Listar por autor "Coronel, Jorge"

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  • Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South Africa 
    Grint, Daniel; Alisjhabana, Bachti; Ugarte Gil, Cesar Augusto; Riza, Anca-Leila; Walzl, Gerhard; Pearson, Fiona; Ruslami, Rovina; Moore, David Alexander James; Ioana, Mihai; McAllister, Susan; Ronacher, Katharina; Koeseomadinata, Raspati C.; Kerry-Barnard, Sarah R.; Coronel, Jorge; Malherbe, Stephanus T.; Dockrell, Hazel M.; Hill, Philip C.; Van Crevel, Reinout; Critchley, Julia A. (World Health Organization, 2018)
    Objective: To evaluate the performance of diagnostic tools for diabetes mellitus, including laboratory methods and clinical risk scores, in newly-diagnosed pulmonary tuberculosis patients from four middle-income countries. ...
  • The Association between Mycobacterium Tuberculosis Genotype and Drug Resistance in Peru 
    Grandjean, Louis; Iwamoto, Tomotada; Lithgow, Anna; Gilman, Robert Hugh; Arikawa, Kentaro; Nakanishi, Noriko; Martin, Laura; Castillo, Edith; Alarcon, Valentina; Coronel, Jorge; Solano, Walter; Aminian, Minoo; Guezala, Claudia; Rastogi, Nalin; Couvin, David; Sheen Cortavarria, Patricia; Zimic-Peralta, Mirko Juan; Moore, David Alexander James (Public Library of Science, 2015)
    BACKGROUND: The comparison of Mycobacterium tuberculosis bacterial genotypes with phenotypic, demographic, geospatial and clinical data improves our understanding of how strain lineage influences the development of ...
  • A case report of transmission and disease caused by Mycobacterium caprae and Mycobacterium bovis in Lima, Peru. 
    Shrestha, Amber; Picoy, Janeth; Torres, Arturo; Moore, David Alexander James; Gilman, Robert Hugh; Coronel, Jorge; Grandjean, Louis (BioMed Central, 2021)
    BACKGROUND: The Tuberculosis (TB) burden in Peru is significant with respect to both disease morbidity and mortality. Furthermore the recent diversification of farming enterprise to include a wide range of animal species ...
  • Convergent evolution and topologically disruptive polymorphisms among multidrug-resistant tuberculosis in Peru 
    Grandjean, Louis; Gilman, Robert Hugh; Iwamoto, Tomatada; Köser, Claudio U.; Coronel, Jorge; Zimic-Peralta, Mirko Juan; Török, M. Estee; Ayabina, Diepreye; Kendall, Michelle; Fraser, Christophe; Harris, Simon; Parkhill, Julian; Peacock, Sharon J.; Moore, David Alexander James; Colijn, Caroline (Public Library of Science, 2017)
    BACKGROUND: Multidrug-resistant tuberculosis poses a major threat to the success of tuberculosis control programs worldwide. Understanding how drug-resistant tuberculosis evolves can inform the development of new therapeutic ...
  • Cough dynamics in adults receiving tuberculosis treatment 
    Lee, Gwenyth O.; Comina, Germán; Hernandez-Cordova, Gustavo; Naik, Nehal; Gayoso, Oscar; Ticona, Eduardo; Coronel, Jorge; Evans, Carlton Anthony William; Zimic-Peralta, Mirko Juan; Paz-Soldan Parlette, Valerie Andrea; Gilman, Robert Hugh; Oberhelman, Richard (Public Library of Science, 2020)
    Cough is a characteristic symptom of tuberculosis, is the main cause of transmission, and is used to assess treatment response. We aimed to identify the best measure of cough severity and characterize changes during initial ...
