Listar por autor "Dheda, Keertan"

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  • Design and use of mouse control DNA for DNA biomarker extraction and PCR detection from urine: Application for transrenal Mycobacterium tuberculosis DNA detection 
    Bordelon, Hali; Ricks, Keersten M.; Pask, Megan E.; Russ, Patricia K.; Solinas, Francesca; Baglia, Mark L.; Short, Philip A.; Nel, Andrew; Blackburn, Jonathan; Dheda, Keertan; Zamudio Fuertes, Carlos Eduardo; Cáceres Nakiche, Tatiana; Wright, David W.; Haselton, Frederick R.; Pettit, April C. (Elsevier, 2017)
    Urine samples are increasingly used for diagnosing infections including Escherichia coli, Ebola virus, and Zika virus. However, extraction and concentration of nucleic acid biomarkers from urine is necessary for many ...
  • Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis 
    Coll, Francesc; Phelan, Jody; Hill-Cawthorne, Grant A.; Nair, Mridul B.; Mallard, Kim; Ali, Shahjahan; Abdallah, Abdallah M.; Alghamdi, Saad; Alsomali, Mona; Ahmed, Abdallah O.; Portelli, Stephanie; Oppong, Yaa; Alves, Adriana; Bessa, Theolis Barbosa; Campino, Susana; Caws, Maxine; Chatterjee, Anirvan; Crampin, Amelia C.; Dheda, Keertan; Furnham, Nicholas; Glynn, Judith R.; Grandjean, Louis; Minh Ha, Dang; Hasan, Rumina; Hasan, Zahra; Hibberd, Martin L.; Joloba, Moses; Jones-López, Edward C.; Matsumoto, Tomoshige; Miranda, Anabela; Moore, David Alexander James; Mocillo, Nora; Panaiotov, Stefan; Parkhill, Julian; Penha, Carlos; Perdigão, João; Portugal, Isabel; Rchiad, Zineb; Robledo, Jaime; Sheen Cortavarria, Patricia; Shesha, Nashwa Talaat; Sirgel, Frik A.; Sola, Christophe; Oliveira Sousa, Erivelton; Streicher, Elizabeth M.; Helden, Paul Van; Viveiros, Miguel; Warren, Robert M.; McNerney, Ruth; Pain, Arnab; Clark, Taane G. (Springer Nature, 2018)
    To characterize the genetic determinants of resistance to antituberculosis drugs, we performed a genome-wide association study (GWAS) of 6,465 Mycobacterium tuberculosis clinical isolates from more than 30 countries. A ...
  • Performance of the TB-LAMP diagnostic assay in reference laboratories: Results from a multicentre study 
    Pham, Thu Hang; Peter, Jonathan; Mello, Fernanda C. Q.; Parraga, Tommy; Lan, Nguyen Thi Ngoc; Nabeta, Pamela; Valli, Eloise; Cáceres Nakiche, Tatiana; Dheda, Keertan; Dorman, Susan E.; Hillemann, Doris; Gray, Christen M.; Perkins, Mark D. (Elsevier, 2018)
    OBJECTIVE: To evaluate the diagnostic performance of TB-LAMP, a manual molecular tuberculosis (TB) detection method, and provide comparison to the Xpert MTB/RIF assay. METHODS: In a large multicentre study, two sputum ...
  • Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages 
    Phelan, Jody-E.; Coll, Francesc; Bergval, Indra; Anthony, Richard-M.; Warren, Rob; Sampson, Samantha-L.; Gey-van-Pittius, Nicolaas-C.; Glynn, Judith-R.; Crampin, Amelia-C.; Alves, Adriana; Bessa, Theolis-Barbosa; Campino, Susana; Dheda, Keertan; Grandjean, Louis; Hasan, Rumina; Hasan, Zahra; Miranda, Anabela; Moore, David Alexander James; Panaiotov, Stefan; Perdigao, Joao; Portugal, Isabel; Sheen Cortavarria, Patricia; de-Oliveira-Sousa, Erivelton; Streicher, Elizabeth-M.; van-Helden, Paul-D.; Viveiros, Miguel; Hibberd, Martin-L.; Pain, Arnab; McNerney, Ruth; Clark, Taane-G. (BioMed Central, 2016)
    BACKGROUND: Approximately 10% of the Mycobacterium tuberculosis genome is made up of two families of genes that are poorly characterized due to their high GC content and highly repetitive nature. The PE and PPE families ...

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