feeding of infant formula using contaminated bottles may be an important transmission pathway of enteric pathogens during early life. Determinants of suboptimal bottle hygiene and the feasibility and acceptability of ...
Interconnected microbiomes and resistomes in low-income human habitats

Pehrsson, Erica C.; Tsukayama Cisneros, Pablo; Patel, Sanket; Mejia-Bautista, Melissa; Sosa-Soto, Giordano; Navarrete, Karla M.; Calderón Sánchez, Maritza Mercedes; Cabrera, Lilia; Hoyos-Arango, William; Bertoli, M. Teresita; Berg, Douglas E.; Gilman, Robert Hugh; Dantas, Gautam (Springer Nature, 2016)

Antibiotic-resistant infections annually claim hundreds of thousands of lives worldwide. This problem is exacerbated by exchange of resistance genes between pathogens and benign microbes from diverse habitats. Mapping ...
Market Chickens as a Source of Antibiotic-Resistant Escherichia coli in a Peri-Urban Community in Lima, Peru

Murray, Matthew; Salvatierra, Guillermo; Dávila-Barclay, Alejandra; Ayzanoa, Brenda; Castillo-Vilcahuaman, Camila; Huang, Michelle; Pajuelo Travezaño, Monica Jhenny; Lescano Guevara, Andres Guillermo; Cabrera, Lilia; Calderón Sánchez, Maritza Mercedes; Berg, Douglas E.; Gilman, Robert Hugh; Tsukayama Cisneros, Pablo (Frontiers Media, 2021)

The widespread and poorly regulated use of antibiotics in animal production in low- and middle-income countries (LMICs) is increasingly associated with the emergence and dissemination of antibiotic resistance genes (ARGs) ...
Microgeographical differences of Plasmodium vivax relapse and re-infection in the Peruvian Amazon

Chuquiyauri, Raul; Peñataro, Pablo; Brouwer, Kimberly C.; Fasabi, Manuel; Calderón Sánchez, Maritza Mercedes; Torres, Sonia; Gilman, Robert Hugh; Kosek, Margaret; Vinetz, Joseph Michael (American Society of Tropical Medicine and Hygiene, 2013)

To determine the magnitude of Plasmodium vivax relapsing malaria in rural Amazonia, we carried out a study in four sites in northeastern Peru. Polymerase chain reaction-restriction fragment length polymorphism of PvMSP-3α ...
Perfiles hematológicos en pacientes infectados con malaria en un área endémica del Perú

Pinedo-Cancino, Viviana; Arista, Katty M.; Valle-Campos, Andree; Saavedra-Langer, Rafael; Roca, Cristian; Ramos-Rincon, Jose-Manuel; Calderón Sánchez, Maritza Mercedes; Branch, Oralee H. (Instituto Nacional de Salud, 2022)

Objectives. To evaluate the variation of hematological profiles of patients infected with uncomplicated Plasmodium vivax (Pv) and P. falciparum (Pf) malaria before, during and after treatment in a population of the Loreto ...
Polyclonal antibodies for the detection of Trypanosoma cruzi circulating antigens

Málaga-Machaca, Edith S.; Romero-Ramirez, Alessandra; Gilman, Robert Hugh; Astupiña-Figueroa, Sofía; Angulo, Noelia; Florentini, Alejandro; Lovon-Luque, Cinthya J.; Gonza, Remo A.; Del Carpio-Sanz, Ada; Cabello, Inés; Camargo, Rosina; Recuenco, Fernando; Barrueta-Soria, Liliam A.; Verastegui Pimentel, Manuela Renee; Calderón Sánchez, Maritza Mercedes; Mayta, Holger (Public Library of Science, 2017)

BACKGROUND: Detection of Trypanosoma cruzi antigens in clinical samples is considered an important diagnostic tool for Chagas disease. The production and use of polyclonal antibodies may contribute to an increase in the ...