  • A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates 
    Fowler, P.W.; Wright, C.; Spiers, H.; Zhu, T.; Baeten, E.M.L.; Hoosdally, S.W.; Cruz, A.L.G.; Roohi, A.; Kouchaki, S.; Walker, T.M.; Peto, T.E.A.; Miller, G.; Lintott, C.; Clifton, D.; Crook, D.W.; Walker, A.S.; Barilar, I.; Battaglia, S.; Borroni, E.; Brandao, A.P.; Brankin, A.; Cabibbe, A.M.; Carter, J.; Chetty, D.; Cirillo, D.M.; Claxton, P.; Clifton, D.A.; Cohen, T.; Coronel, Jorge; Dreyer, V.; Earle, S.G.; Escuyer, V.; Ferrazoli, L.; Gao, G.F.; Gardy, J.; Gharbia, S.; Ghisi, K.T.; Ghodousi, A.; Grandjean, Louis; Grazian, C.; Groenheit, R.; Guthrie, J.L.; He, W.; Hoffmann, H.; Hoosdally, S.J.; Martinhunt, M.; Iqbal, Z.; Ismail, N.A.; Jarrett, L.; Joseph, L.; Jou, R.; Kambli, P.; Khot, R.; Knaggs, J.; Koch, A.; Kohlerschmidt, D.; Lachapelle, A.S.; Lalvani, A.; Lapierre, S.G.; Laurenson, I.F.; Letcher, B.; Lin, W.-H.; Liu, C.; Liu, D.; Malone, K.M.; Mandal, A.; Mansjõ, M.; Matias, D.; Meintjes, G.; Mendes, F.D.F.; Merker, M.; Mihalic, M.; Millard, J.; Miotto, P.; Mistry, N.; Moore, David Alexander James; Musser, K.A.; Ngcamu, D.; Nhung, H.N.; Niemann, S.; Nilgiriwala, K.S.; Nimmo, C.; O’Donnell, M.; Okozi, N.; Oliveira, R.S.; Omar, S.V.; Paton, N.; Pinhata, J.M.W.; Plesnik, S.; Puyen, Z.M.; Rabodoarivelo, M.S.; Rakotosamimanana, N.; Rancoita, P.M.V.; Rathod, P.; Robinson, E.; Rodger, G.; Rodrigues, C.; Rodwell, T.C.; Santos-Lazaro, D.; Shah, S.; Kohl, T.A.; Smith, G.; Solano, Walter; Spitaleri, A.; Supply, P.; Steyn, A.J.C.; Surve, U.; Tahseen, S.; Thuong, N.T.T.; Thwaites, G.; Todt, K.; Trovato, A.; Utpatel, C.; Van Rie, A.; Vijay, S.; Walker, A.S.; Warren, R.; Werngren, J.; Wijkander, M.; Wilkinson, R.J.; Wilson, D.J.; Wintringer, P.; Xiao, Y.-X.; Yang, Y.; Yanlin, Z.; Yao, S.-Y.; Zhu, B.; The Zooniverse Volunteer Community; The CRyPTIC Consortium (eLife Sciences Publications, 2022)
    Tuberculosis is a respiratory disease that is treatable with antibiotics. An increasing prevalence of resistance means that to ensure a good treatment outcome it is desirable to test the susceptibility of each infection ...
  • Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection 
    Dudley, Matthew Z.; Sheen Cortavarria, Patricia; Gilman, Robert Hugh; Ticona, Eduardo; Friedland, Jon S.; Kirwan, Daniela E.; Caviedes, Luz; Rodriguez, Richard; Cabrera, Lilia Z.; Coronel, Jorge; Grandjean, Louis; Moore, David Alexander James; Evans, Carlton Anthony William; Huaroto, Luz; Chavez-Perez, Victor; Zimic-Peralta, Mirko Juan (American Society of Tropical Medicine and Hygiene, 2016)
    Hospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)–positive patients, as these patients are at heightened risk of developing ...
  • dfrA thyA Double Deletion in para-Aminosalicylic Acid-Resistant Mycobacterium tuberculosis Beijing Strains 
    Moradigaravand, Danesh; Grandjean, Louis; Martinez, Elena; Li, Hao; Zheng, Jun; Coronel, Jorge; Moore, David Alexander James; Torok, M. Estee; Sintchenko, Vitali; Huang, Hairong; Javid, Babak; Parkhill, Julian; Peacock, Sharon-J.; Koser, Claudio-U. (American Society for Microbiology, 2016)
    Para-Aminosalicylic acid (PAS) is a group 4 antituberculosis agent. It targets folate metabolism as shown in Fig. S1 in the supplemental material, which also summarizes the known mechanisms of resistance to this prodrug. ...
  • Dynamics of Cough Frequency in Adults Undergoing Treatment for Pulmonary Tuberculosis 
    Proano, Alvaro; Bravard, Marjory A.; Lopez, Jose W.; Lee, Gwenyth O.; Bui, David; Datta, Sumona; Comina, German; Zimic-Peralta, Mirko Juan; Coronel, Jorge; Caviedes, Luz; Cabrera, Jose L.; Salas, Antonio; Ticona, Eduardo; Vu, Nancy M.; Kirwan, Daniela E.; Loader, Maria-Cristina I.; Friedland, Jon S.; Moore, David Alexander James; Evans, Carlton Anthony William; Tracey, Brian H.; Gilman, Robert Hugh (Oxford University Press, 2017)
    Background: Cough is the major determinant of tuberculosis transmission. Despite this, there is a paucity of information regarding characteristics of cough frequency throughout the day and in response to tuberculosis ...
  • Epidemiological cutoff values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing of M. tuberculosis 
    Fowler, P.W.; Barilar, I.; Battaglia, S.; Borroni, E.; Brandao, A.P.; Brankin, A.; Cabibbe, A.M.; Carter, J.; Cirillo, D.M.; Claxton, P.; Clifton, D.A.; Cohen, T.; Coronel, Jorge; Crook, D.W.; Dreyer, V.; Earle, S.G.; Escuyer, V.; Ferrazoli, L.; Gao, G.F.; Gardy, J.; Gharbia, S.; Ghisi, K.T.; Ghodousi, A.; Cruz, A.L.G.; Grandjean, Louis; Grazian, C.; Groenheit, R.; Guthrie, J.L.; He, W.; Hoffmann, H.; Hoosdally, S.J.; Hunt, M.; Iqbal, Z.; Ismail, N.A.; Jarrett, L.; Joseph, L.; Jou, R.; Kambli, P.; Khot, R.; Knaggs, J.; Koch, A.; Kohlerschmidt, D.; Kouchaki, S.; Lachapelle, A.S.; Lalvani, A.; Lapierre, S.G.; Laurenson, I.F.; Letcher, B.; Lin, W.-H.; Liu, C.; Liu, D.; Malone, K.M.; Mandal, A.; Mansjö, M.; Matias, D.; Meintjes, G.; de Freitas Mendes, F.; Merker, M.; Mihalic, M.; Millard, J.; Miotto, P.; Mistry, N.; Moore, David Alexander James; Musser, K.A.; Ngcamu, D.; Nhung, H.N.; Niemann, S.; Nilgiriwala, K.S.; Nimmo, C.; Okozi, N.; Oliveira, R.S.; Omar, S.V.; Paton, N.; Peto, T.E.A.; Pinhata, J.M.W.; Plesnik, S.; Puyen, Z.M.; Rabodoarivelo, M.S.; Rakotosamimanana, N.; Rancoita, P.M.V.; Rathod, P.; Robinson, E.; Rodger, G.; Rodrigues, C.; Rodwell, T.C.; Roohi, A.; Santos-Lazaro, D.; Shah, S.; Kohl, T.A.; Smith, G.; Solano, Walter; Spitaleri, A.; Supply, P.; Surve, U.; Tahseen, S.; Thuong, N.T.T.; Thwaites, G.; Todt, K.; Trovato, A.; Utpatel, C.; Van Rie, A.; Vijay, S.; Walker, T.M.; Walker, A.S.; Warren, R.; Werngren, J.; Wijkander, M.; Wilkinson, R.J.; Wilson, D.J.; Wintringer, P.; Xiao, Y.-X.; Yang, Y.; Yanlin, Z.; Yao, S.-Y.; Zhu, B. (European Respiratory Society, 2022)
    Drug susceptibility testing of M. tuberculosis is rooted in a binary susceptible/resistant paradigm. Whilst there are considerable advantages in measuring the minimum inhibitory concentrations (MICs) of a panel of drugs ...
  • Evaluation of a lens-free imager to facilitate tuberculosis diagnostics in MODS 
    Solis, Leonardo; Coronel, Jorge; Rueda, Daniel; Gilman, Robert Hugh; Sheen Cortavarria, Patricia; Zimic-Peralta, Mirko Juan (Elsevier, 2015)
    Tuberculosis (TB) control efforts are hampered by a mismatch in diagnostic technology. Lack of adequate early diagnostics and Multi-drug resistant (MDR) detection is a critical problem in control efforts. Alternate and ...
  • Evaluation of the broth microdilution plate methodology for susceptibility testing of Mycobacterium tuberculosis in Peru 
    Puyen, Zully M.; Santos-Lazaro, David; Vigo, Aiko N.; Coronel, Jorge; Alarcon, Miriam J.; Cotrina, Vidia V.; Moore, David Alexander James (BioMed Central, 2022)
    Background: Tuberculosis (TB) is a communicable, preventable and curable disease caused by the bacterium Mycobacterium tuberculosis (MTB). Peru is amongst the 30 countries with the highest burden of multidrug-resistant ...
  • A field evaluation of the Hardy TB MODS kit™ for the rapid phenotypic diagnosis of tuberculosis and multi-drug resistant tuberculosis 
    Martin, Laura; Coronel, Jorge; Faulx, Dunia; Valdez, Melissa; Metzler, Mutsumi; Crudder, Chris; Castillo, Edith; Caviedes, Luz; Grandjean, Louis; Rodriguez, Mitzi; Friedland, Jon S.; Gilman, Robert Hugh; Moore, David Alexander James (Public Library of Science, 2014)
    BACKGROUND: Even though the WHO-endorsed, non-commercial MODS assay offers rapid, reliable TB liquid culture and phenotypic drug susceptibility testing (DST) at lower cost than any other diagnostic, uptake has been patchy. ...
  • Genomic signatures of pre-resistance in Mycobacterium tuberculosis. 
    Torres Ortiz, Arturo; Coronel, Jorge; Vidal, Julia Rios; Bonilla, Cesar; Moore, David Alexander James; Gilman, Robert Hugh; Balloux, Francois; Kon, Onn Min; Didelot, Xavier; Grandjean, Louis (Springer Nature, 2021)
    Recent advances in bacterial whole-genome sequencing have resulted in a comprehensive catalog of antibiotic resistance genomic signatures in Mycobacterium tuberculosis. With a view to pre-empt the emergence of resistance, ...
  • Impact of intermediate hyperglycaemia as well as diabetes on immune dysfunction in tuberculosis. 
    Eckold, Clare; Kumar, Vinod; Weiner Rd, January; Alisjahbana, Bachti; Riza, Anca-Lelia; Ronacher, Katharina; Coronel, Jorge; Kerry-Barnard, Sarah; Malherbe, Stephanus T.; Kleynhans, Leanie; Stanley, Kim; Ruslami, Rovina; Ioana, Mihai; Ugarte Gil, Cesar Augusto; Walzl, Gerhard; van Crevel, Reinout; Wijmenga, Cisca; Critchley, Julia A.; Dockrell, Hazel M.; Cliff, Jacqueline M. (Oxford University Press, 2020)
    BACKGROUND: People living with diabetes have an increased risk of developing active tuberculosis and are more likely to have poor tuberculosis-treatment outcomes, which may impact on control of tuberculosis as the prevalence ...
  • Induced Sputum MMP-1, -3 & -8 Concentrations during Treatment of Tuberculosis 
    Ugarte Gil, Cesar Augusto; Elkington, Paul; Gilman, Robert Hugh; Coronel, Jorge; Tezera, Liku B.; Bernabé Ortiz, Antonio; Gotuzzo Herencia, José Eduardo; Friedland, Jon S.; Moore, David Alexander James (Public Library of Science, 2013)
    Introduction: Tuberculosis (TB) destroys lung tissues and this immunopathology is mediated in part by Matrix Metalloproteinases (MMPs). There are no data on the relationship between local tissue MMPs concentrations, ...
  • Investigating spillover of multidrug-resistant tuberculosis from a prison: a spatial and molecular epidemiological analysis 
    Warren, Joshua L.; Grandjean, Louis; Moore, David Alexander James; Lithgow, Anna; Coronel, Jorge; Sheen Cortavarria, Patricia; Zelner, Jonathan L.; Andrews, Jason R.; Cohen, Ted (BioMed Central, 2018)
    BACKGROUND: Congregate settings may serve as institutional amplifiers of tuberculosis (TB) and multidrug-resistant tuberculosis (MDR-TB). We analyze spatial, epidemiological, and pathogen genetic data prospectively collected ...
  • Low-cost 3D-printed inverted microscope to detect Mycobacterium tuberculosis in a MODS culture 
    Salguedo, Mario; Zarate, Guillermo; Coronel, Jorge; Comina, Germán; Gilman, Robert Hugh; Sheen Cortavarria, Patricia; Oberhelman, Richard; Zimic-Peralta, Mirko Juan (Elsevier, 2022)
    MODS, an assay for diagnosis of tuberculosis and drug-susceptibility, is based in the microscopic observation of the characteristic cords of Mycobacterium tuberculosis colonies grown in liquid media. An inverted optical ...
  • Minimum inhibitory concentration distributions for first- and second-line antimicrobials against Mycobacterium tuberculosis 
    Burke, Rachael M.; Coronel, Jorge; Moore, David Alexander James (Microbiology Society, 2017)
    We report the range of minimum inhibitory concentrations for six antimicrobial drugs in 228 clinical Mycobacterium tuberculosis (MTB) isolates from three distinct groups of patients (unselected patients, patients at high ...
  • Morphological characterization of Mycobacterium tuberculosis in a MODS culture for an automatic diagnostics through pattern recognition 
    Alva, Alicia; Aquino, Fredy; Gilman, Robert Hugh; Olivares, Carlos; Requena, David; Gutiérrez, Andrés H.; Caviedes, Luz; Coronel, Jorge; Larson, Sandra; Sheen Cortavarria, Patricia; Moore, David Alexander James; Zimic-Peralta, Mirko Juan (Public Library of Science, 2013)
    Tuberculosis control efforts are hampered by a mismatch in diagnostic technology: modern optimal diagnostic tests are least available in poor areas where they are needed most. Lack of adequate early diagnostics and MDR ...

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